| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Trifluridine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0640076 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0584171 |
| VMP1 | vacuole membrane protein 1 | 0.0546169 |
| VCL | vinculin | 0.0458626 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0442659 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0442205 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0381408 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0381314 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0368919 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0346062 |
| PRKCA | protein kinase C, alpha | 0.0331784 |
| R3HDM2 | R3H domain containing 2 | 0.0331591 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.032991 |
| RNF213 | ring finger protein 213 | 0.0324854 |
| PLPP1 | phospholipid phosphatase 1 | 0.0316364 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0312012 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0310746 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0307596 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0304579 |
| BPTF | bromodomain PHD finger transcription factor | 0.0304081 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0287049 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0282136 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0281189 |
| TLE4 | transducin-like enhancer of split 4 | 0.028099 |
| EFNA5 | ephrin-A5 | 0.0278407 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0274091 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0273121 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0270897 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0269641 |
| DACH2 | dachshund family transcription factor 2 | 0.0259886 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0257632 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0251563 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0247236 |
| CADM2 | cell adhesion molecule 2 | 0.024442 |
| RPS27 | ribosomal protein S27 | 0.0243837 |
| SYT1 | synaptotagmin I | 0.0243245 |
| GSE1 | Gse1 coiled-coil protein | 0.0241958 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0236543 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0236141 |
| EGR1 | early growth response 1 | 0.0236037 |
| CNTN4 | contactin 4 | 0.0232711 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0230977 |
| MYO9A | myosin IXA | 0.023082 |
| RPS3 | ribosomal protein S3 | 0.0229166 |
| PCDH15 | protocadherin-related 15 | 0.0226846 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.02268 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0226634 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0224595 |
| RGS4 | regulator of G-protein signaling 4 | 0.0224277 |
| FN1 | fibronectin 1 | 0.0224038 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0223973 |
| VCAN | versican | 0.0215214 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0214759 |
| PTEN | phosphatase and tensin homolog | 0.0207971 |
| MCL1 | myeloid cell leukemia 1 | 0.0205695 |
| TPM4 | tropomyosin 4 | 0.0205564 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0204247 |
| EXOC4 | exocyst complex component 4 | 0.0203308 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0200102 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0199424 |
| RPS7 | ribosomal protein S7 | 0.0198858 |
| MYO6 | myosin VI | 0.0198312 |
| CXXC5 | CXXC finger protein 5 | 0.0197066 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0196941 |
| PMP22 | peripheral myelin protein 22 | 0.0196709 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0195144 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0195133 |
| TENM4 | teneurin transmembrane protein 4 | 0.0193548 |
| YBX3 | Y box binding protein 3 | 0.0193202 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0188191 |
| DNM3 | dynamin 3 | 0.0188122 |
| RACK1 | receptor for activated C kinase 1 | 0.0185214 |
| SYTL3 | synaptotagmin-like 3 | 0.0184348 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.0182266 |
| KIF26B | kinesin family member 26B | 0.0182121 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.018212 |
| ITGAV | integrin, alpha V | 0.0180612 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0180514 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0178993 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0176887 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0176641 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0176257 |
| KLF6 | Kruppel-like factor 6 | 0.0174422 |
| PALLD | palladin, cytoskeletal associated protein | 0.0174292 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0173311 |
| SIK2 | salt-inducible kinase 2 | 0.016624 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0166091 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0165529 |
| PHF14 | PHD finger protein 14 | 0.0164703 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0164503 |
| TBX2 | T-box 2 | 0.0164349 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0163483 |
| GATA3 | GATA binding protein 3 | 0.0163332 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | 0.0162891 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0161682 |
| RAD51B | RAD51 paralog B | 0.0160281 |
| FTL | ferritin, light polypeptide | 0.0159431 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.015934 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0157848 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0157755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.235867 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.235064 |
| PTMA | prothymosin, alpha | -0.106049 |
| COL1A1 | collagen, type I, alpha 1 | -0.0967086 |
| HELZ | helicase with zinc finger | -0.0834813 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0827402 |
| ACTG1 | actin gamma 1 | -0.0786405 |
| COL3A1 | collagen, type III, alpha 1 | -0.0669465 |
| RPL35A | ribosomal protein L35a | -0.0635744 |
| LPIN1 | lipin 1 | -0.0540792 |
| SPAG9 | sperm associated antigen 9 | -0.0528768 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0519894 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0513136 |
| IGF2 | insulin-like growth factor 2 | -0.0512973 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0508069 |
| FAM13A | family with sequence similarity 13, member A | -0.0477269 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0468125 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0467269 |
| CENPF | centromere protein F, 350/400kDa | -0.0462917 |
| RPL38 | ribosomal protein L38 | -0.0462763 |
| MEIS2 | Meis homeobox 2 | -0.0462045 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0456447 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0450887 |
| AHNAK | AHNAK nucleoprotein | -0.0445814 |
| NF1 | neurofibromin 1 | -0.0442404 |
| VIM | vimentin | -0.0434667 |
| CLTC | clathrin, heavy chain (Hc) | -0.0427462 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0422064 |
| RPL19 | ribosomal protein L19 | -0.0419328 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0412249 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0401756 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0392679 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0391411 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0378057 |
| DST | dystonin | -0.0368788 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0362923 |
| SETD5 | SET domain containing 5 | -0.0358438 |
| APP | amyloid beta (A4) precursor protein | -0.0353503 |
| CANX | calnexin | -0.03515 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0351422 |
| RPLP1 | ribosomal protein, large, P1 | -0.0351205 |
| UBC | ubiquitin C | -0.035096 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0350753 |
| CCDC47 | coiled-coil domain containing 47 | -0.034683 |
| ADAR | adenosine deaminase, RNA-specific | -0.0345121 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0341372 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0334921 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0334449 |
| TMSB10 | thymosin beta 10 | -0.0329583 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0328195 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0327293 |
| GLG1 | golgi glycoprotein 1 | -0.0323869 |
| MED13 | mediator complex subunit 13 | -0.0323121 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0321358 |
| RPS6 | ribosomal protein S6 | -0.0320527 |
| TPR | translocated promoter region, nuclear basket protein | -0.0314783 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.031238 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.031217 |
| PHIP | pleckstrin homology domain interacting protein | -0.0308587 |
| RBMX | RNA binding motif protein, X-linked | -0.0306161 |
| PGK1 | phosphoglycerate kinase 1 | -0.0305571 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0302239 |
| CCND1 | cyclin D1 | -0.0301796 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.029763 |
| ZNF292 | zinc finger protein 292 | -0.0297185 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0297091 |
| RPL34 | ribosomal protein L34 | -0.0296876 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0293376 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0293252 |
| NRG1 | neuregulin 1 | -0.0291273 |
| NCOR1 | nuclear receptor corepressor 1 | -0.028908 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.028851 |
| RO60 | Ro60, Y RNA binding protein | -0.0288441 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0288364 |
| WDR45B | WD repeat domain 45B | -0.0287117 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0285596 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0282888 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0280577 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0278715 |
| KLHL13 | kelch-like family member 13 | -0.0278094 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0277678 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0277127 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0273497 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0272982 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0270202 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0268895 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0266198 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0266014 |
| AOPEP | aminopeptidase O (putative) | -0.0265551 |
| CASC3 | cancer susceptibility candidate 3 | -0.0262468 |
| RPL7A | ribosomal protein L7a | -0.0261461 |
| GNAS | GNAS complex locus | -0.0261419 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0259729 |
| FNBP1 | formin binding protein 1 | -0.0259469 |
| TULP4 | tubby like protein 4 | -0.0259267 |
| RPL32 | ribosomal protein L32 | -0.0257982 |
| MKI67 | marker of proliferation Ki-67 | -0.0257017 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0256697 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0252991 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0252508 |