| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Trifluridine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.207285 |
| MT2A | metallothionein 2A | 0.164815 |
| VIM | vimentin | 0.145985 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.132122 |
| LDHA | lactate dehydrogenase A | 0.119123 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.106236 |
| S100A6 | S100 calcium binding protein A6 | 0.10158 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0907646 |
| PYGL | phosphorylase, glycogen, liver | 0.0801779 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0791993 |
| MCL1 | myeloid cell leukemia 1 | 0.0771132 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.070865 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0689153 |
| ANGPTL4 | angiopoietin-like 4 | 0.0660262 |
| RPS8 | ribosomal protein S8 | 0.0650531 |
| STC1 | stanniocalcin 1 | 0.0648919 |
| FMNL2 | formin-like 2 | 0.062193 |
| FAM107B | family with sequence similarity 107, member B | 0.0594538 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0584495 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0580405 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0528311 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0527344 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0513787 |
| TPI1 | triosephosphate isomerase 1 | 0.0506155 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0505176 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0502917 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.050053 |
| RPS3 | ribosomal protein S3 | 0.048978 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0469285 |
| FLNB | filamin B, beta | 0.0467721 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0464696 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0457181 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0456039 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0450317 |
| HLA-A | major histocompatibility complex, class I, A | 0.0442903 |
| WAC | WW domain containing adaptor with coiled-coil | 0.041695 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0409484 |
| SVIL | supervillin | 0.0392311 |
| RPS2 | ribosomal protein S2 | 0.0386163 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0373434 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0357936 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0353468 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0353185 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.034888 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0348454 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0336504 |
| TPM3 | tropomyosin 3 | 0.0334109 |
| CALR | calreticulin | 0.0333794 |
| SQSTM1 | sequestosome 1 | 0.0331875 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0325844 |
| MYOF | myoferlin | 0.0321367 |
| SFTPA2 | surfactant protein A2 | 0.0317752 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0316324 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0315448 |
| NDRG1 | N-myc downstream regulated 1 | 0.0313747 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0313463 |
| PKM | pyruvate kinase, muscle | 0.0311148 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0310727 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0308888 |
| MYADM | myeloid-associated differentiation marker | 0.0304699 |
| ANXA1 | annexin A1 | 0.0301483 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0299457 |
| FNBP1L | formin binding protein 1-like | 0.0276637 |
| MYO1E | myosin IE | 0.0275314 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.027488 |
| B2M | beta-2-microglobulin | 0.0274731 |
| JMJD1C | jumonji domain containing 1C | 0.0274705 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0271731 |
| PDE10A | phosphodiesterase 10A | 0.0268428 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0266947 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0266543 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0266526 |
| CDCP1 | CUB domain containing protein 1 | 0.0265826 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0263829 |
| HYOU1 | hypoxia up-regulated 1 | 0.026133 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0258517 |
| ENO1 | enolase 1, (alpha) | 0.0252118 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0248133 |
| NEBL | nebulette | 0.0245505 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0244668 |
| KIAA0319 | KIAA0319 | 0.0243223 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0242073 |
| IGF2 | insulin-like growth factor 2 | 0.0239722 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0239158 |
| SLMAP | sarcolemma associated protein | 0.023763 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0236311 |
| RPS12 | ribosomal protein S12 | 0.0232401 |
| JUN | jun proto-oncogene | 0.0231822 |
| RPS7 | ribosomal protein S7 | 0.0230196 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0229769 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0229373 |
| CAVIN1 | caveolae associated protein 1 | 0.0229324 |
| CCNY | cyclin Y | 0.0228728 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0226657 |
| FLNA | filamin A, alpha | 0.0221536 |
| EGR1 | early growth response 1 | 0.0215194 |
| SBF2 | SET binding factor 2 | 0.0212536 |
| KIF13A | kinesin family member 13A | 0.0211389 |
| HLA-B | major histocompatibility complex, class I, B | 0.0207302 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.020689 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.122035 |
| TMSB10 | thymosin beta 10 | -0.0957561 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0950441 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0937128 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0869758 |
| FGB | fibrinogen beta chain | -0.0730968 |
| CENPF | centromere protein F, 350/400kDa | -0.070229 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0662319 |
| GRAMD1B | GRAM domain containing 1B | -0.0644018 |
| RPS19 | ribosomal protein S19 | -0.0614411 |
| WDR43 | WD repeat domain 43 | -0.0589332 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0554689 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0546515 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0538382 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0534644 |
| MKI67 | marker of proliferation Ki-67 | -0.0527858 |
| RPS21 | ribosomal protein S21 | -0.0519422 |
| RPS29 | ribosomal protein S29 | -0.050676 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0483954 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.047856 |
| RPL35A | ribosomal protein L35a | -0.0451588 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0450087 |
| NRG1 | neuregulin 1 | -0.0427768 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0416379 |
| RPL36 | ribosomal protein L36 | -0.0403609 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0396744 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0394861 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0389208 |
| KLF6 | Kruppel-like factor 6 | -0.0386564 |
| RPL32 | ribosomal protein L32 | -0.0386381 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0368304 |
| RAB10 | RAB10, member RAS oncogene family | -0.036223 |
| ANLN | anillin, actin binding protein | -0.0350002 |
| DEK | DEK proto-oncogene | -0.0348936 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343198 |
| RPL23 | ribosomal protein L23 | -0.0338897 |
| TPX2 | TPX2, microtubule-associated | -0.0335184 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0332091 |
| WTAP | Wilms tumor 1 associated protein | -0.0329507 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0325338 |
| RTN4 | reticulon 4 | -0.0321507 |
| RHEB | Ras homolog enriched in brain | -0.0318581 |
| AHNAK | AHNAK nucleoprotein | -0.0318345 |
| CENPE | centromere protein E, 312kDa | -0.0308181 |
| ACTG1 | actin gamma 1 | -0.0307861 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0304517 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.030408 |
| SP3 | Sp3 transcription factor | -0.0302797 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0300851 |
| RPS15 | ribosomal protein S15 | -0.0299407 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0299024 |
| RPS5 | ribosomal protein S5 | -0.0298557 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0295883 |
| FGG | fibrinogen gamma chain | -0.0292123 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0289592 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0288619 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0285024 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0278856 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0277803 |
| RPS16 | ribosomal protein S16 | -0.027557 |
| HMGB1 | high mobility group box 1 | -0.0274807 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0273163 |
| RPL34 | ribosomal protein L34 | -0.0268528 |
| YBX1 | Y box binding protein 1 | -0.0268289 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0267719 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0267062 |
| COG5 | component of oligomeric golgi complex 5 | -0.0264348 |
| RPS20 | ribosomal protein S20 | -0.0264258 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0264086 |
| RRM2 | ribonucleotide reductase M2 | -0.0263756 |
| ECT2 | epithelial cell transforming 2 | -0.0263661 |
| MATR3 | matrin 3 | -0.0261518 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0257674 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0256073 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0254674 |
| BICC1 | BicC family RNA binding protein 1 | -0.0254543 |
| FAM168A | family with sequence similarity 168, member A | -0.025412 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0253541 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0250739 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0248167 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0247895 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0247692 |
| RASAL2 | RAS protein activator like 2 | -0.0245063 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0244187 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0241926 |
| GLG1 | golgi glycoprotein 1 | -0.0241259 |
| FGA | fibrinogen alpha chain | -0.0240448 |
| DIAPH3 | diaphanous-related formin 3 | -0.0239682 |
| HBS1L | HBS1-like translational GTPase | -0.0239288 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0239228 |
| OLA1 | Obg-like ATPase 1 | -0.0238319 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0237495 |
| TFG | TRK-fused gene | -0.0237357 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0236814 |
| SGO2 | shugoshin 2 | -0.0236469 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -0.0235602 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.023557 |
| TMPO | thymopoietin | -0.0235208 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0233151 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0232478 |
