| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.27932 |
| EXT1 | exostosin glycosyltransferase 1 | 0.175827 |
| NRG1 | neuregulin 1 | 0.162726 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.153847 |
| LSAMP | limbic system-associated membrane protein | 0.14498 |
| TLE4 | transducin-like enhancer of split 4 | 0.136303 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.12684 |
| ACTG1 | actin gamma 1 | 0.113475 |
| BPTF | bromodomain PHD finger transcription factor | 0.0887406 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0872688 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0852627 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0841217 |
| SYT1 | synaptotagmin I | 0.0825949 |
| FMN1 | formin 1 | 0.0822602 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0797326 |
| NPAS2 | neuronal PAS domain protein 2 | 0.078727 |
| VMP1 | vacuole membrane protein 1 | 0.0779583 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0775735 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0774591 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0750406 |
| GLCCI1 | glucocorticoid induced 1 | 0.074986 |
| STK38L | serine/threonine kinase 38 like | 0.0741706 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0727228 |
| SIK2 | salt-inducible kinase 2 | 0.0705449 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0698067 |
| PRKCA | protein kinase C, alpha | 0.0671459 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0671121 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0667193 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0647677 |
| KLHL13 | kelch-like family member 13 | 0.0645121 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0626787 |
| DST | dystonin | 0.062332 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.061884 |
| ZNF804A | zinc finger protein 804A | 0.061523 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0606306 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0601982 |
| FERMT2 | fermitin family member 2 | 0.0580978 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0571144 |
| INTS6 | integrator complex subunit 6 | 0.0570202 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0560131 |
| PDE10A | phosphodiesterase 10A | 0.0552254 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0548524 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0547053 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0541007 |
| SIK3 | SIK family kinase 3 | 0.0537421 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0536976 |
| TPM1 | tropomyosin 1 (alpha) | 0.0530933 |
| TPM4 | tropomyosin 4 | 0.0530899 |
| MEF2A | myocyte enhancer factor 2A | 0.0528352 |
| PLPP1 | phospholipid phosphatase 1 | 0.0525141 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0520148 |
| PLAT | plasminogen activator, tissue | 0.0514051 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0513691 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0512252 |
| PCBP2 | poly(rC) binding protein 2 | 0.0511355 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0508281 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.050462 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0486585 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0481071 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0473437 |
| HOMER1 | homer scaffolding protein 1 | 0.0472675 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0472064 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0457311 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0445903 |
| SYNPO2 | synaptopodin 2 | 0.0444533 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0443923 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0440904 |
| DGKH | diacylglycerol kinase, eta | 0.0431498 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0429129 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0428074 |
| ATXN1 | ataxin 1 | 0.0420539 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0415203 |
| CALD1 | caldesmon 1 | 0.0412878 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0408875 |
| EXOC4 | exocyst complex component 4 | 0.040739 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0407058 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0406668 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0401297 |
| MED13 | mediator complex subunit 13 | 0.0401289 |
| COL3A1 | collagen, type III, alpha 1 | 0.0399112 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0398125 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0393517 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0387279 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0385924 |
| MYO1E | myosin IE | 0.0384188 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0384103 |
| MYO6 | myosin VI | 0.0383754 |
| RPS12 | ribosomal protein S12 | 0.0383532 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0382351 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.038019 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0377346 |
| RPS3 | ribosomal protein S3 | 0.0375379 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0375185 |
| NBEA | neurobeachin | 0.0369787 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0369531 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0367407 |
| RAD51B | RAD51 paralog B | 0.0367342 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0365443 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0356276 |
| CUX1 | cut-like homeobox 1 | 0.035541 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.148095 |
| IGF2 | insulin-like growth factor 2 | -0.0453418 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0273208 |
| TRIB2 | tribbles pseudokinase 2 | -0.0265063 |
| USP3 | ubiquitin specific peptidase 3 | -0.0258334 |
| NDRG1 | N-myc downstream regulated 1 | -0.0257588 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0250725 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0242733 |
| MATR3 | matrin 3 | -0.0222372 |
| CDC27 | cell division cycle 27 | -0.0218197 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0216658 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0212879 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0211846 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0203293 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0199944 |
| FOXK2 | forkhead box K2 | -0.019791 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.019758 |
| ANXA2 | annexin A2 | -0.0196829 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0188502 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0186202 |
| FTL | ferritin, light polypeptide | -0.0186006 |
| GNAS | GNAS complex locus | -0.0183534 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0175807 |
| RPL38 | ribosomal protein L38 | -0.0171674 |
| TMSB10 | thymosin beta 10 | -0.0170574 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0169371 |
| HELZ | helicase with zinc finger | -0.0167144 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0165911 |
| NPR2 | natriuretic peptide receptor 2 | -0.016161 |
| VIM | vimentin | -0.015957 |
| PRSS3 | protease, serine, 3 | -0.0158644 |
| SEPTIN2 | septin 2 | -0.0155747 |
| PTMA | prothymosin, alpha | -0.0154668 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0154658 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0154574 |
| RTN4 | reticulon 4 | -0.0150501 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0149488 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0149434 |
| XPO1 | exportin 1 | -0.0149199 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0146693 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0146671 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0146149 |
| MXI1 | MAX interactor 1, dimerization protein | -0.014123 |
| TPX2 | TPX2, microtubule-associated | -0.013769 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0137057 |
| ECT2 | epithelial cell transforming 2 | -0.0136484 |
| DIAPH3 | diaphanous-related formin 3 | -0.0136406 |
| HMGA1 | high mobility group AT-hook 1 | -0.0135254 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0134297 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0133849 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0133733 |
| STK17A | serine/threonine kinase 17a | -0.0132171 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0131247 |
| WDR36 | WD repeat domain 36 | -0.0131098 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0131064 |
| CENPF | centromere protein F, 350/400kDa | -0.0130877 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0130381 |
| GPHN | gephyrin | -0.0130203 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0130184 |
| NEK7 | NIMA-related kinase 7 | -0.0129062 |
| RPL32 | ribosomal protein L32 | -0.012827 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0128028 |
| RNF149 | ring finger protein 149 | -0.0127903 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0127365 |
| NGLY1 | N-glycanase 1 | -0.0126502 |
| CCND1 | cyclin D1 | -0.0126492 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0125636 |
| MKI67 | marker of proliferation Ki-67 | -0.0125606 |
| TKT | transketolase | -0.0125495 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0125176 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0124698 |
| BTG3 | BTG family, member 3 | -0.0124635 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0124529 |
| RGS4 | regulator of G-protein signaling 4 | -0.0122894 |
| GSPT1 | G1 to S phase transition 1 | -0.0121369 |
| PRR11 | proline rich 11 | -0.0120863 |
| RNF24 | ring finger protein 24 | -0.0120096 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.011977 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0119422 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0119409 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0119383 |
| TCERG1 | transcription elongation regulator 1 | -0.0119343 |
| H1-0 | H1.0 linker histone | -0.0117561 |
| HAS2 | hyaluronan synthase 2 | -0.0117141 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0116766 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0115822 |
| NUP54 | nucleoporin 54kDa | -0.0115579 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.011493 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0114762 |
| BLTP3B | bridge-like lipid transfer protein family member 3B | -0.0113948 |
| WDR48 | WD repeat domain 48 | -0.0113921 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0113828 |
| FHIP2A | FHF complex subunit HOOK interacting protein 2A | -0.011245 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -0.0111731 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0111064 |
| UBB | ubiquitin B | -0.0110317 |
| TNPO1 | transportin 1 | -0.0109801 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0109699 |
| WDR43 | WD repeat domain 43 | -0.0109509 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0109495 |
