| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.153888 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.110616 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0881593 |
| KRT18 | keratin 18, type I | 0.0844213 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0775137 |
| LDHA | lactate dehydrogenase A | 0.0763343 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0644219 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0629255 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0533566 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0512931 |
| TPI1 | triosephosphate isomerase 1 | 0.0495321 |
| PFN1 | profilin 1 | 0.0474359 |
| FAT1 | FAT atypical cadherin 1 | 0.0470496 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.045839 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0426971 |
| MT2A | metallothionein 2A | 0.041498 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0408187 |
| MLEC | malectin | 0.0406425 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0399622 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0398786 |
| RPL18 | ribosomal protein L18 | 0.0395463 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0392891 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0359749 |
| MUC17 | mucin 17, cell surface associated | 0.0358773 |
| FTL | ferritin, light polypeptide | 0.0355253 |
| SON | SON DNA binding protein | 0.0351688 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0344833 |
| TUBA1B | tubulin, alpha 1b | 0.0342043 |
| FOXP1 | forkhead box P1 | 0.0328745 |
| ITGA6 | integrin, alpha 6 | 0.0328148 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0327612 |
| KRT19 | keratin 19, type I | 0.0322713 |
| CBX3 | chromobox homolog 3 | 0.0317758 |
| CADPS | Ca++-dependent secretion activator | 0.0316647 |
| HMGA1 | high mobility group AT-hook 1 | 0.0314976 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0312831 |
| RPS12 | ribosomal protein S12 | 0.0312773 |
| PERP | PERP, TP53 apoptosis effector | 0.0312574 |
| MT1E | metallothionein 1E | 0.0304687 |
| RPLP0 | ribosomal protein, large, P0 | 0.0302767 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0301734 |
| RPS2 | ribosomal protein S2 | 0.0293408 |
| HMGB2 | high mobility group box 2 | 0.0292263 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0290448 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0289783 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0287185 |
| LMO7 | LIM domain 7 | 0.0284595 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0280956 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0273364 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0262891 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.02613 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0260898 |
| ABHD2 | abhydrolase domain containing 2 | 0.0260347 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0257722 |
| S100A6 | S100 calcium binding protein A6 | 0.0253022 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0248217 |
| USP6NL | USP6 N-terminal like | 0.0248126 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0241448 |
| TPM3 | tropomyosin 3 | 0.0240006 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0237737 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0231264 |
| ENO1 | enolase 1, (alpha) | 0.022886 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0228438 |
| TAGLN2 | transgelin 2 | 0.0226461 |
| TNS4 | tensin 4 | 0.0225154 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0224836 |
| SERINC5 | serine incorporator 5 | 0.0222993 |
| KLK10 | kallikrein-related peptidase 10 | 0.0221023 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0219826 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0219812 |
| PRDX1 | peroxiredoxin 1 | 0.0219647 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0218419 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0214263 |
| TXN2 | thioredoxin 2 | 0.0204834 |
| ABHD17C | abhydrolase domain containing 17C | 0.0203724 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.020279 |
| CLDN7 | claudin 7 | 0.0202611 |
| RPL21 | ribosomal protein L21 | 0.0202556 |
| RRM2 | ribonucleotide reductase M2 | 0.0201931 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0201203 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0199919 |
| CLIC1 | chloride intracellular channel 1 | 0.0198931 |
| FANCI | Fanconi anemia, complementation group I | 0.019569 |
| RPS7 | ribosomal protein S7 | 0.0195684 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0194816 |
| RPL7 | ribosomal protein L7 | 0.0193533 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0192851 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0192743 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0191482 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0191252 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0188443 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0188261 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.0187602 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0187137 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0186054 |
| KLF6 | Kruppel-like factor 6 | 0.0185041 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.018453 |
| RPL35 | ribosomal protein L35 | 0.0184373 |
| DENND4C | DENN/MADD domain containing 4C | 0.0184055 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0181626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.275828 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.246511 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.166492 |
| VCL | vinculin | -0.138818 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134867 |
| RPL35A | ribosomal protein L35a | -0.106057 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0976141 |
| AHNAK | AHNAK nucleoprotein | -0.0947065 |
| ACTG1 | actin gamma 1 | -0.0882179 |
| RPS6 | ribosomal protein S6 | -0.0792185 |
| RPL34 | ribosomal protein L34 | -0.0705669 |
| RPS27A | ribosomal protein S27a | -0.0697531 |
| UBC | ubiquitin C | -0.0696689 |
| PTMA | prothymosin, alpha | -0.0669199 |
| AGR2 | anterior gradient 2 | -0.066785 |
| PIGR | polymeric immunoglobulin receptor | -0.0659052 |
| FLNB | filamin B, beta | -0.0646752 |
| IER3 | immediate early response 3 | -0.0635522 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0620135 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0574934 |
| RPS29 | ribosomal protein S29 | -0.057076 |
| MYO1E | myosin IE | -0.0567652 |
| FBXO11 | F-box protein 11 | -0.0549001 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0548964 |
| GOLGA4 | golgin A4 | -0.0545404 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0539017 |
| RPS23 | ribosomal protein S23 | -0.051895 |
| NDRG1 | N-myc downstream regulated 1 | -0.0513666 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0504964 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0500522 |
| TPM4 | tropomyosin 4 | -0.0484999 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0482785 |
| CALR | calreticulin | -0.0479628 |
| RPS24 | ribosomal protein S24 | -0.0476307 |
| CANX | calnexin | -0.046735 |
| ANKRD11 | ankyrin repeat domain 11 | -0.045652 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0451432 |
| GPHN | gephyrin | -0.0442832 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0440175 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0436013 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0434854 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0432976 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0424311 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0420865 |
| RPL23 | ribosomal protein L23 | -0.0405981 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.040104 |
| NPSR1 | neuropeptide S receptor 1 | -0.0398823 |
| ONECUT3 | one cut homeobox 3 | -0.0394696 |
| RPS11 | ribosomal protein S11 | -0.0394561 |
| RPLP1 | ribosomal protein, large, P1 | -0.0385003 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0384029 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0382338 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0382241 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0379518 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0379152 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0373197 |
| RPL38 | ribosomal protein L38 | -0.0365163 |
| RPL31 | ribosomal protein L31 | -0.0362815 |
| GLG1 | golgi glycoprotein 1 | -0.036153 |
| SETD5 | SET domain containing 5 | -0.0356691 |
| RBM39 | RNA binding motif protein 39 | -0.0356588 |
| S100A10 | S100 calcium binding protein A10 | -0.035549 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0351199 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0348003 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0340733 |
| USP53 | ubiquitin specific peptidase 53 | -0.0340169 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0338188 |
| RPS8 | ribosomal protein S8 | -0.0336846 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0336101 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0334313 |
| CUX1 | cut-like homeobox 1 | -0.0331755 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0325103 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0317681 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0312753 |
| HM13 | histocompatibility (minor) 13 | -0.0312302 |
| PALLD | palladin, cytoskeletal associated protein | -0.0311566 |
| ACTN4 | actinin, alpha 4 | -0.0311092 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0311077 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0308678 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0306586 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0302948 |
| RPL37A | ribosomal protein L37a | -0.0302189 |
| ATXN1 | ataxin 1 | -0.0301394 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0300472 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0297871 |
| INTS6 | integrator complex subunit 6 | -0.0296975 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0294936 |
| TUFT1 | tuftelin 1 | -0.0294237 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0293836 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0292892 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.02911 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0289402 |
| RPLP2 | ribosomal protein, large, P2 | -0.0286271 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0283996 |
| RPS25 | ribosomal protein S25 | -0.0282005 |
| FDPS | farnesyl diphosphate synthase | -0.0280752 |
| SEC24D | SEC24 family member D | -0.0280226 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0278429 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.027814 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0277483 |
