| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.140684 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.123377 |
| MT2A | metallothionein 2A | 0.121433 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.110256 |
| LDHA | lactate dehydrogenase A | 0.10522 |
| B2M | beta-2-microglobulin | 0.0936981 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0878567 |
| CD44 | CD44 molecule (Indian blood group) | 0.0866487 |
| ANXA2 | annexin A2 | 0.075218 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0711513 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0666749 |
| CSTB | cystatin B (stefin B) | 0.0662209 |
| CAVIN1 | caveolae associated protein 1 | 0.0655678 |
| LOX | lysyl oxidase | 0.065017 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0647295 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0631874 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0604058 |
| ENO1 | enolase 1, (alpha) | 0.0584136 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0559911 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0554491 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0522307 |
| DST | dystonin | 0.0494929 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0494152 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0491572 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0479336 |
| MKI67 | marker of proliferation Ki-67 | 0.0469638 |
| HMGB2 | high mobility group box 2 | 0.04647 |
| KLF6 | Kruppel-like factor 6 | 0.0456348 |
| STC1 | stanniocalcin 1 | 0.0444907 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0439602 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0416053 |
| SQSTM1 | sequestosome 1 | 0.0412717 |
| RTN4 | reticulon 4 | 0.0395992 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0394848 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0383405 |
| THBS2 | thrombospondin 2 | 0.0372896 |
| COL3A1 | collagen, type III, alpha 1 | 0.0367898 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0364922 |
| SEPTIN7 | septin 7 | 0.0358085 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0348855 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0337462 |
| TPR | translocated promoter region, nuclear basket protein | 0.0335243 |
| TPM3 | tropomyosin 3 | 0.0334524 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0331921 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0328277 |
| GOLGA4 | golgin A4 | 0.03243 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0324232 |
| HDAC9 | histone deacetylase 9 | 0.0324111 |
| APP | amyloid beta (A4) precursor protein | 0.0323043 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0320263 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0319285 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0316762 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0315046 |
| PRRC2C | proline-rich coiled-coil 2C | 0.031263 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0307729 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0306123 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0301283 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0300661 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0296306 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0295763 |
| CEP350 | centrosomal protein 350kDa | 0.0295694 |
| OGA | O-GlcNAcase | 0.0295546 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0292433 |
| RPS3 | ribosomal protein S3 | 0.0289636 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0287917 |
| ANLN | anillin, actin binding protein | 0.028341 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0280298 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0279089 |
| DIAPH3 | diaphanous-related formin 3 | 0.0274271 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0270945 |
| SON | SON DNA binding protein | 0.0270043 |
| GLIS3 | GLIS family zinc finger 3 | 0.0267852 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0267118 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0267051 |
| PKM | pyruvate kinase, muscle | 0.0266034 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0263796 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0262728 |
| CENPF | centromere protein F, 350/400kDa | 0.0261733 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0257812 |
| PRSS23 | protease, serine, 23 | 0.0256158 |
| RAI14 | retinoic acid induced 14 | 0.0253923 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0251316 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0248473 |
| ITGA6 | integrin, alpha 6 | 0.0245701 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0245048 |
| SET | SET nuclear proto-oncogene | 0.0243957 |
| MYADM | myeloid-associated differentiation marker | 0.024185 |
| ATP13A3 | ATPase type 13A3 | 0.0240412 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0240133 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0240097 |
| MAP1B | microtubule-associated protein 1B | 0.024006 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0236722 |
| ITSN2 | intersectin 2 | 0.0235688 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0234241 |
| KIF5B | kinesin family member 5B | 0.0233982 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0233745 |
| TXNRD1 | thioredoxin reductase 1 | 0.0229755 |
| RPS12 | ribosomal protein S12 | 0.0228275 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0227042 |
| FLNA | filamin A, alpha | 0.0226651 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.510179 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.176329 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.142796 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.127138 |
| SUCNR1 | succinate receptor 1 | -0.110715 |
| S100A10 | S100 calcium binding protein A10 | -0.10773 |
| TMSB10 | thymosin beta 10 | -0.105326 |
| CDH13 | cadherin 13 | -0.103579 |
| AHNAK | AHNAK nucleoprotein | -0.0983666 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0939152 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0815296 |
| COL5A1 | collagen, type V, alpha 1 | -0.0774607 |
| PLAT | plasminogen activator, tissue | -0.0755161 |
| NAV1 | neuron navigator 1 | -0.0705448 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0685403 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0641956 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0639503 |
| CD99 | CD99 molecule | -0.063911 |
| CUX1 | cut-like homeobox 1 | -0.0578764 |
| FN1 | fibronectin 1 | -0.0576709 |
| MSI2 | musashi RNA-binding protein 2 | -0.0524902 |
| TPM1 | tropomyosin 1 (alpha) | -0.0483299 |
| ACTG1 | actin gamma 1 | -0.0433428 |
| POTEF | POTE ankyrin domain family, member F | -0.0426519 |
| AUTS2 | autism susceptibility candidate 2 | -0.0424252 |
| KRT81 | keratin 81, type II | -0.042365 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0413766 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0411668 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0402514 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0392108 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0376363 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0368361 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0344315 |
| RPL35A | ribosomal protein L35a | -0.0343737 |
| EGFR | epidermal growth factor receptor | -0.0336216 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0329647 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0317751 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0316482 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0300473 |
| CYTH3 | cytohesin 3 | -0.0298693 |
| TNS3 | tensin 3 | -0.0296453 |
| INSIG1 | insulin induced gene 1 | -0.0296358 |
| UBC | ubiquitin C | -0.0283101 |
| EFNA5 | ephrin-A5 | -0.0280545 |
| VEGFC | vascular endothelial growth factor C | -0.0279675 |
| MT1X | metallothionein 1X | -0.0274295 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0260318 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.025764 |
| COL5A2 | collagen, type V, alpha 2 | -0.0240057 |
| ASTN2 | astrotactin 2 | -0.0237216 |
| COL1A1 | collagen, type I, alpha 1 | -0.0233636 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0231685 |
| TAPBP | TAP binding protein (tapasin) | -0.0229237 |
| RPS15 | ribosomal protein S15 | -0.0225635 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0225314 |
| INTS6 | integrator complex subunit 6 | -0.0225264 |
| C12ORF75 | chromosome 12 open reading frame 75 | -0.0223065 |
| CCND1 | cyclin D1 | -0.0221645 |
| NDRG1 | N-myc downstream regulated 1 | -0.0218538 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0216158 |
| RPL34 | ribosomal protein L34 | -0.0215177 |
| DCLK2 | doublecortin-like kinase 2 | -0.0215117 |
| RPS19 | ribosomal protein S19 | -0.0207045 |
| FBXO11 | F-box protein 11 | -0.0205531 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0200691 |
| RPL28 | ribosomal protein L28 | -0.0194802 |
| RPS23 | ribosomal protein S23 | -0.0192764 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0191687 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0185833 |
| RPS11 | ribosomal protein S11 | -0.0184756 |
| VEGFA | vascular endothelial growth factor A | -0.0184281 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0180648 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0179553 |
| IL32 | interleukin 32 | -0.0178517 |
| SASH1 | SAM and SH3 domain containing 1 | -0.017447 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0174033 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.017284 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | -0.0172396 |
| RHOA | ras homolog family member A | -0.0172216 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0171736 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0171479 |
| MX2 | MX dynamin-like GTPase 2 | -0.0168511 |
| JAZF1 | JAZF zinc finger 1 | -0.0167527 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.016707 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0165573 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.016379 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0163189 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0160101 |
| TOX | thymocyte selection-associated high mobility group box | -0.0159371 |
| CD63 | CD63 molecule | -0.0158104 |
| RUNX1 | runt-related transcription factor 1 | -0.0157792 |
| HLA-B | major histocompatibility complex, class I, B | -0.0155669 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0155663 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0153004 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0152773 |
| THY1 | Thy-1 cell surface antigen | -0.0151165 |
| GSE1 | Gse1 coiled-coil protein | -0.0150671 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0149663 |
| S100A6 | S100 calcium binding protein A6 | -0.0149317 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0149026 |
