| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.128249 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.117833 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.10985 |
| POTEF | POTE ankyrin domain family, member F | 0.0701518 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0692226 |
| TPM3 | tropomyosin 3 | 0.0663865 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0613429 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0604653 |
| DST | dystonin | 0.0603394 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0585545 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0576376 |
| LDHA | lactate dehydrogenase A | 0.0565815 |
| FLNB | filamin B, beta | 0.0538938 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0533394 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0528844 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0510697 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0500534 |
| NAV2 | neuron navigator 2 | 0.0478885 |
| ACTG1 | actin gamma 1 | 0.0451856 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0444968 |
| SEPTIN9 | septin 9 | 0.0430594 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0421971 |
| APP | amyloid beta (A4) precursor protein | 0.0397712 |
| AHNAK | AHNAK nucleoprotein | 0.0396703 |
| THBS2 | thrombospondin 2 | 0.0395608 |
| RUNX1 | runt-related transcription factor 1 | 0.0394929 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0369993 |
| OGA | O-GlcNAcase | 0.0367924 |
| ARRDC3 | arrestin domain containing 3 | 0.0360834 |
| MSN | moesin | 0.0345456 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0338768 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0335772 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0324864 |
| COL3A1 | collagen, type III, alpha 1 | 0.0316516 |
| MYOF | myoferlin | 0.0316163 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.031359 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.031242 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0301975 |
| FSTL1 | follistatin-like 1 | 0.030168 |
| ATP13A3 | ATPase type 13A3 | 0.0300034 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0298679 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0297334 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0291251 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.029111 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0289911 |
| PCBP2 | poly(rC) binding protein 2 | 0.0289122 |
| FNIP1 | folliculin interacting protein 1 | 0.0288833 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0287488 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.028741 |
| COL5A2 | collagen, type V, alpha 2 | 0.028637 |
| NAV1 | neuron navigator 1 | 0.0286286 |
| COPA | coatomer protein complex, subunit alpha | 0.0286157 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.028498 |
| HDAC9 | histone deacetylase 9 | 0.0282435 |
| CD44 | CD44 molecule (Indian blood group) | 0.0281911 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.028047 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0275684 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0273534 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0273322 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0271909 |
| ASPH | aspartate beta-hydroxylase | 0.0269557 |
| RRM2 | ribonucleotide reductase M2 | 0.0265106 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0265041 |
| SBF2 | SET binding factor 2 | 0.026465 |
| CENPF | centromere protein F, 350/400kDa | 0.0264028 |
| NEK7 | NIMA-related kinase 7 | 0.0263637 |
| GLIS3 | GLIS family zinc finger 3 | 0.0262353 |
| ERBIN | erbb2 interacting protein | 0.0259615 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0258878 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0256124 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0255528 |
| SQSTM1 | sequestosome 1 | 0.0254918 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0254717 |
| ADAR | adenosine deaminase, RNA-specific | 0.0254663 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0253652 |
| ANXA2 | annexin A2 | 0.0252867 |
| AUTS2 | autism susceptibility candidate 2 | 0.0249415 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0248734 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0248668 |
| PRELID2 | PRELI domain containing 2 | 0.0248503 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0248395 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0247494 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0245831 |
| SUCO | SUN domain containing ossification factor | 0.0244831 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0241985 |
| PTK2 | protein tyrosine kinase 2 | 0.0241085 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0240818 |
| DSPP | dentin sialophosphoprotein | 0.0239985 |
| RTN4 | reticulon 4 | 0.023938 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0239106 |
| GPC6 | glypican 6 | 0.0238995 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0238314 |
| ATXN1 | ataxin 1 | 0.0237999 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0237945 |
| FBN1 | fibrillin 1 | 0.023617 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.023564 |
| XPO1 | exportin 1 | 0.0235359 |
| HELZ | helicase with zinc finger | 0.0233869 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0231465 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0230398 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.270792 |
| TMSB10 | thymosin beta 10 | -0.172543 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.159255 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.086094 |
| CSTB | cystatin B (stefin B) | -0.0856004 |
| S100A10 | S100 calcium binding protein A10 | -0.0828348 |
| MT2A | metallothionein 2A | -0.0809423 |
| PLAT | plasminogen activator, tissue | -0.0742343 |
| FN1 | fibronectin 1 | -0.0638585 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.059393 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0511141 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0502975 |
| SUCNR1 | succinate receptor 1 | -0.049653 |
| S100A6 | S100 calcium binding protein A6 | -0.0486593 |
| PODXL | podocalyxin-like | -0.0480329 |
| PTMA | prothymosin, alpha | -0.0479581 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.047636 |
| HLA-B | major histocompatibility complex, class I, B | -0.0467887 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0462202 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0384461 |
| RPS24 | ribosomal protein S24 | -0.0361867 |
| LMNA | lamin A/C | -0.0349878 |
| RPL37A | ribosomal protein L37a | -0.0347412 |
| RPL35A | ribosomal protein L35a | -0.034423 |
| PRSS23 | protease, serine, 23 | -0.0327324 |
| S100A11 | S100 calcium binding protein A11 | -0.0324545 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0316658 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0308925 |
| FTL | ferritin, light polypeptide | -0.0302776 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0298417 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0286572 |
| RPLP2 | ribosomal protein, large, P2 | -0.0284708 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0283173 |
| RPL28 | ribosomal protein L28 | -0.0282272 |
| RPS8 | ribosomal protein S8 | -0.0269003 |
| RPS19 | ribosomal protein S19 | -0.0260193 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0258332 |
| HLA-C | major histocompatibility complex, class I, C | -0.0256874 |
| SEC61G | Sec61 gamma subunit | -0.025528 |
| RPS27A | ribosomal protein S27a | -0.0247098 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0245699 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0242653 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0241874 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0238676 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0234216 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0232101 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0230616 |
| RPL34 | ribosomal protein L34 | -0.0229424 |
| RPLP1 | ribosomal protein, large, P1 | -0.0229039 |
| CAVIN1 | caveolae associated protein 1 | -0.0226371 |
| RPS15 | ribosomal protein S15 | -0.0223972 |
| NDRG1 | N-myc downstream regulated 1 | -0.0222274 |
| CCND1 | cyclin D1 | -0.0222263 |
| KRT81 | keratin 81, type II | -0.0217919 |
| S100A9 | S100 calcium binding protein A9 | -0.0214264 |
| RPS27 | ribosomal protein S27 | -0.0214109 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0213597 |
| S100A4 | S100 calcium binding protein A4 | -0.0211526 |
| RPL36 | ribosomal protein L36 | -0.020961 |
| TPM1 | tropomyosin 1 (alpha) | -0.0208925 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0197185 |
| RPS23 | ribosomal protein S23 | -0.0194255 |
| HLA-A | major histocompatibility complex, class I, A | -0.0191693 |
| RPS13 | ribosomal protein S13 | -0.0190389 |
| RPS6 | ribosomal protein S6 | -0.019024 |
| RPS14 | ribosomal protein S14 | -0.0186966 |
| RPL9 | ribosomal protein L9 | -0.0185288 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0183269 |
| RRBP1 | ribosome binding protein 1 | -0.0182712 |
| RPS3 | ribosomal protein S3 | -0.0181071 |
| RPS12 | ribosomal protein S12 | -0.0179857 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.017692 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0176334 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0174082 |
| RPL12 | ribosomal protein L12 | -0.0169876 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0169314 |
| GNAS | GNAS complex locus | -0.0168704 |
| LRRC17 | leucine rich repeat containing 17 | -0.0163573 |
| RPL31 | ribosomal protein L31 | -0.0161087 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0160901 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0159228 |
| RPS21 | ribosomal protein S21 | -0.0157916 |
| PFN1 | profilin 1 | -0.0157314 |
| CD81 | CD81 molecule | -0.0155886 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0155699 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0155319 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0155264 |
| RPS25 | ribosomal protein S25 | -0.0154852 |
| FRMD4A | FERM domain containing 4A | -0.015445 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0152264 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0150753 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0149214 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0147633 |
| RPL38 | ribosomal protein L38 | -0.0146385 |
| IL7R | interleukin 7 receptor | -0.0145013 |
| LOX | lysyl oxidase | -0.0144747 |
| TAGLN2 | transgelin 2 | -0.0141849 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.013881 |
| TUBB | tubulin, beta class I | -0.0138005 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0135967 |
