| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.320289 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.149019 |
| VCL | vinculin | 0.120563 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0963215 |
| RPS8 | ribosomal protein S8 | 0.0885872 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.087059 |
| ENO1 | enolase 1, (alpha) | 0.0858166 |
| RPS3 | ribosomal protein S3 | 0.0841132 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0828459 |
| MKI67 | marker of proliferation Ki-67 | 0.0804343 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.075012 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0702764 |
| RPL26 | ribosomal protein L26 | 0.0668064 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0654145 |
| RPS12 | ribosomal protein S12 | 0.0637387 |
| TMSB4X | thymosin beta 4, X-linked | 0.0624478 |
| TJP1 | tight junction protein 1 | 0.0607366 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0602143 |
| RPLP0 | ribosomal protein, large, P0 | 0.0574514 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0558752 |
| LDHA | lactate dehydrogenase A | 0.0551174 |
| PKM | pyruvate kinase, muscle | 0.0528825 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0519618 |
| TPI1 | triosephosphate isomerase 1 | 0.0518447 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0517742 |
| RACK1 | receptor for activated C kinase 1 | 0.0515798 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0514631 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0496617 |
| GNAS | GNAS complex locus | 0.0495892 |
| RPL31 | ribosomal protein L31 | 0.0490612 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.0488954 |
| CENPF | centromere protein F, 350/400kDa | 0.0486672 |
| BMP10 | bone morphogenetic protein 10 | 0.0484341 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0483126 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0480808 |
| RPS2 | ribosomal protein S2 | 0.0479513 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0473446 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0469888 |
| ANXA1 | annexin A1 | 0.0465894 |
| DUSP6 | dual specificity phosphatase 6 | 0.0457847 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0444093 |
| PGK1 | phosphoglycerate kinase 1 | 0.0441135 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0439045 |
| RPS6 | ribosomal protein S6 | 0.043834 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0437458 |
| RPL9 | ribosomal protein L9 | 0.042367 |
| RPS13 | ribosomal protein S13 | 0.0416079 |
| S100A4 | S100 calcium binding protein A4 | 0.0408572 |
| DIAPH3 | diaphanous-related formin 3 | 0.0408566 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0407467 |
| KIF5B | kinesin family member 5B | 0.040618 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0404607 |
| TPM4 | tropomyosin 4 | 0.0398327 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0385729 |
| SET | SET nuclear proto-oncogene | 0.0384217 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0377043 |
| MYO5C | myosin VC | 0.0371412 |
| RPL37A | ribosomal protein L37a | 0.0367259 |
| MATR3 | matrin 3 | 0.0362427 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0360172 |
| FOXP1 | forkhead box P1 | 0.0359391 |
| RPL36A | ribosomal protein L36a | 0.0357369 |
| TPX2 | TPX2, microtubule-associated | 0.0356985 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0356157 |
| RPS27A | ribosomal protein S27a | 0.0354733 |
| TUBA1B | tubulin, alpha 1b | 0.0347605 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0345847 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0345429 |
| GLI3 | GLI family zinc finger 3 | 0.0344819 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0340136 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0339399 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.033732 |
| ANLN | anillin, actin binding protein | 0.0329896 |
| RPLP2 | ribosomal protein, large, P2 | 0.0328343 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0326645 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0321241 |
| RRM2 | ribonucleotide reductase M2 | 0.0318654 |
| RPL7A | ribosomal protein L7a | 0.0317238 |
| HDAC9 | histone deacetylase 9 | 0.0316075 |
| SMC3 | structural maintenance of chromosomes 3 | 0.03104 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0309891 |
| TUBB | tubulin, beta class I | 0.0309481 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0305827 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0305386 |
| RPL7 | ribosomal protein L7 | 0.0305196 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0303701 |
| RPS17 | ribosomal protein S17 | 0.0302087 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0300334 |
| HMGB2 | high mobility group box 2 | 0.0299363 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0298601 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0298586 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0295791 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0291811 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0288012 |
| MACROD2 | MACRO domain containing 2 | 0.0287275 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0286004 |
| LDHB | lactate dehydrogenase B | 0.0285215 |
| NOP56 | NOP56 ribonucleoprotein | 0.0279625 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0278905 |
| RPL18 | ribosomal protein L18 | 0.0276623 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.160277 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0529386 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0454293 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0424853 |
| RTN4 | reticulon 4 | -0.0403014 |
| RPL35A | ribosomal protein L35a | -0.0399509 |
| FLNB | filamin B, beta | -0.0366816 |
| ANK2 | ankyrin 2, neuronal | -0.0365734 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0322283 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0317251 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0312091 |
| NBAS | neuroblastoma amplified sequence | -0.0308944 |
| CCNL1 | cyclin L1 | -0.0267531 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0264281 |
| JMJD1C | jumonji domain containing 1C | -0.02575 |
| RPS23 | ribosomal protein S23 | -0.0254039 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0253441 |
| TBC1D22A | TBC1 domain family, member 22A | -0.025325 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0251549 |
| ETNK1 | ethanolamine kinase 1 | -0.0248551 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0246436 |
| ZNF292 | zinc finger protein 292 | -0.0239557 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0235313 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0231227 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0227933 |
| BRD2 | bromodomain containing 2 | -0.022676 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0220383 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0210655 |
| ARRDC3 | arrestin domain containing 3 | -0.021043 |
| COG5 | component of oligomeric golgi complex 5 | -0.0206554 |
| SBF2 | SET binding factor 2 | -0.0206422 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.020432 |
| PTEN | phosphatase and tensin homolog | -0.0203363 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0202169 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0200864 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0199538 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0195981 |
| TMEM41B | transmembrane protein 41B | -0.0193925 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0191995 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0184954 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.018492 |
| ATXN1 | ataxin 1 | -0.018279 |
| ARF4 | ADP-ribosylation factor 4 | -0.0182155 |
| POTEF | POTE ankyrin domain family, member F | -0.0181664 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0180103 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0178364 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.017761 |
| PCBP2 | poly(rC) binding protein 2 | -0.0176431 |
| DIAPH2 | diaphanous-related formin 2 | -0.0175958 |
| RPL3 | ribosomal protein L3 | -0.0175407 |
| UBC | ubiquitin C | -0.0175231 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0175173 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0173267 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0173161 |
| TPD52 | tumor protein D52 | -0.0169065 |
| TAPBP | TAP binding protein (tapasin) | -0.0168812 |
| COG6 | component of oligomeric golgi complex 6 | -0.0166641 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0165762 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | -0.0165319 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0164994 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0163971 |
| RUNX1 | runt-related transcription factor 1 | -0.0162922 |
| ATOSA | atos homolog A | -0.0162602 |
| OLA1 | Obg-like ATPase 1 | -0.0160468 |
| ZNF638 | zinc finger protein 638 | -0.0159963 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0158557 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0157767 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0157647 |
| INTS6 | integrator complex subunit 6 | -0.0156902 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.0156715 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.015665 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0156536 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0155669 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0155507 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0154666 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -0.0154252 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0153105 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0152993 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.015283 |
| UBP1 | upstream binding protein 1 (LBP-1a) | -0.0152789 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0152587 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0151397 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.015123 |
| CCDC93 | coiled-coil domain containing 93 | -0.0149663 |
| CABIN1 | calcineurin binding protein 1 | -0.0148755 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0148713 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0148669 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0148612 |
| DENND4A | DENN/MADD domain containing 4A | -0.0148542 |
| SEC24D | SEC24 family member D | -0.0147421 |
| WDR26 | WD repeat domain 26 | -0.0146946 |
| RHBDD1 | rhomboid domain containing 1 | -0.0146365 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0146174 |
| GOLGA4 | golgin A4 | -0.0145876 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0145704 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0145588 |
| INSIG1 | insulin induced gene 1 | -0.0145267 |
| TXNRD1 | thioredoxin reductase 1 | -0.0144805 |
| KIAA1328 | KIAA1328 | -0.0144368 |
| TDRD3 | tudor domain containing 3 | -0.0144194 |
