| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.103635 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0909242 |
| ASPH | aspartate beta-hydroxylase | 0.0902232 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0826895 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0779134 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.06291 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0627441 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0621261 |
| HDAC9 | histone deacetylase 9 | 0.0598518 |
| SDC4 | syndecan 4 | 0.0544168 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0516172 |
| FNIP1 | folliculin interacting protein 1 | 0.0506531 |
| STC1 | stanniocalcin 1 | 0.0467725 |
| COL5A1 | collagen, type V, alpha 1 | 0.0459458 |
| GOLGB1 | golgin B1 | 0.0458373 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0442238 |
| KYNU | kynureninase | 0.043277 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0424197 |
| VEGFA | vascular endothelial growth factor A | 0.0418059 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0412735 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0411535 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0385056 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0378488 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0369297 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.036624 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.03531 |
| PRELID2 | PRELI domain containing 2 | 0.0347936 |
| TPM3 | tropomyosin 3 | 0.0333487 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0332985 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0317239 |
| DTNA | dystrobrevin, alpha | 0.0312684 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0311909 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0306775 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0302373 |
| INTS6 | integrator complex subunit 6 | 0.0302169 |
| CANX | calnexin | 0.0300919 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.030036 |
| FAM219A | family with sequence similarity 219, member A | 0.0298079 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0293764 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0290429 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0287507 |
| PMM2 | phosphomannomutase 2 | 0.0285004 |
| ZNF395 | zinc finger protein 395 | 0.0284849 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0280347 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0277249 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0269101 |
| RUNX1 | runt-related transcription factor 1 | 0.0267541 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0264377 |
| ZNF841 | zinc finger protein 841 | 0.0257864 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0256716 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0256365 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0255398 |
| PGM3 | phosphoglucomutase 3 | 0.0254503 |
| GPATCH2L | G patch domain containing 2-like | 0.0253965 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0253021 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0250019 |
| B2M | beta-2-microglobulin | 0.0239517 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.023893 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.023696 |
| SRP54 | signal recognition particle 54kDa | 0.0233311 |
| SPMIP6 | sperm microtubule inner protein 6 | 0.0232897 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0231839 |
| MYO9A | myosin IXA | 0.0231119 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0230444 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.022962 |
| SCFD1 | sec1 family domain containing 1 | 0.0228255 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0226139 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.022356 |
| STXBP1 | syntaxin binding protein 1 | 0.0222897 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0217244 |
| UBAP2 | ubiquitin associated protein 2 | 0.0216744 |
| COG6 | component of oligomeric golgi complex 6 | 0.0216182 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0215782 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.021298 |
| C1S | complement component 1, s subcomponent | 0.0212808 |
| PCBP3 | poly(rC) binding protein 3 | 0.0211584 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0210012 |
| PCBP2 | poly(rC) binding protein 2 | 0.0207816 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0206179 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.020562 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0203938 |
| ZNF432 | zinc finger protein 432 | 0.0201187 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0199874 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0199262 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0197294 |
| SEC24D | SEC24 family member D | 0.0195756 |
| ZNF638 | zinc finger protein 638 | 0.0195406 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0194314 |
| GLRX | glutaredoxin (thioltransferase) | 0.0194258 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0191828 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0189909 |
| HYOU1 | hypoxia up-regulated 1 | 0.0188023 |
| FAM13A | family with sequence similarity 13, member A | 0.0185811 |
| COPA | coatomer protein complex, subunit alpha | 0.0185183 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0183906 |
| USO1 | USO1 vesicle transport factor | 0.0183288 |
| PHF3 | PHD finger protein 3 | 0.01827 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0180976 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0180683 |
| APP | amyloid beta (A4) precursor protein | 0.0180095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.214762 |
| TMSB10 | thymosin beta 10 | -0.195613 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.162317 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.15947 |
| VIM | vimentin | -0.130706 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.107193 |
| FN1 | fibronectin 1 | -0.102716 |
| PTMA | prothymosin, alpha | -0.0974722 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0617839 |
| NDRG1 | N-myc downstream regulated 1 | -0.0545052 |
| TPM4 | tropomyosin 4 | -0.0535972 |
| RPLP1 | ribosomal protein, large, P1 | -0.0517855 |
| MAP1B | microtubule-associated protein 1B | -0.05052 |
| MKI67 | marker of proliferation Ki-67 | -0.0495578 |
| ANXA2 | annexin A2 | -0.0494316 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0473785 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.047274 |
| TXNRD1 | thioredoxin reductase 1 | -0.046076 |
| TUBB | tubulin, beta class I | -0.0441039 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0430165 |
| RPL35A | ribosomal protein L35a | -0.0426795 |
| PKM | pyruvate kinase, muscle | -0.0415261 |
| RPS24 | ribosomal protein S24 | -0.0409982 |
| TPI1 | triosephosphate isomerase 1 | -0.0384731 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.037615 |
| GNAS | GNAS complex locus | -0.0375274 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0374199 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0373548 |
| DST | dystonin | -0.0365072 |
| TNNC1 | troponin C type 1 (slow) | -0.0362515 |
| S100A10 | S100 calcium binding protein A10 | -0.0357616 |
| RPL28 | ribosomal protein L28 | -0.0353633 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0347759 |
| RPLP2 | ribosomal protein, large, P2 | -0.0346454 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0337456 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0334955 |
| RPL31 | ribosomal protein L31 | -0.0326384 |
| RPS13 | ribosomal protein S13 | -0.0326303 |
| RPS8 | ribosomal protein S8 | -0.0322604 |
| H3-3B | H3.3 histone B | -0.0322395 |
| RPS6 | ribosomal protein S6 | -0.0314097 |
| PGK1 | phosphoglycerate kinase 1 | -0.030683 |
| RPL34 | ribosomal protein L34 | -0.0302671 |
| ANLN | anillin, actin binding protein | -0.0297818 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0296415 |
| HMGA1 | high mobility group AT-hook 1 | -0.0296389 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0295821 |
| IGF2 | insulin-like growth factor 2 | -0.0292466 |
| SEPTIN7 | septin 7 | -0.0289479 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.028825 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0288142 |
| SBF2 | SET binding factor 2 | -0.0287362 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0287196 |
| RPS23 | ribosomal protein S23 | -0.0284778 |
| S100A6 | S100 calcium binding protein A6 | -0.0279675 |
| STK17A | serine/threonine kinase 17a | -0.0278714 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0275934 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0275495 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0272661 |
| RPS25 | ribosomal protein S25 | -0.0265498 |
| RPS19 | ribosomal protein S19 | -0.026536 |
| INHBA | inhibin, beta A | -0.0264574 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0263886 |
| LMNA | lamin A/C | -0.0263811 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0262241 |
| PTCHD4 | patched domain containing 4 | -0.0257906 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0249219 |
| RPL38 | ribosomal protein L38 | -0.0249099 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0248215 |
| IER3 | immediate early response 3 | -0.0247881 |
| MAP4 | microtubule-associated protein 4 | -0.0246615 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0242315 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0235931 |
| CENPF | centromere protein F, 350/400kDa | -0.0235436 |
| RPL11 | ribosomal protein L11 | -0.023376 |
| NLGN1 | neuroligin 1 | -0.0231285 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0230489 |
| RPL37A | ribosomal protein L37a | -0.0228767 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0228129 |
| NAV3 | neuron navigator 3 | -0.0228064 |
| RPS5 | ribosomal protein S5 | -0.0224707 |
| USP3 | ubiquitin specific peptidase 3 | -0.0223967 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0220833 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0219315 |
| RPL9 | ribosomal protein L9 | -0.0216418 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0216255 |
| RPL23 | ribosomal protein L23 | -0.0215421 |
| CENPE | centromere protein E, 312kDa | -0.021447 |
| RPL32 | ribosomal protein L32 | -0.0214039 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0214014 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0212477 |
| PRRC2C | proline-rich coiled-coil 2C | -0.021247 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0209808 |
| CBX3 | chromobox homolog 3 | -0.0209507 |
| RTN4 | reticulon 4 | -0.0209338 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0208982 |
| CAVIN1 | caveolae associated protein 1 | -0.0208125 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0206537 |
| RPS27A | ribosomal protein S27a | -0.0199689 |
| RRBP1 | ribosome binding protein 1 | -0.0197517 |
