| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.247086 |
| MACC1 | metastasis associated in colon cancer 1 | 0.155096 |
| LCN2 | lipocalin 2 | 0.132773 |
| B2M | beta-2-microglobulin | 0.124426 |
| MYO1E | myosin IE | 0.116448 |
| ANXA2 | annexin A2 | 0.0958591 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0944462 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0918859 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0709692 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0686423 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0654338 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0618291 |
| AREG | amphiregulin | 0.0600709 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0574111 |
| EFNB2 | ephrin-B2 | 0.0569526 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0564773 |
| RUNX1 | runt-related transcription factor 1 | 0.0509442 |
| KLF6 | Kruppel-like factor 6 | 0.0506171 |
| NEBL | nebulette | 0.0475553 |
| PERP | PERP, TP53 apoptosis effector | 0.0463524 |
| TJP1 | tight junction protein 1 | 0.0447701 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0435897 |
| EREG | epiregulin | 0.0432206 |
| CLDN4 | claudin 4 | 0.0424023 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0423814 |
| SQSTM1 | sequestosome 1 | 0.042063 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0420337 |
| TXNRD1 | thioredoxin reductase 1 | 0.0406219 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0405913 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0403731 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0398652 |
| ENO1 | enolase 1, (alpha) | 0.0386639 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0385853 |
| DSPP | dentin sialophosphoprotein | 0.0376946 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0373128 |
| VMP1 | vacuole membrane protein 1 | 0.037097 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0369706 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0364256 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0354365 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0353863 |
| MX2 | MX dynamin-like GTPase 2 | 0.0346472 |
| FTL | ferritin, light polypeptide | 0.0341183 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0337204 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0337042 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0336739 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0336372 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0325407 |
| IFNGR1 | interferon gamma receptor 1 | 0.0324958 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0314907 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0314881 |
| ZNF292 | zinc finger protein 292 | 0.0313397 |
| DUSP16 | dual specificity phosphatase 16 | 0.0310723 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0305263 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0304978 |
| HKDC1 | hexokinase domain containing 1 | 0.0304478 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0301265 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0296115 |
| PRSS3 | protease, serine, 3 | 0.0287989 |
| USP54 | ubiquitin specific peptidase 54 | 0.028673 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0286547 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0282882 |
| LIMA1 | LIM domain and actin binding 1 | 0.0282534 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0281101 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0280842 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0279225 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0274488 |
| LDHA | lactate dehydrogenase A | 0.0274301 |
| ITGA6 | integrin, alpha 6 | 0.0273181 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0270127 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.026592 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0265429 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0264079 |
| BCL2L1 | BCL2-like 1 | 0.0259219 |
| HLA-A | major histocompatibility complex, class I, A | 0.025513 |
| SLK | STE20-like kinase | 0.025415 |
| RPS3 | ribosomal protein S3 | 0.0251137 |
| DST | dystonin | 0.0249569 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0243599 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0242741 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0235196 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0235137 |
| TES | testin LIM domain protein | 0.0231217 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0230851 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.02308 |
| ETV6 | ets variant 6 | 0.0230736 |
| YBX3 | Y box binding protein 3 | 0.023039 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0229141 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | 0.0226329 |
| IRS2 | insulin receptor substrate 2 | 0.0225112 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0224418 |
| EHF | ets homologous factor | 0.0222863 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0220072 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0219346 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0217394 |
| ITGB8 | integrin, beta 8 | 0.0214376 |
| LAMC2 | laminin, gamma 2 | 0.0214158 |
| NTN4 | netrin 4 | 0.0211246 |
| MEIS2 | Meis homeobox 2 | 0.0210705 |
| FAT1 | FAT atypical cadherin 1 | 0.0210469 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0210326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LYZ | lysozyme | -0.237181 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.166319 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.127792 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.105944 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.103034 |
| RPL35A | ribosomal protein L35a | -0.0836654 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0823551 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0716186 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0698559 |
| PTMA | prothymosin, alpha | -0.0692408 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0690577 |
| RAD51B | RAD51 paralog B | -0.0680278 |
| NPSR1 | neuropeptide S receptor 1 | -0.0671952 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0651467 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0644205 |
| XAF1 | XIAP associated factor 1 | -0.0631949 |
| PRKCA | protein kinase C, alpha | -0.0602046 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0592426 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0570743 |
| RPL34 | ribosomal protein L34 | -0.054699 |
| RIGI | RNA sensor RIG-I | -0.0544529 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0542531 |
| INTS6 | integrator complex subunit 6 | -0.0503879 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0484594 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0476174 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0458011 |
| ACTG1 | actin gamma 1 | -0.0451236 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0450346 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0449528 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0447195 |
| TXNIP | thioredoxin interacting protein | -0.0438421 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.043803 |
| ZNF609 | zinc finger protein 609 | -0.0435553 |
| HLA-B | major histocompatibility complex, class I, B | -0.043198 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0429785 |
| SSH2 | slingshot protein phosphatase 2 | -0.0422308 |
| TNS4 | tensin 4 | -0.0417568 |
| PLSCR2 | phospholipid scramblase 2 | -0.0410259 |
| MAP7 | microtubule-associated protein 7 | -0.0407112 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0393733 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0392862 |
| ATXN1 | ataxin 1 | -0.038561 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0380973 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0380222 |
| EPHB2 | EPH receptor B2 | -0.0373029 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0367694 |
| NF1 | neurofibromin 1 | -0.0363932 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0359351 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0354879 |
| UBC | ubiquitin C | -0.0343377 |
| PTK2 | protein tyrosine kinase 2 | -0.0343167 |
| ASPH | aspartate beta-hydroxylase | -0.0341836 |
| PLSCR1 | phospholipid scramblase 1 | -0.0328612 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0327775 |
| SP100 | SP100 nuclear antigen | -0.0323397 |
| DENND1A | DENN/MADD domain containing 1A | -0.0310804 |
| RPS6 | ribosomal protein S6 | -0.0309694 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0306304 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0302248 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0297692 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0293036 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0292483 |
| POU2F2 | POU class 2 homeobox 2 | -0.0290998 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0289082 |
| MX1 | MX dynamin-like GTPase 1 | -0.0288455 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0285056 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.028363 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0283497 |
| MED13L | mediator complex subunit 13-like | -0.0282216 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0279836 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0279139 |
| TAOK3 | TAO kinase 3 | -0.0278678 |
| APOL6 | apolipoprotein L, 6 | -0.0278676 |
| CANX | calnexin | -0.0275795 |
| PMP22 | peripheral myelin protein 22 | -0.0273822 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0273618 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0272696 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0270799 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0269727 |
| CUX1 | cut-like homeobox 1 | -0.0267469 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0266471 |
| PHF20 | PHD finger protein 20 | -0.0265094 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0263866 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.026189 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0261262 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0259998 |
| PHF3 | PHD finger protein 3 | -0.0259839 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0258689 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0257555 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0256317 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0254169 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0251731 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0250548 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0248312 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0244051 |
| NUMB | numb homolog (Drosophila) | -0.0239451 |
| PTGR1 | prostaglandin reductase 1 | -0.0238287 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0236595 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0235666 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.023516 |
