| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Trifluridine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.289644 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.177069 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.103181 |
| LCN2 | lipocalin 2 | 0.0915294 |
| ITGA6 | integrin, alpha 6 | 0.0906447 |
| PTMA | prothymosin, alpha | 0.0807445 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0787109 |
| B2M | beta-2-microglobulin | 0.0755836 |
| EZR | ezrin | 0.0718136 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0658586 |
| TMSB10 | thymosin beta 10 | 0.0640248 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.063276 |
| RPS3 | ribosomal protein S3 | 0.0616211 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0568582 |
| RPS12 | ribosomal protein S12 | 0.0541597 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0537688 |
| ASPH | aspartate beta-hydroxylase | 0.0523022 |
| CLDN4 | claudin 4 | 0.0506315 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0505075 |
| KRT18 | keratin 18, type I | 0.0504556 |
| ENO1 | enolase 1, (alpha) | 0.0494587 |
| ANXA2 | annexin A2 | 0.0488121 |
| ANXA1 | annexin A1 | 0.0488067 |
| LMNA | lamin A/C | 0.0484025 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0454835 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0433472 |
| EHBP1 | EH domain binding protein 1 | 0.0391381 |
| ATF5 | activating transcription factor 5 | 0.039095 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0385127 |
| LIMA1 | LIM domain and actin binding 1 | 0.03736 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0360802 |
| RPS8 | ribosomal protein S8 | 0.035628 |
| EFNA5 | ephrin-A5 | 0.0354355 |
| SET | SET nuclear proto-oncogene | 0.0352743 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0347966 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0345112 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0344728 |
| CBX3 | chromobox homolog 3 | 0.0344358 |
| PFN1 | profilin 1 | 0.0342943 |
| KRT19 | keratin 19, type I | 0.0342172 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0340478 |
| BCL2L1 | BCL2-like 1 | 0.0339864 |
| CD9 | CD9 molecule | 0.0336754 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0329275 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0326411 |
| MYADM | myeloid-associated differentiation marker | 0.0323067 |
| HLA-A | major histocompatibility complex, class I, A | 0.0322336 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0316626 |
| HMGA1 | high mobility group AT-hook 1 | 0.0312565 |
| TUBA1B | tubulin, alpha 1b | 0.0312459 |
| KLK10 | kallikrein-related peptidase 10 | 0.030673 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0303174 |
| LAMA4 | laminin, alpha 4 | 0.0302508 |
| S100A6 | S100 calcium binding protein A6 | 0.0301271 |
| GDA | guanine deaminase | 0.0299099 |
| AGR3 | anterior gradient 3 | 0.0297767 |
| DSTN | destrin (actin depolymerizing factor) | 0.0297193 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0295513 |
| SLTM | SAFB-like, transcription modulator | 0.0295082 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0291464 |
| TPM3 | tropomyosin 3 | 0.0288858 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0288092 |
| AREG | amphiregulin | 0.0284254 |
| RPS17 | ribosomal protein S17 | 0.0283344 |
| S100A11 | S100 calcium binding protein A11 | 0.0277292 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0276566 |
| KLF6 | Kruppel-like factor 6 | 0.0274299 |
| RRM2 | ribonucleotide reductase M2 | 0.027303 |
| TPI1 | triosephosphate isomerase 1 | 0.0262889 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0262753 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0261827 |
| LDHA | lactate dehydrogenase A | 0.0261264 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.025883 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0258797 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0257928 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.0255421 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0252667 |
| S100A9 | S100 calcium binding protein A9 | 0.0252636 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0250814 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0247479 |
| HMGB2 | high mobility group box 2 | 0.0246802 |
| EGR1 | early growth response 1 | 0.0246801 |
| RPL26 | ribosomal protein L26 | 0.0243552 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0242157 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0239739 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.023834 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0236833 |
| TMC5 | transmembrane channel-like 5 | 0.0234347 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0233036 |
| MT2A | metallothionein 2A | 0.0231342 |
| RPS7 | ribosomal protein S7 | 0.0230455 |
| COX6C | cytochrome c oxidase subunit VIc | 0.023034 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.0229033 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.022866 |
| JUP | junction plakoglobin | 0.0227226 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0226658 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0225466 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.022408 |
| MKI67 | marker of proliferation Ki-67 | 0.0223826 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0223061 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.279384 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.173219 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117974 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.101693 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0798495 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0763512 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0685257 |
| AGR2 | anterior gradient 2 | -0.0658602 |
| UBC | ubiquitin C | -0.0638321 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0620395 |
| GOLGA4 | golgin A4 | -0.0596398 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0594077 |
| H1-0 | H1.0 linker histone | -0.0585988 |
| AHNAK | AHNAK nucleoprotein | -0.0578866 |
| CD2AP | CD2-associated protein | -0.0575896 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0555912 |
| LOC112694756 | uncharaterized LOC112694756 | -0.053609 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0519794 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0513375 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0479891 |
| CANX | calnexin | -0.0471802 |
| RRBP1 | ribosome binding protein 1 | -0.0459094 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0456918 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0453103 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.04432 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0432606 |
| RBM39 | RNA binding motif protein 39 | -0.0426194 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0425532 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0418615 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0415878 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0398481 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0398091 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0397861 |
| HDLBP | high density lipoprotein binding protein | -0.0390719 |
| COG5 | component of oligomeric golgi complex 5 | -0.0387245 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0384778 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0383664 |
| GOLGB1 | golgin B1 | -0.0379776 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0373231 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0365459 |
| ACTG1 | actin gamma 1 | -0.0363964 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0359121 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0355741 |
| ARCN1 | archain 1 | -0.0351954 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0351689 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0344329 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0343997 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0343181 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0342526 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0339691 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0327192 |
| WDR45B | WD repeat domain 45B | -0.0324789 |
| CDK13 | cyclin-dependent kinase 13 | -0.0324354 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0322357 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0317789 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0316455 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.031419 |
| S100A10 | S100 calcium binding protein A10 | -0.0312538 |
| PMM2 | phosphomannomutase 2 | -0.0311588 |
| RPL35A | ribosomal protein L35a | -0.0309257 |
| NDRG1 | N-myc downstream regulated 1 | -0.0303957 |
| ATM | ATM serine/threonine kinase | -0.0288978 |
| COPA | coatomer protein complex, subunit alpha | -0.0281273 |
| HLA-E | major histocompatibility complex, class I, E | -0.0280461 |
| COG6 | component of oligomeric golgi complex 6 | -0.0276992 |
| HLA-C | major histocompatibility complex, class I, C | -0.0276716 |
| KLHL29 | kelch-like family member 29 | -0.0275937 |
| INSIG1 | insulin induced gene 1 | -0.0275599 |
| SPAG9 | sperm associated antigen 9 | -0.0273282 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0270628 |
| KRT8 | keratin 8, type II | -0.0269597 |
| RTN3 | reticulon 3 | -0.026932 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0268872 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0267521 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0266691 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0265751 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0264279 |
| RPL8 | ribosomal protein L8 | -0.0258125 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0257178 |
| STK24 | serine/threonine kinase 24 | -0.0255424 |
| SEC24D | SEC24 family member D | -0.025369 |
| GLG1 | golgi glycoprotein 1 | -0.0252174 |
| FNIP1 | folliculin interacting protein 1 | -0.0250732 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0250489 |
| USO1 | USO1 vesicle transport factor | -0.0248531 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0247451 |
| RSF1 | remodeling and spacing factor 1 | -0.0244328 |
| TXNRD1 | thioredoxin reductase 1 | -0.0243716 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0242187 |
| GPX2 | glutathione peroxidase 2 | -0.0241857 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0241678 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0240034 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0239909 |
| TMSB4X | thymosin beta 4, X-linked | -0.0238798 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0238499 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0236984 |
| AFTPH | aftiphilin | -0.0236545 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0234474 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0234173 |
| PUM2 | pumilio RNA-binding family member 2 | -0.023298 |
