| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.127786 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.120914 |
| PCDH9 | protocadherin 9 | 0.087819 |
| RPS12 | ribosomal protein S12 | 0.0844011 |
| PTMA | prothymosin, alpha | 0.0806128 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0707571 |
| RPS16 | ribosomal protein S16 | 0.0621344 |
| RPS8 | ribosomal protein S8 | 0.0620057 |
| PEG10 | paternally expressed 10 | 0.0582845 |
| TMSB10 | thymosin beta 10 | 0.054605 |
| RPS3 | ribosomal protein S3 | 0.0525164 |
| RPL37A | ribosomal protein L37a | 0.0517479 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0492861 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.048461 |
| RAI1 | retinoic acid induced 1 | 0.0478787 |
| B2M | beta-2-microglobulin | 0.0469274 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0427363 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0426387 |
| RPS2 | ribosomal protein S2 | 0.042418 |
| RPL9 | ribosomal protein L9 | 0.0420395 |
| NTM | neurotrimin | 0.042034 |
| LDHA | lactate dehydrogenase A | 0.0418327 |
| PHIP | pleckstrin homology domain interacting protein | 0.041661 |
| ITGAV | integrin, alpha V | 0.0415005 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0411951 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0391672 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0384513 |
| TMEM87A | transmembrane protein 87A | 0.0379184 |
| USP34 | ubiquitin specific peptidase 34 | 0.037869 |
| SRP54 | signal recognition particle 54kDa | 0.0374785 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0370635 |
| RPS17 | ribosomal protein S17 | 0.036713 |
| CALR | calreticulin | 0.0365325 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0361867 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0350665 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0350011 |
| SON | SON DNA binding protein | 0.0344958 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0342183 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0341934 |
| NOP58 | NOP58 ribonucleoprotein | 0.0337583 |
| HDAC9 | histone deacetylase 9 | 0.0336115 |
| FTL | ferritin, light polypeptide | 0.033569 |
| RPS13 | ribosomal protein S13 | 0.0335499 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0334446 |
| FST | follistatin | 0.0321424 |
| SNX6 | sorting nexin 6 | 0.0321091 |
| UBXN4 | UBX domain protein 4 | 0.0318773 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0318384 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0317784 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0310471 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0309087 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0301316 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0296851 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0296712 |
| RPS25 | ribosomal protein S25 | 0.0296171 |
| RPL12 | ribosomal protein L12 | 0.029433 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0294214 |
| ASPH | aspartate beta-hydroxylase | 0.0293832 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0287589 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0286824 |
| MYO9A | myosin IXA | 0.0285832 |
| YAF2 | YY1 associated factor 2 | 0.0283738 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0280724 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.027949 |
| TOP1 | topoisomerase (DNA) I | 0.0278994 |
| RPL23 | ribosomal protein L23 | 0.0275161 |
| TUBA1B | tubulin, alpha 1b | 0.0273627 |
| RACK1 | receptor for activated C kinase 1 | 0.0272689 |
| APOE | apolipoprotein E | 0.0268756 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.026617 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0266136 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.026536 |
| SNX3 | sorting nexin 3 | 0.0263962 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.026247 |
| RPL5 | ribosomal protein L5 | 0.0261904 |
| URI1 | URI1, prefoldin-like chaperone | 0.0261901 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0260121 |
| TP53 | tumor protein p53 | 0.0260119 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0259457 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0258819 |
| POTEF | POTE ankyrin domain family, member F | 0.025829 |
| S100A9 | S100 calcium binding protein A9 | 0.0257361 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0254465 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0254023 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0253902 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0251079 |
| SARS1 | seryl-tRNA synthetase 1 | 0.025103 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0249667 |
| RPL7A | ribosomal protein L7a | 0.0245666 |
| FN1 | fibronectin 1 | 0.0244112 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.024256 |
| ENO1 | enolase 1, (alpha) | 0.0242072 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0241988 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.0241132 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.0240775 |
| RPL31 | ribosomal protein L31 | 0.0240443 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0239854 |
| PDE10A | phosphodiesterase 10A | 0.0238401 |
| CBX3 | chromobox homolog 3 | 0.023835 |
| SETD5 | SET domain containing 5 | 0.023809 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | -0.176053 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.148938 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.129533 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105128 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.101468 |
| TENM3 | teneurin transmembrane protein 3 | -0.100398 |
| ACTG1 | actin gamma 1 | -0.0884368 |
| COL3A1 | collagen, type III, alpha 1 | -0.0834811 |
| DST | dystonin | -0.0758744 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0752653 |
| H1-0 | H1.0 linker histone | -0.0707423 |
| AHNAK | AHNAK nucleoprotein | -0.0705175 |
| THBS1 | thrombospondin 1 | -0.0696991 |
| MKI67 | marker of proliferation Ki-67 | -0.0634295 |
| PDGFC | platelet derived growth factor C | -0.0610865 |
| ZNF292 | zinc finger protein 292 | -0.0589887 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0565716 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0553802 |
| EMP1 | epithelial membrane protein 1 | -0.0546482 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.051322 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0505454 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0474252 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0470467 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0469626 |
| MPG | N-methylpurine-DNA glycosylase | -0.0460581 |
| APP | amyloid beta (A4) precursor protein | -0.0457686 |
| CENPE | centromere protein E, 312kDa | -0.0444182 |
| ZNF217 | zinc finger protein 217 | -0.04416 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0429213 |
| FOXP2 | forkhead box P2 | -0.0425303 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0423284 |
| SGO2 | shugoshin 2 | -0.0421125 |
| TMSB4X | thymosin beta 4, X-linked | -0.0416401 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0407843 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0405369 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0402904 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0399008 |
| RBM39 | RNA binding motif protein 39 | -0.0392698 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0389678 |
| NF1 | neurofibromin 1 | -0.0385808 |
| VCL | vinculin | -0.0384732 |
| CENPF | centromere protein F, 350/400kDa | -0.0382169 |
| ENAH | enabled homolog (Drosophila) | -0.0376373 |
| ACTN4 | actinin, alpha 4 | -0.0375572 |
| KIF4A | kinesin family member 4A | -0.0369278 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0365655 |
| MEF2C | myocyte enhancer factor 2C | -0.0360347 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0358062 |
| STAG2 | stromal antigen 2 | -0.0354688 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0347741 |
| TEX11 | testis expressed 11 | -0.0346909 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0344649 |
| FIGN | fidgetin | -0.0343452 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0340222 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0334422 |
| TPX2 | TPX2, microtubule-associated | -0.033203 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | -0.0331734 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0330416 |
| CLIC4 | chloride intracellular channel 4 | -0.0330314 |
| ZNF608 | zinc finger protein 608 | -0.0324285 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -0.0323432 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0318851 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0314259 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0311879 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0311088 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | -0.0310021 |
| CALU | calumenin | -0.0309319 |
| ECT2 | epithelial cell transforming 2 | -0.0308604 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0308603 |
| RHEB | Ras homolog enriched in brain | -0.0305709 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0305039 |
| NFIA | nuclear factor I/A | -0.0296188 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0295047 |
| PRELID2 | PRELI domain containing 2 | -0.0291567 |
| GPC3 | glypican 3 | -0.0291495 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0290072 |
| MEIS2 | Meis homeobox 2 | -0.0290019 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0289821 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0285348 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0284684 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0283932 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0282543 |
| RAB31 | RAB31, member RAS oncogene family | -0.0282216 |
| SHROOM3 | shroom family member 3 | -0.0280967 |
| RYBP | RING1 and YY1 binding protein | -0.027966 |
| PRR11 | proline rich 11 | -0.0278905 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0277341 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.027728 |
| DEK | DEK proto-oncogene | -0.027673 |
| CEP192 | centrosomal protein 192kDa | -0.0276212 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.027457 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0272832 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0271331 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0269253 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0266095 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262111 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.025954 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0256801 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0254924 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0254608 |
