| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.140898 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.131255 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.123447 |
| LOX | lysyl oxidase | 0.116309 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.115226 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.09861 |
| FN1 | fibronectin 1 | 0.0976509 |
| NTN4 | netrin 4 | 0.0946482 |
| ENO1 | enolase 1, (alpha) | 0.0858997 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0851171 |
| CD44 | CD44 molecule (Indian blood group) | 0.0816644 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0750734 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0718726 |
| SYT1 | synaptotagmin I | 0.0712103 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0698931 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0667566 |
| MAP1B | microtubule-associated protein 1B | 0.0662523 |
| ANGPTL4 | angiopoietin-like 4 | 0.0660734 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0660234 |
| FTL | ferritin, light polypeptide | 0.0631916 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0575458 |
| RPS12 | ribosomal protein S12 | 0.0570222 |
| LDHA | lactate dehydrogenase A | 0.0565228 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0553297 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0540744 |
| PLIN2 | perilipin 2 | 0.0539657 |
| HMGA2 | high mobility group AT-hook 2 | 0.0536089 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0514505 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.051407 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0488551 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0480842 |
| NDRG1 | N-myc downstream regulated 1 | 0.0464743 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.046391 |
| SQSTM1 | sequestosome 1 | 0.0452931 |
| B2M | beta-2-microglobulin | 0.0448399 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0443067 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0421205 |
| CA12 | carbonic anhydrase XII | 0.0420788 |
| ANXA2 | annexin A2 | 0.0412219 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0379101 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0374964 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0366359 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0365466 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0361388 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0360199 |
| FAM13A | family with sequence similarity 13, member A | 0.0353139 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0341824 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.033986 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0335915 |
| ADD3 | adducin 3 (gamma) | 0.0331388 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0328717 |
| SYNJ2 | synaptojanin 2 | 0.0325616 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0323663 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0321917 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0320118 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0314195 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0312881 |
| PKM | pyruvate kinase, muscle | 0.0311954 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0293621 |
| DUSP6 | dual specificity phosphatase 6 | 0.0288059 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0286746 |
| S100A6 | S100 calcium binding protein A6 | 0.0286433 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0285689 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0279253 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0278605 |
| HMGA1 | high mobility group AT-hook 1 | 0.0275296 |
| MYADM | myeloid-associated differentiation marker | 0.0273288 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0273099 |
| PRSS23 | protease, serine, 23 | 0.0272305 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0271629 |
| GLCCI1 | glucocorticoid induced 1 | 0.0269659 |
| EGR1 | early growth response 1 | 0.0265159 |
| EREG | epiregulin | 0.0265107 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0264294 |
| KLF6 | Kruppel-like factor 6 | 0.0263644 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0263622 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0261745 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.026145 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0259953 |
| EZR | ezrin | 0.0259414 |
| TOP1 | topoisomerase (DNA) I | 0.025843 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0255741 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0252849 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0252655 |
| KIF13B | kinesin family member 13B | 0.025141 |
| SLTM | SAFB-like, transcription modulator | 0.0249437 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.024642 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0246062 |
| JUN | jun proto-oncogene | 0.0245993 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0245875 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0244806 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0244594 |
| RAI14 | retinoic acid induced 14 | 0.0243592 |
| HLA-A | major histocompatibility complex, class I, A | 0.0242816 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0242021 |
| RPS17 | ribosomal protein S17 | 0.0240189 |
| WLS | wntless Wnt ligand secretion mediator | 0.0236873 |
| KRT19 | keratin 19, type I | 0.0236482 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0235651 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.023367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.202258 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.152818 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.146106 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.119296 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.118815 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.114281 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.11265 |
| NRG1 | neuregulin 1 | -0.0904848 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0856843 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0781334 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0781303 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0774509 |
| RPL35A | ribosomal protein L35a | -0.0758378 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0749058 |
| USP34 | ubiquitin specific peptidase 34 | -0.0740642 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0699141 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0649176 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0646184 |
| RBM39 | RNA binding motif protein 39 | -0.0645129 |
| CDH13 | cadherin 13 | -0.0617256 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0609286 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0597978 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.059328 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0583747 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0573825 |
| OSMR | oncostatin M receptor | -0.0554691 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0543451 |
| MTSS1 | metastasis suppressor 1 | -0.0526242 |
| VRK2 | vaccinia related kinase 2 | -0.0511371 |
| AHNAK | AHNAK nucleoprotein | -0.0508613 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0496616 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0483768 |
| EFNA5 | ephrin-A5 | -0.04764 |
| RPS19 | ribosomal protein S19 | -0.0468949 |
| UBC | ubiquitin C | -0.046338 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0463238 |
| NAV2 | neuron navigator 2 | -0.0449774 |
| ATG7 | autophagy related 7 | -0.0440982 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0437325 |
| FAM20C | family with sequence similarity 20, member C | -0.0434816 |
| PTK2 | protein tyrosine kinase 2 | -0.042661 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0424366 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0420882 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0418883 |
| NUMB | numb homolog (Drosophila) | -0.0417384 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0415798 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0411516 |
| RPL34 | ribosomal protein L34 | -0.0409472 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0407371 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.040627 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0390906 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0390065 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0379069 |
| ACTG1 | actin gamma 1 | -0.0373544 |
| DNER | delta/notch-like EGF repeat containing | -0.0373044 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.036962 |
| RPS21 | ribosomal protein S21 | -0.0369044 |
| FRMD4A | FERM domain containing 4A | -0.0365481 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0359887 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0358851 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0354356 |
| TMEM165 | transmembrane protein 165 | -0.0351087 |
| ZNF638 | zinc finger protein 638 | -0.0346967 |
| RPS6 | ribosomal protein S6 | -0.0340273 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0336393 |
| RPL23 | ribosomal protein L23 | -0.0335457 |
| RPL32 | ribosomal protein L32 | -0.0333698 |
| KYNU | kynureninase | -0.0332812 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0331779 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0327291 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0321309 |
| RPS11 | ribosomal protein S11 | -0.0319788 |
| RPS23 | ribosomal protein S23 | -0.031892 |
| CFDP1 | craniofacial development protein 1 | -0.0317038 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0316342 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0314477 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0313104 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0312127 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0308805 |
| DIAPH2 | diaphanous-related formin 2 | -0.030707 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0302703 |
| PYGL | phosphorylase, glycogen, liver | -0.0299868 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0299739 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0298514 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0296532 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0295813 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0289191 |
| TMEM263 | transmembrane protein 263 | -0.0287999 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0285163 |
| NAV3 | neuron navigator 3 | -0.0283135 |
| S100A10 | S100 calcium binding protein A10 | -0.028286 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0282229 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0282009 |
| ETV6 | ets variant 6 | -0.0280658 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0279761 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0278444 |
| NHSL1 | NHS-like 1 | -0.0275092 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0274606 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0273465 |
| CANX | calnexin | -0.0270271 |
