| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Trifluridine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Trifluridine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.159883 |
| ASPH | aspartate beta-hydroxylase | 0.153944 |
| MT2A | metallothionein 2A | 0.138163 |
| VIM | vimentin | 0.103441 |
| FTL | ferritin, light polypeptide | 0.0945223 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0906477 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0880857 |
| RPS12 | ribosomal protein S12 | 0.0868912 |
| B2M | beta-2-microglobulin | 0.0739111 |
| ENO1 | enolase 1, (alpha) | 0.0702621 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0646238 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0631527 |
| EREG | epiregulin | 0.0595459 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0581589 |
| TOP1 | topoisomerase (DNA) I | 0.0580197 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0576253 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0575158 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0548113 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0533142 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0526995 |
| RPL26 | ribosomal protein L26 | 0.0520279 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.051204 |
| YBX3 | Y box binding protein 3 | 0.0493429 |
| AREG | amphiregulin | 0.0491926 |
| RPS3 | ribosomal protein S3 | 0.048998 |
| RPL9 | ribosomal protein L9 | 0.048411 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0481847 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0480898 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0449845 |
| NTN4 | netrin 4 | 0.0446249 |
| SVIL | supervillin | 0.0436655 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0434813 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0430893 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0428804 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0425624 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.042539 |
| OSMR | oncostatin M receptor | 0.04249 |
| DUSP6 | dual specificity phosphatase 6 | 0.0418277 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0417987 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.041699 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0413809 |
| RACK1 | receptor for activated C kinase 1 | 0.040121 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0401167 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0398561 |
| RPL37A | ribosomal protein L37a | 0.0387689 |
| AHR | aryl hydrocarbon receptor | 0.0384444 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0382526 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0380322 |
| RPL12 | ribosomal protein L12 | 0.0373824 |
| TPM3 | tropomyosin 3 | 0.0359597 |
| FOXP1 | forkhead box P1 | 0.0358678 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.035456 |
| CD44 | CD44 molecule (Indian blood group) | 0.0354397 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0354241 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0349368 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0345927 |
| SMAD3 | SMAD family member 3 | 0.0341493 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0338161 |
| SON | SON DNA binding protein | 0.0329183 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0324456 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0322853 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0322586 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0320688 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.031916 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0317657 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0315962 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0313845 |
| RPS8 | ribosomal protein S8 | 0.0308454 |
| SLTM | SAFB-like, transcription modulator | 0.0308434 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.030837 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0308088 |
| PELO | pelota homolog (Drosophila) | 0.0304289 |
| RPL7 | ribosomal protein L7 | 0.0302701 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0302419 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0302394 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0299768 |
| RNF213 | ring finger protein 213 | 0.0297544 |
| TXNRD1 | thioredoxin reductase 1 | 0.029583 |
| VCAN | versican | 0.0295492 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0292785 |
| CAB39 | calcium binding protein 39 | 0.0289409 |
| FHL2 | four and a half LIM domains 2 | 0.0288203 |
| TPI1 | triosephosphate isomerase 1 | 0.0286982 |
| LMNA | lamin A/C | 0.0280176 |
| LDHA | lactate dehydrogenase A | 0.0279823 |
| EGFR | epidermal growth factor receptor | 0.0277642 |
| TNNC1 | troponin C type 1 (slow) | 0.0276303 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.0276256 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0275993 |
| MAP1B | microtubule-associated protein 1B | 0.0275789 |
| RPL37 | ribosomal protein L37 | 0.0274054 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0273025 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0270296 |
| RPLP0 | ribosomal protein, large, P0 | 0.0270047 |
| ETV1 | ets variant 1 | 0.0269963 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0269829 |
| SERINC1 | serine incorporator 1 | 0.0267822 |
| DST | dystonin | 0.0267484 |
| GLIS3 | GLIS family zinc finger 3 | 0.0266398 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0264207 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.209386 |
| NRG1 | neuregulin 1 | -0.182059 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.147524 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.147247 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.110385 |
| FN1 | fibronectin 1 | -0.0749747 |
| VCL | vinculin | -0.0719846 |
| TMSB4X | thymosin beta 4, X-linked | -0.0693091 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0627752 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0608473 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0595569 |
| HLA-B | major histocompatibility complex, class I, B | -0.055271 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0551399 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0537734 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0502729 |
| ACTG1 | actin gamma 1 | -0.0488453 |
| CANX | calnexin | -0.0477134 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0474858 |
| VEGFA | vascular endothelial growth factor A | -0.0470527 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0455086 |
| AEBP2 | AE binding protein 2 | -0.0436274 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0433265 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0427318 |
| POTEF | POTE ankyrin domain family, member F | -0.0426077 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0398477 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.039498 |
| CADM1 | cell adhesion molecule 1 | -0.0392381 |
| ARF4 | ADP-ribosylation factor 4 | -0.0390621 |
| RPL35A | ribosomal protein L35a | -0.038823 |
| PTMA | prothymosin, alpha | -0.0385909 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0385642 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0383183 |
| COPA | coatomer protein complex, subunit alpha | -0.0379033 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0378889 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0374885 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0353911 |
| TMEM263 | transmembrane protein 263 | -0.0349427 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0348373 |
| SQSTM1 | sequestosome 1 | -0.0343999 |
| STC2 | stanniocalcin 2 | -0.0343087 |
| TMSB10 | thymosin beta 10 | -0.0340875 |
| SPAG9 | sperm associated antigen 9 | -0.0335767 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0332231 |
| NDRG1 | N-myc downstream regulated 1 | -0.0325163 |
| HMGB3 | high mobility group box 3 | -0.0322148 |
| RAI14 | retinoic acid induced 14 | -0.030455 |
| FAM20C | family with sequence similarity 20, member C | -0.0302698 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0292689 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0291768 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0289744 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0287559 |
| ADIPOR2 | adiponectin receptor 2 | -0.0284633 |
| UBC | ubiquitin C | -0.0283428 |
| RBM39 | RNA binding motif protein 39 | -0.0281161 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0280492 |
| KRT81 | keratin 81, type II | -0.0279102 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0277841 |
| CALU | calumenin | -0.0271852 |
| INTS6 | integrator complex subunit 6 | -0.0269335 |
| ETNK1 | ethanolamine kinase 1 | -0.0268661 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | -0.0268232 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0267657 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0260094 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0258652 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0256744 |
| TENM4 | teneurin transmembrane protein 4 | -0.0254699 |
| TMEM165 | transmembrane protein 165 | -0.0251442 |
| PRKCA | protein kinase C, alpha | -0.0250497 |
| INSIG1 | insulin induced gene 1 | -0.0248392 |
| SETD5 | SET domain containing 5 | -0.0248339 |
| RCOR1 | REST corepressor 1 | -0.0248218 |
| EGR1 | early growth response 1 | -0.0241075 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0240404 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0238832 |
| GOLGA3 | golgin A3 | -0.0238687 |
| TNS3 | tensin 3 | -0.0235624 |
| CTSD | cathepsin D | -0.0235045 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0233456 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0233265 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.022819 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0226462 |
| ATN1 | atrophin 1 | -0.022527 |
| CD63 | CD63 molecule | -0.0224806 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0221545 |
| GLG1 | golgi glycoprotein 1 | -0.021549 |
| NAV2 | neuron navigator 2 | -0.0211028 |
| FNIP1 | folliculin interacting protein 1 | -0.0210729 |
| NUMB | numb homolog (Drosophila) | -0.0205416 |
| HELZ | helicase with zinc finger | -0.0204217 |
| GPATCH2L | G patch domain containing 2-like | -0.020396 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0201947 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0200856 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0199473 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0198755 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0197864 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0197648 |
| TUFT1 | tuftelin 1 | -0.0195394 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0194585 |
| PCNX4 | pecanex 4 | -0.019162 |
| SETX | senataxin | -0.0191477 |
