| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.223503 |
| VIM | vimentin | 0.154123 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.130055 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.125015 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.107954 |
| B2M | beta-2-microglobulin | 0.102192 |
| ENO1 | enolase 1, (alpha) | 0.0991494 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0951368 |
| NRXN3 | neurexin 3 | 0.0894331 |
| STC1 | stanniocalcin 1 | 0.0890991 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0877587 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0853566 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0752827 |
| POTEF | POTE ankyrin domain family, member F | 0.0669057 |
| PRSS23 | protease, serine, 23 | 0.0657322 |
| IL6 | interleukin 6 | 0.0625261 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0623014 |
| FTL | ferritin, light polypeptide | 0.0572373 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0568679 |
| CDH13 | cadherin 13 | 0.0537463 |
| VEGFA | vascular endothelial growth factor A | 0.0533122 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0526734 |
| LDHA | lactate dehydrogenase A | 0.0502122 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0501458 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.049811 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0486127 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0482715 |
| PRKCA | protein kinase C, alpha | 0.0462831 |
| HLA-B | major histocompatibility complex, class I, B | 0.0455528 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.045353 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.044223 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.04392 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0420363 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0398901 |
| TMSB10 | thymosin beta 10 | 0.0396226 |
| CALU | calumenin | 0.0392087 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.039089 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0383846 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0379785 |
| KYNU | kynureninase | 0.0366507 |
| RAD51B | RAD51 paralog B | 0.0365659 |
| EXOC6B | exocyst complex component 6B | 0.0365498 |
| PRELID2 | PRELI domain containing 2 | 0.0362969 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.035988 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0354992 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0351739 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0346154 |
| HLA-A | major histocompatibility complex, class I, A | 0.0342918 |
| HMGA2 | high mobility group AT-hook 2 | 0.0333723 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0330911 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0330844 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0329255 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0326911 |
| MED13L | mediator complex subunit 13-like | 0.031911 |
| FLNA | filamin A, alpha | 0.0316381 |
| GLIS3 | GLIS family zinc finger 3 | 0.0312933 |
| ACTN1 | actinin, alpha 1 | 0.0311271 |
| MORF4L2 | mortality factor 4 like 2 | 0.0310477 |
| EGR1 | early growth response 1 | 0.0309147 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0306424 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0302316 |
| MAP1B | microtubule-associated protein 1B | 0.0301733 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0299429 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0294505 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0285797 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0284511 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0283416 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0280204 |
| RPL37A | ribosomal protein L37a | 0.0277724 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0277089 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0276747 |
| CCNI | cyclin I | 0.0276705 |
| COL6A1 | collagen, type VI, alpha 1 | 0.027649 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0275228 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.027312 |
| CENPF | centromere protein F, 350/400kDa | 0.0272884 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0272689 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0271766 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0269948 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0268225 |
| PRR11 | proline rich 11 | 0.0265749 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0263646 |
| RPS8 | ribosomal protein S8 | 0.0261742 |
| MKI67 | marker of proliferation Ki-67 | 0.026009 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.02579 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0256853 |
| IKBIP | IKBKB interacting protein | 0.0256273 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0255218 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0254357 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0252265 |
| PTN | pleiotrophin | 0.0249785 |
| FOSL1 | FOS-like antigen 1 | 0.0249546 |
| TMEM165 | transmembrane protein 165 | 0.0241044 |
| RACK1 | receptor for activated C kinase 1 | 0.0240424 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0239384 |
| NAV1 | neuron navigator 1 | 0.0238044 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0236907 |
| TBCA | tubulin folding cofactor A | 0.0235656 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0233343 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.023299 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.0937605 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0733023 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0646528 |
| CADM1 | cell adhesion molecule 1 | -0.051811 |
| RBM39 | RNA binding motif protein 39 | -0.0513745 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.048374 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0465332 |
| FN1 | fibronectin 1 | -0.045003 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0443341 |
| NDRG1 | N-myc downstream regulated 1 | -0.0439241 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0407582 |
| PTMA | prothymosin, alpha | -0.0396509 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0383774 |
| MATR3 | matrin 3 | -0.0378675 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.034377 |
| TMEM263 | transmembrane protein 263 | -0.0327395 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0327343 |
| SUCO | SUN domain containing ossification factor | -0.0316569 |
| RRBP1 | ribosome binding protein 1 | -0.0314216 |
| TPR | translocated promoter region, nuclear basket protein | -0.0299354 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0295214 |
| OGA | O-GlcNAcase | -0.0293929 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0293353 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0286957 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0274887 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.027441 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0271289 |
| UBE3C | ubiquitin protein ligase E3C | -0.0270139 |
| ANXA5 | annexin A5 | -0.0268634 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0266866 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0266212 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0262902 |
| SRPK2 | SRSF protein kinase 2 | -0.026077 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.025857 |
| SERF2 | small EDRK-rich factor 2 | -0.0253934 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0253794 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0252837 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0252825 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0250811 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0247883 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0247832 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0246033 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.0241195 |
| ARRDC3 | arrestin domain containing 3 | -0.0240061 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0238882 |
| ZHX3 | zinc fingers and homeoboxes 3 | -0.0238693 |
| RPLP1 | ribosomal protein, large, P1 | -0.0238627 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0237869 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0235452 |
| RPL36A | ribosomal protein L36a | -0.023336 |
| KIF13A | kinesin family member 13A | -0.0232295 |
| GPC6 | glypican 6 | -0.0231483 |
| HIP1 | huntingtin interacting protein 1 | -0.0231208 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0230329 |
| COL5A2 | collagen, type V, alpha 2 | -0.022672 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0225093 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0223936 |
| MAP4 | microtubule-associated protein 4 | -0.0222886 |
| SDC4 | syndecan 4 | -0.0219781 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0219742 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0217575 |
| AOPEP | aminopeptidase O (putative) | -0.0216246 |
| ERBIN | erbb2 interacting protein | -0.0216226 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0216075 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0216013 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0213143 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0211219 |
| OSMR | oncostatin M receptor | -0.0209368 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.020923 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.020835 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0207855 |
| XPO1 | exportin 1 | -0.020776 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0204134 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0203491 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0202277 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0199677 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0199394 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0199171 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0198484 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0198246 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0197479 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0196434 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0195897 |
| MYOF | myoferlin | -0.0195382 |
| FNBP4 | formin binding protein 4 | -0.0194191 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0193407 |
| FOXJ3 | forkhead box J3 | -0.0193391 |
| RTN4 | reticulon 4 | -0.0192735 |
| CLINT1 | clathrin interactor 1 | -0.0192023 |
| ITM2B | integral membrane protein 2B | -0.0190329 |
| RBM33 | RNA binding motif protein 33 | -0.0189777 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0189491 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0189415 |
| ZNF292 | zinc finger protein 292 | -0.0189329 |
| SNX13 | sorting nexin 13 | -0.0189083 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0187937 |
| TNNC1 | troponin C type 1 (slow) | -0.0187532 |
| RPL3 | ribosomal protein L3 | -0.0186986 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0186674 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0186103 |
