| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.249063 |
| AREG | amphiregulin | 0.161496 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0808222 |
| NLGN1 | neuroligin 1 | 0.0761119 |
| TUBA1B | tubulin, alpha 1b | 0.061666 |
| RTN4 | reticulon 4 | 0.0466249 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0417492 |
| TPI1 | triosephosphate isomerase 1 | 0.0392907 |
| PFN1 | profilin 1 | 0.0379339 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0372344 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0364985 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0363559 |
| RRM2 | ribonucleotide reductase M2 | 0.0352981 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.034075 |
| PTMS | parathymosin | 0.0326017 |
| CIP2A | cellular inhibitor of PP2A | 0.0324533 |
| RPS12 | ribosomal protein S12 | 0.0306875 |
| SON | SON DNA binding protein | 0.0302257 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0300446 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0275887 |
| WDR43 | WD repeat domain 43 | 0.0262796 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0262402 |
| POTEF | POTE ankyrin domain family, member F | 0.0247878 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0241638 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0240722 |
| EGR1 | early growth response 1 | 0.0238034 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0236737 |
| LDHA | lactate dehydrogenase A | 0.0228776 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0226893 |
| SET | SET nuclear proto-oncogene | 0.0226404 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0222829 |
| CENPE | centromere protein E, 312kDa | 0.0221441 |
| RPS3 | ribosomal protein S3 | 0.0213871 |
| MYADM | myeloid-associated differentiation marker | 0.0213238 |
| KIF18A | kinesin family member 18A | 0.0212777 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0204997 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0204518 |
| YBX3 | Y box binding protein 3 | 0.0201424 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0198329 |
| NDC80 | NDC80 kinetochore complex component | 0.0195731 |
| TMEM41B | transmembrane protein 41B | 0.0194809 |
| CCNL1 | cyclin L1 | 0.019468 |
| ENO1 | enolase 1, (alpha) | 0.0194554 |
| EDN1 | endothelin 1 | 0.0192266 |
| DIAPH3 | diaphanous-related formin 3 | 0.0188806 |
| CBX3 | chromobox homolog 3 | 0.0187843 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0184402 |
| PCBP2 | poly(rC) binding protein 2 | 0.0184334 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0181827 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.018114 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0180813 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0179964 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.017842 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0177591 |
| KIF4A | kinesin family member 4A | 0.0176757 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0175736 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0174129 |
| KIF2C | kinesin family member 2C | 0.017404 |
| TUBA1C | tubulin, alpha 1c | 0.0173974 |
| CCN2 | cellular communication network factor 2 | 0.0173096 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0172099 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0171819 |
| KIF11 | kinesin family member 11 | 0.0170833 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0167806 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.016742 |
| CALR | calreticulin | 0.0165493 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0164463 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.016428 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.016421 |
| TJP1 | tight junction protein 1 | 0.0164032 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0161986 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0161263 |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.0160736 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0160391 |
| NKTR | natural killer cell triggering receptor | 0.0158863 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0158436 |
| RPS7 | ribosomal protein S7 | 0.0157092 |
| TPM3 | tropomyosin 3 | 0.0156944 |
| VMP1 | vacuole membrane protein 1 | 0.0156924 |
| DNAJC21 | DnaJ (Hsp40) homolog, subfamily C, member 21 | 0.0156597 |
| KIF18B | kinesin family member 18B | 0.0156386 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.015576 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0155545 |
| NUP58 | nucleoporin 58 | 0.0154888 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0154396 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0154103 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0152739 |
| EFNA5 | ephrin-A5 | 0.0152636 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0152103 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0151699 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.015081 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0150316 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0149469 |
| RUNX1 | runt-related transcription factor 1 | 0.0148291 |
| FOXM1 | forkhead box M1 | 0.0147712 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0147025 |
| DUSP6 | dual specificity phosphatase 6 | 0.0146901 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0146614 |
| CEP70 | centrosomal protein 70kDa | 0.0144775 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0144316 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.393486 |
| MMP12 | matrix metallopeptidase 12 | -0.149469 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.126914 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.115962 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.100227 |
| AHNAK | AHNAK nucleoprotein | -0.0951089 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0871886 |
| EHBP1 | EH domain binding protein 1 | -0.0781778 |
| ACTG1 | actin gamma 1 | -0.0779849 |
| RPL35A | ribosomal protein L35a | -0.0737589 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.066522 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0656137 |
| CLDN1 | claudin 1 | -0.0627873 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0626981 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0623161 |
| VIM | vimentin | -0.0619461 |
| HMGA2 | high mobility group AT-hook 2 | -0.0599776 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0593185 |
| ASPH | aspartate beta-hydroxylase | -0.0572871 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.055807 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0556234 |
| NHSL1 | NHS-like 1 | -0.0546456 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.053482 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0532491 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0522263 |
| ZNF217 | zinc finger protein 217 | -0.0498228 |
| TXNRD1 | thioredoxin reductase 1 | -0.0473301 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0457265 |
| UBC | ubiquitin C | -0.0455471 |
| RPS6 | ribosomal protein S6 | -0.0448285 |
| RPL34 | ribosomal protein L34 | -0.0448217 |
| BCHE | butyrylcholinesterase | -0.0444847 |
| FBXO11 | F-box protein 11 | -0.0439962 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0437559 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0434161 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0430875 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0424393 |
| MGAT4C | MGAT4 family, member C | -0.041862 |
| RAB10 | RAB10, member RAS oncogene family | -0.041686 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0414521 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0412864 |
| S100A10 | S100 calcium binding protein A10 | -0.0404552 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0404057 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0403068 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0403053 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0381026 |
| TMEM123 | transmembrane protein 123 | -0.0380259 |
| ANXA1 | annexin A1 | -0.0379401 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0369218 |
| JMJD1C | jumonji domain containing 1C | -0.0365423 |
| GNAS | GNAS complex locus | -0.035982 |
| LMO7 | LIM domain 7 | -0.0357636 |
| PCDH7 | protocadherin 7 | -0.0356838 |
| ZNF804A | zinc finger protein 804A | -0.0354882 |
| USP53 | ubiquitin specific peptidase 53 | -0.0353693 |
| SLC38A1 | solute carrier family 38, member 1 | -0.035279 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0351074 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0338832 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0334392 |
| CANX | calnexin | -0.0329383 |
| S100A6 | S100 calcium binding protein A6 | -0.0323479 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0322959 |
| PGK1 | phosphoglycerate kinase 1 | -0.0320479 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0318409 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0315384 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0314884 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0308796 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0308421 |
| RASAL2 | RAS protein activator like 2 | -0.0307922 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0304047 |
| RTN3 | reticulon 3 | -0.030129 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0300492 |
| RPL23 | ribosomal protein L23 | -0.02989 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0298625 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0296432 |
| CDK12 | cyclin-dependent kinase 12 | -0.0291868 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0290735 |
| NABP1 | nucleic acid binding protein 1 | -0.0289951 |
| RPLP1 | ribosomal protein, large, P1 | -0.0287117 |
| RPL38 | ribosomal protein L38 | -0.0286153 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0285888 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.028304 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0282752 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0282407 |
| TUBB | tubulin, beta class I | -0.0280134 |
| DST | dystonin | -0.0279816 |
| TMSB10 | thymosin beta 10 | -0.0279221 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0278013 |
| RPL32 | ribosomal protein L32 | -0.027787 |
| NF1 | neurofibromin 1 | -0.0273131 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0271169 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0270431 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0269469 |
| GASK1B | golgi associated kinase 1B | -0.026699 |
| RPLP0 | ribosomal protein, large, P0 | -0.0265271 |
| H1-0 | H1.0 linker histone | -0.0263291 |
| RBM39 | RNA binding motif protein 39 | -0.0263153 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0262629 |
| CDC42SE2 | CDC42 small effector 2 | -0.0261202 |
| CCDC47 | coiled-coil domain containing 47 | -0.0259465 |
