Tuberculoid Leprosy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A leprosy that results in one erythematous large plaque with well-defined borders that are elevated and that slope down into an atrophic center. (Human Disease Ontology, DOID_1025)
External Link https://www.disgenet.org/browser/0/1/0/C0023351
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Genes

32 genes associated with the disease Tuberculoid Leprosy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD40LG CD40 ligand
CDKN2A cyclin-dependent kinase inhibitor 2A
FLNB filamin B, beta
GEM GTP binding protein overexpressed in skeletal muscle
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HP haptoglobin
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
IL12RB2 interleukin 12 receptor, beta 2
IL17A interleukin 17A
IL18 interleukin 18
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NXF1 nuclear RNA export factor 1
S100A6 S100 calcium binding protein A6
SEC14L2 SEC14-like 2 (S. cerevisiae)
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TFRC transferrin receptor
TNF tumor necrosis factor
USO1 USO1 vesicle transport factor
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor