| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.135325 |
| CD44 | CD44 molecule (Indian blood group) | 0.0939787 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0914433 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0798277 |
| SMAD3 | SMAD family member 3 | 0.0616553 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0600904 |
| TXNRD1 | thioredoxin reductase 1 | 0.0596625 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0571408 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0570759 |
| YBX3 | Y box binding protein 3 | 0.056651 |
| RTN4 | reticulon 4 | 0.0561334 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.054411 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0540931 |
| ITSN2 | intersectin 2 | 0.0520062 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0518458 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0512821 |
| SQSTM1 | sequestosome 1 | 0.0504593 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0497372 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0494306 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.047468 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0467458 |
| RIGI | RNA sensor RIG-I | 0.0463881 |
| PKM | pyruvate kinase, muscle | 0.04543 |
| ANGPTL4 | angiopoietin-like 4 | 0.0444685 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0435681 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0412053 |
| YAP1 | Yes-associated protein 1 | 0.0405701 |
| MT2A | metallothionein 2A | 0.0405153 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0401696 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.039912 |
| VMP1 | vacuole membrane protein 1 | 0.0383874 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.038286 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0381869 |
| SVIL | supervillin | 0.0380041 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0375271 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0374806 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0374212 |
| FMNL2 | formin-like 2 | 0.0370685 |
| MATR3 | matrin 3 | 0.0364789 |
| RPS12 | ribosomal protein S12 | 0.0363999 |
| SEPTIN7 | septin 7 | 0.0358532 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0343142 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0340596 |
| ANO6 | anoctamin 6 | 0.0338923 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.0335724 |
| NAV3 | neuron navigator 3 | 0.0329576 |
| DIAPH1 | diaphanous-related formin 1 | 0.0325942 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.032427 |
| JMJD1C | jumonji domain containing 1C | 0.0318528 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0318506 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0316143 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0309938 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0309843 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0309535 |
| HDAC9 | histone deacetylase 9 | 0.0308167 |
| FOSL1 | FOS-like antigen 1 | 0.0303772 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0303103 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0297566 |
| MSN | moesin | 0.0294465 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0291685 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0291583 |
| H3-3B | H3.3 histone B | 0.0289932 |
| HDAC8 | histone deacetylase 8 | 0.0289185 |
| SLMAP | sarcolemma associated protein | 0.0288924 |
| ANXA2 | annexin A2 | 0.0288705 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0286856 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0286657 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0283687 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0282849 |
| DGKH | diacylglycerol kinase, eta | 0.0282777 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0280936 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.027993 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0277859 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0275244 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0274114 |
| EFNA5 | ephrin-A5 | 0.0273516 |
| PLCB4 | phospholipase C, beta 4 | 0.0271554 |
| CENPE | centromere protein E, 312kDa | 0.0271285 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.027071 |
| FAM3C | family with sequence similarity 3, member C | 0.0265794 |
| DENND4A | DENN/MADD domain containing 4A | 0.0265035 |
| SET | SET nuclear proto-oncogene | 0.0263956 |
| NAV2 | neuron navigator 2 | 0.0263798 |
| PRSS23 | protease, serine, 23 | 0.0261487 |
| TMEM87A | transmembrane protein 87A | 0.0261355 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0261007 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0259939 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0258611 |
| STK24 | serine/threonine kinase 24 | 0.0254437 |
| ZNF292 | zinc finger protein 292 | 0.0253643 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0253627 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0252214 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0252191 |
| STK38L | serine/threonine kinase 38 like | 0.0251326 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0250045 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0249589 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0248599 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0247479 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0246053 |
| MSH3 | mutS homolog 3 | 0.0245457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.359457 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.114104 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100025 |
| AHNAK | AHNAK nucleoprotein | -0.0939515 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0787679 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.068296 |
| PTMA | prothymosin, alpha | -0.0680239 |
| INTS6 | integrator complex subunit 6 | -0.0553693 |
| HMGA2 | high mobility group AT-hook 2 | -0.0552914 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0526471 |
| ATM | ATM serine/threonine kinase | -0.05043 |
| CANX | calnexin | -0.049876 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0475273 |
| PRELID2 | PRELI domain containing 2 | -0.0465574 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0465478 |
| DENND1A | DENN/MADD domain containing 1A | -0.0459968 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0441803 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0438008 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0430632 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0424271 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0412864 |
| CALU | calumenin | -0.0407796 |
| RNF213 | ring finger protein 213 | -0.0391247 |
| RPL35A | ribosomal protein L35a | -0.0387649 |
| ASPH | aspartate beta-hydroxylase | -0.0385341 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0359708 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0345799 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.033551 |
| GOLGA3 | golgin A3 | -0.0333823 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0332902 |
| PCNX4 | pecanex 4 | -0.0332737 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0331512 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0329115 |
| NUP98 | nucleoporin 98kDa | -0.0329007 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0328265 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0324571 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.032395 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0318903 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.031513 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0314686 |
| SNX14 | sorting nexin 14 | -0.031372 |
| PRR16 | proline rich 16 | -0.0312929 |
| GNAS | GNAS complex locus | -0.0311018 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0306793 |
| FLNB | filamin B, beta | -0.0305717 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0305085 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0303816 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0302317 |
| AEBP2 | AE binding protein 2 | -0.0299977 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0298201 |
| FMN1 | formin 1 | -0.0295514 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0291637 |
| OSMR | oncostatin M receptor | -0.0290721 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.028806 |
| JAZF1 | JAZF zinc finger 1 | -0.0286036 |
| IER3 | immediate early response 3 | -0.0285183 |
| DEK | DEK proto-oncogene | -0.0284219 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0284073 |
| RPL32 | ribosomal protein L32 | -0.0280955 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0279782 |
| ARF1 | ADP-ribosylation factor 1 | -0.0277464 |
| GOLGB1 | golgin B1 | -0.0277413 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0276907 |
| UBC | ubiquitin C | -0.0275284 |
| ACTG1 | actin gamma 1 | -0.0274999 |
| RPS15 | ribosomal protein S15 | -0.0273916 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0273622 |
| TAOK1 | TAO kinase 1 | -0.0273264 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0269496 |
| PRKCA | protein kinase C, alpha | -0.026808 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0266591 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0265996 |
| ATG7 | autophagy related 7 | -0.0265744 |
| CTTN | cortactin | -0.0259321 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0258361 |
| CCDC138 | coiled-coil domain containing 138 | -0.0257261 |
| RIN2 | Ras and Rab interactor 2 | -0.025607 |
| CLINT1 | clathrin interactor 1 | -0.0254238 |
| GLRX | glutaredoxin (thioltransferase) | -0.0252271 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0251462 |
| SCFD1 | sec1 family domain containing 1 | -0.0251038 |
| RPS21 | ribosomal protein S21 | -0.0251035 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0250079 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0250069 |
| NDRG1 | N-myc downstream regulated 1 | -0.02499 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0246759 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0245445 |
| CCNH | cyclin H | -0.0245314 |
| PYGL | phosphorylase, glycogen, liver | -0.0244736 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0244304 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0240767 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | -0.0237677 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0237332 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0235213 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 | -0.0234086 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0233686 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0233637 |
| USP53 | ubiquitin specific peptidase 53 | -0.023282 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0232387 |
| ATXN1 | ataxin 1 | -0.0230103 |
