| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Trifluridine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.125919 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0846157 |
| RPS12 | ribosomal protein S12 | 0.0729754 |
| B2M | beta-2-microglobulin | 0.0726528 |
| RPS3 | ribosomal protein S3 | 0.0716815 |
| MT2A | metallothionein 2A | 0.0705565 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0639777 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0627711 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0615404 |
| ASPH | aspartate beta-hydroxylase | 0.058132 |
| LDHA | lactate dehydrogenase A | 0.0533335 |
| RPS8 | ribosomal protein S8 | 0.0528808 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0516524 |
| FTL | ferritin, light polypeptide | 0.0508472 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.050692 |
| MKI67 | marker of proliferation Ki-67 | 0.048987 |
| TXNRD1 | thioredoxin reductase 1 | 0.0464182 |
| ANXA1 | annexin A1 | 0.0457824 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0444231 |
| HLA-E | major histocompatibility complex, class I, E | 0.0437357 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0403999 |
| EFNA5 | ephrin-A5 | 0.0392189 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0388756 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0369775 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.036716 |
| HMGA2 | high mobility group AT-hook 2 | 0.0361547 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0351595 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0342172 |
| ENO1 | enolase 1, (alpha) | 0.0338067 |
| SIK3 | SIK family kinase 3 | 0.0337899 |
| TPM3 | tropomyosin 3 | 0.0336711 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0331026 |
| SEPTIN7 | septin 7 | 0.0328689 |
| FOXP1 | forkhead box P1 | 0.0328135 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0327221 |
| RACK1 | receptor for activated C kinase 1 | 0.0319219 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0318097 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0309897 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0308275 |
| SULF2 | sulfatase 2 | 0.0305685 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0305365 |
| TOP1 | topoisomerase (DNA) I | 0.0303698 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0297173 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0296009 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0294967 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0294398 |
| MT1E | metallothionein 1E | 0.0294006 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0292164 |
| RPS2 | ribosomal protein S2 | 0.0291371 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0290769 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0286259 |
| RPL37A | ribosomal protein L37a | 0.0279215 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0277519 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0276405 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0275882 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0275392 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0275232 |
| RPS17 | ribosomal protein S17 | 0.0272592 |
| PHF14 | PHD finger protein 14 | 0.0270552 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0269704 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0264154 |
| RPL31 | ribosomal protein L31 | 0.0260428 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0255338 |
| CLU | clusterin | 0.0255302 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0253306 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0252425 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0251969 |
| RPS25 | ribosomal protein S25 | 0.0250624 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0247382 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0247007 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0244045 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0242758 |
| RPL9 | ribosomal protein L9 | 0.0242706 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0241081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0237783 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0237463 |
| CENPF | centromere protein F, 350/400kDa | 0.0235952 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0233652 |
| JAG1 | jagged 1 | 0.0232247 |
| CLSPN | claspin | 0.0231342 |
| E2F7 | E2F transcription factor 7 | 0.0228575 |
| RPLP2 | ribosomal protein, large, P2 | 0.0226892 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0226462 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0223888 |
| RPL21 | ribosomal protein L21 | 0.0223862 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.022379 |
| TPR | translocated promoter region, nuclear basket protein | 0.0223396 |
| RPL37 | ribosomal protein L37 | 0.0223162 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0221464 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0221365 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.021969 |
| TXNIP | thioredoxin interacting protein | 0.0217454 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0214814 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0213547 |
| ERBIN | erbb2 interacting protein | 0.0212202 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.0211634 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0211523 |
| RPS7 | ribosomal protein S7 | 0.0211068 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0210817 |
| PMP22 | peripheral myelin protein 22 | 0.0208603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.22128 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190504 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.163551 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.113203 |
| AHNAK | AHNAK nucleoprotein | -0.108756 |
| SULF1 | sulfatase 1 | -0.0937154 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0858942 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0853078 |
| NDRG1 | N-myc downstream regulated 1 | -0.0836084 |
| S100A10 | S100 calcium binding protein A10 | -0.0820636 |
| PALLD | palladin, cytoskeletal associated protein | -0.0806063 |
| RBM39 | RNA binding motif protein 39 | -0.0787379 |
| EMP1 | epithelial membrane protein 1 | -0.0738329 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0715949 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0705744 |
| TMSB4X | thymosin beta 4, X-linked | -0.0684631 |
| H1-0 | H1.0 linker histone | -0.0643408 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0641391 |
| POTEF | POTE ankyrin domain family, member F | -0.0625769 |
| EFHD2 | EF-hand domain family, member D2 | -0.0583462 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.057543 |
| PLS3 | plastin 3 | -0.0566375 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0548801 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0531396 |
| RPS21 | ribosomal protein S21 | -0.0524335 |
| KRT17 | keratin 17, type I | -0.0511391 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0508414 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.050081 |
| VCL | vinculin | -0.0499614 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0492364 |
| FOXO1 | forkhead box O1 | -0.0471237 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0470505 |
| RPL34 | ribosomal protein L34 | -0.0469119 |
| GOLGA4 | golgin A4 | -0.0466746 |
| NEK7 | NIMA-related kinase 7 | -0.0458876 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0452589 |
| ANKRD33B | ankyrin repeat domain 33B | -0.045088 |
| ACTN4 | actinin, alpha 4 | -0.0444948 |
| WASF2 | WAS protein family, member 2 | -0.044377 |
| CANX | calnexin | -0.043928 |
| HM13 | histocompatibility (minor) 13 | -0.0423063 |
| CUL4B | cullin 4B | -0.0418103 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0409701 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0404396 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0394866 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0390474 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.038407 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0374665 |
| SERTAD2 | SERTA domain containing 2 | -0.0365661 |
| PLEC | plectin | -0.0364528 |
| UBC | ubiquitin C | -0.0363783 |
| GLG1 | golgi glycoprotein 1 | -0.0360999 |
| OSMR | oncostatin M receptor | -0.0355392 |
| RPL35A | ribosomal protein L35a | -0.0352985 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0350053 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0346902 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0345175 |
| ACTG1 | actin gamma 1 | -0.0344032 |
| PGK1 | phosphoglycerate kinase 1 | -0.0342929 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0340799 |
| BLCAP | bladder cancer associated protein | -0.0340717 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0339605 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0334479 |
| SBF2 | SET binding factor 2 | -0.0333839 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0325433 |
| RPL8 | ribosomal protein L8 | -0.0324916 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0324126 |
| KIAA1217 | KIAA1217 | -0.0323442 |
| RPS6 | ribosomal protein S6 | -0.032102 |
| DSG2 | desmoglein 2 | -0.0320784 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.032006 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0317537 |
| SLC45A4 | solute carrier family 45, member 4 | -0.031616 |
| RASAL2 | RAS protein activator like 2 | -0.0315663 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0313716 |
| CD99 | CD99 molecule | -0.0313709 |
| NRG1 | neuregulin 1 | -0.0311083 |
| TMSB10 | thymosin beta 10 | -0.0310696 |
| RPS11 | ribosomal protein S11 | -0.0308638 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0307525 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0304406 |
| LDLR | low density lipoprotein receptor | -0.0298717 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0298125 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0297932 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.0293884 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0291657 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0290804 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0287165 |
| OGA | O-GlcNAcase | -0.0286671 |
| TMEM263 | transmembrane protein 263 | -0.0285715 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0284895 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0283935 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0282172 |
| TMEM123 | transmembrane protein 123 | -0.028185 |
| FRMD5 | FERM domain containing 5 | -0.0279 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | -0.0274067 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0271787 |
| ATF4 | activating transcription factor 4 | -0.02693 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0269068 |
| LMO7 | LIM domain 7 | -0.0268357 |
