| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tubulin inhibitor 6_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.227166 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.175998 |
| FLNB | filamin B, beta | 0.164939 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.113572 |
| AHNAK | AHNAK nucleoprotein | 0.113407 |
| SDC4 | syndecan 4 | 0.112296 |
| POTEF | POTE ankyrin domain family, member F | 0.102297 |
| EFNA5 | ephrin-A5 | 0.101141 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.098676 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0969466 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0965209 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0891084 |
| NDRG1 | N-myc downstream regulated 1 | 0.0868277 |
| TPM3 | tropomyosin 3 | 0.0816542 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0808696 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0808239 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0793893 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0738372 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0691667 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0677362 |
| DSPP | dentin sialophosphoprotein | 0.0671029 |
| PLEC | plectin | 0.065997 |
| RIOK3 | RIO kinase 3 | 0.0657497 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0639757 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0629309 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0626106 |
| SMAD3 | SMAD family member 3 | 0.0611389 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0604503 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0595195 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0579864 |
| EZR | ezrin | 0.0576826 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0569507 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0564994 |
| ACTG1 | actin gamma 1 | 0.0540497 |
| PMM2 | phosphomannomutase 2 | 0.0538261 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0537082 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0526467 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0514122 |
| BMP6 | bone morphogenetic protein 6 | 0.0507492 |
| MMP1 | matrix metallopeptidase 1 | 0.0504825 |
| DSG2 | desmoglein 2 | 0.0496105 |
| UBC | ubiquitin C | 0.0495779 |
| MED13L | mediator complex subunit 13-like | 0.0491565 |
| SGMS2 | sphingomyelin synthase 2 | 0.0481474 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0479571 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0476839 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0476206 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0471588 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0470942 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0463959 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0461775 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0452909 |
| RCOR1 | REST corepressor 1 | 0.0451581 |
| FAM107B | family with sequence similarity 107, member B | 0.0448836 |
| ATP13A3 | ATPase type 13A3 | 0.0439776 |
| CALU | calumenin | 0.0437352 |
| CORO1C | coronin, actin binding protein, 1C | 0.0432702 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.043099 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0416157 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0413363 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0410896 |
| VIM | vimentin | 0.0410566 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.040794 |
| RAB10 | RAB10, member RAS oncogene family | 0.0407235 |
| TXNRD1 | thioredoxin reductase 1 | 0.0406853 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0405585 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0404992 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0395777 |
| OXSR1 | oxidative stress responsive 1 | 0.0395722 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0390481 |
| SEPTIN9 | septin 9 | 0.0387344 |
| DIAPH1 | diaphanous-related formin 1 | 0.0380628 |
| ANXA2 | annexin A2 | 0.0375186 |
| JMJD1C | jumonji domain containing 1C | 0.0370543 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0366905 |
| PCBP2 | poly(rC) binding protein 2 | 0.0365725 |
| CAPRIN2 | caprin family member 2 | 0.0364814 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0364501 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0363693 |
| RTN4 | reticulon 4 | 0.0361471 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0358084 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0357723 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0356845 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0348453 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0347025 |
| PARD3 | par-3 family cell polarity regulator | 0.0344425 |
| ITGA6 | integrin, alpha 6 | 0.0344203 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0343342 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0342754 |
| SEPTIN10 | septin 10 | 0.0342258 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.034202 |
| LDHA | lactate dehydrogenase A | 0.0341943 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0341928 |
| ARRDC3 | arrestin domain containing 3 | 0.0340622 |
| CDCP1 | CUB domain containing protein 1 | 0.0337276 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0335853 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0332341 |
| OGA | O-GlcNAcase | 0.0332071 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0330311 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0328823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.158737 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.116141 |
| RPL37A | ribosomal protein L37a | -0.105005 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0964282 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0871825 |
| LAMA4 | laminin, alpha 4 | -0.0795559 |
| NPSR1 | neuropeptide S receptor 1 | -0.0736888 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0661568 |
| RPS3 | ribosomal protein S3 | -0.0655709 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.06555 |
| RPS12 | ribosomal protein S12 | -0.0638498 |
| LMO7 | LIM domain 7 | -0.0630398 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0613971 |
| HDAC9 | histone deacetylase 9 | -0.060734 |
| HMGA1 | high mobility group AT-hook 1 | -0.0606243 |
| RPL35A | ribosomal protein L35a | -0.0570716 |
| RPLP2 | ribosomal protein, large, P2 | -0.0562381 |
| VCAN | versican | -0.0503275 |
| RPS25 | ribosomal protein S25 | -0.0479724 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0469087 |
| RPS23 | ribosomal protein S23 | -0.0468403 |
| RPS8 | ribosomal protein S8 | -0.0468177 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0456145 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0440544 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0431583 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.043013 |
| RPS27A | ribosomal protein S27a | -0.042477 |
| MUC17 | mucin 17, cell surface associated | -0.042035 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0419987 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.041506 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0412522 |
| RPS29 | ribosomal protein S29 | -0.0402694 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0400749 |
| MXD1 | MAX dimerization protein 1 | -0.0398093 |
| RPS24 | ribosomal protein S24 | -0.039464 |
| RPS13 | ribosomal protein S13 | -0.0389023 |
| RPLP1 | ribosomal protein, large, P1 | -0.0378938 |
| RPL9 | ribosomal protein L9 | -0.0371841 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0360958 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0351226 |
| KLK10 | kallikrein-related peptidase 10 | -0.0347041 |
| UPP1 | uridine phosphorylase 1 | -0.0343098 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | -0.0330778 |
| RPL28 | ribosomal protein L28 | -0.0327268 |
| RAD51B | RAD51 paralog B | -0.0321481 |
| PERP | PERP, TP53 apoptosis effector | -0.0318855 |
| RPL26 | ribosomal protein L26 | -0.0314638 |
| RPL36A | ribosomal protein L36a | -0.0313245 |
| RPS6 | ribosomal protein S6 | -0.0311068 |
| TMSB10 | thymosin beta 10 | -0.0308098 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0308048 |
| RPL37 | ribosomal protein L37 | -0.0305935 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0303917 |
| RPL38 | ribosomal protein L38 | -0.0294458 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0292879 |
| ZC3H3 | zinc finger CCCH-type containing 3 | -0.0291979 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0290836 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0286565 |
| RNF213 | ring finger protein 213 | -0.0284957 |
| NBEAL1 | neurobeachin-like 1 | -0.0283982 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0281936 |
| RPL36 | ribosomal protein L36 | -0.0281822 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.027422 |
| INTS6 | integrator complex subunit 6 | -0.0271054 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0268962 |
| DIAPH2 | diaphanous-related formin 2 | -0.0268393 |
| RPS14 | ribosomal protein S14 | -0.0265871 |
| RPL30 | ribosomal protein L30 | -0.0263825 |
| RPS20 | ribosomal protein S20 | -0.0261614 |
| RPL11 | ribosomal protein L11 | -0.0260083 |
| RPS19 | ribosomal protein S19 | -0.0259737 |
| S100A11 | S100 calcium binding protein A11 | -0.0259535 |
| RPS21 | ribosomal protein S21 | -0.0257684 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0256907 |
| FERMT1 | fermitin family member 1 | -0.0256343 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0254177 |
| GNAS | GNAS complex locus | -0.0252166 |
| RPL12 | ribosomal protein L12 | -0.0248262 |
| TGFA | transforming growth factor, alpha | -0.0239813 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0236006 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0235556 |
| RPS11 | ribosomal protein S11 | -0.0233298 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0228667 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0228352 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0227456 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0226576 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0225992 |
| MT2A | metallothionein 2A | -0.0221494 |
| RPS27 | ribosomal protein S27 | -0.0220109 |
| LAMB3 | laminin, beta 3 | -0.0219858 |
| RIGI | RNA sensor RIG-I | -0.0217872 |
| RPL7A | ribosomal protein L7a | -0.0217317 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0216834 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0215703 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0213386 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0213337 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.021092 |
| PLSCR1 | phospholipid scramblase 1 | -0.020942 |
| EXOC4 | exocyst complex component 4 | -0.0207214 |
| RPL31 | ribosomal protein L31 | -0.0206291 |
