| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.134081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.123663 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0582874 |
| POTEF | POTE ankyrin domain family, member F | 0.0579403 |
| KRT8 | keratin 8, type II | 0.0555768 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0477053 |
| INTS6 | integrator complex subunit 6 | 0.0452004 |
| TPM3 | tropomyosin 3 | 0.0411482 |
| SDC4 | syndecan 4 | 0.0411347 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0410025 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.039462 |
| VEGFA | vascular endothelial growth factor A | 0.0372088 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0346911 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0338751 |
| ENO1 | enolase 1, (alpha) | 0.0337617 |
| LDHA | lactate dehydrogenase A | 0.0335074 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0327406 |
| FNIP1 | folliculin interacting protein 1 | 0.0324578 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0318714 |
| DSPP | dentin sialophosphoprotein | 0.0314929 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0314402 |
| GOLGB1 | golgin B1 | 0.0308266 |
| HDLBP | high density lipoprotein binding protein | 0.0300427 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0279975 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0275794 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0273292 |
| SEC24D | SEC24 family member D | 0.0272938 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0256946 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0246489 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0244093 |
| ACTG1 | actin gamma 1 | 0.0238807 |
| RRM2 | ribonucleotide reductase M2 | 0.0237772 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0232276 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0229991 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0228117 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0226649 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0225612 |
| KRT18 | keratin 18, type I | 0.0222377 |
| TLN1 | talin 1 | 0.0217675 |
| POU2F2 | POU class 2 homeobox 2 | 0.0216604 |
| HOMER1 | homer scaffolding protein 1 | 0.0211151 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0208998 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0207347 |
| ARRDC3 | arrestin domain containing 3 | 0.0206374 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.0205817 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.02012 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0200383 |
| HELZ | helicase with zinc finger | 0.0196322 |
| RPS12 | ribosomal protein S12 | 0.0194926 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0194905 |
| FOXO3 | forkhead box O3 | 0.0193947 |
| CLU | clusterin | 0.0193745 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0191241 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0190766 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0189079 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0188127 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0185712 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0185645 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0183015 |
| GOLGA2 | golgin A2 | 0.0181491 |
| MACROD2 | MACRO domain containing 2 | 0.0178779 |
| KAZN | kazrin, periplakin interacting protein | 0.0175861 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.017428 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0173376 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0172042 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0170399 |
| ZNF292 | zinc finger protein 292 | 0.0169689 |
| SEPTIN9 | septin 9 | 0.0165148 |
| ATXN1 | ataxin 1 | 0.016293 |
| CANX | calnexin | 0.0161727 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0159403 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0158447 |
| PGM3 | phosphoglucomutase 3 | 0.0157168 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0155643 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0155388 |
| ADD1 | adducin 1 (alpha) | 0.0152796 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0150514 |
| TJP1 | tight junction protein 1 | 0.0146837 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0145481 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0143923 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0143454 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0142765 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0142242 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0139726 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0139429 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0139123 |
| CNN3 | calponin 3, acidic | 0.0138739 |
| CCNYL1 | cyclin Y-like 1 | 0.0137641 |
| SET | SET nuclear proto-oncogene | 0.0135856 |
| DIAPH1 | diaphanous-related formin 1 | 0.0134205 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.013389 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0133852 |
| TGFB1 | transforming growth factor, beta 1 | 0.013358 |
| GOLT1B | golgi transport 1B | 0.0132459 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0131554 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0130844 |
| SSR1 | signal sequence receptor, alpha | 0.01301 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0129835 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0129804 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0129615 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.246679 |
| TMSB10 | thymosin beta 10 | -0.209912 |
| PTMA | prothymosin, alpha | -0.184862 |
| PKM | pyruvate kinase, muscle | -0.064686 |
| RPS6 | ribosomal protein S6 | -0.0641251 |
| RPS24 | ribosomal protein S24 | -0.0608787 |
| NDRG1 | N-myc downstream regulated 1 | -0.0590971 |
| UBC | ubiquitin C | -0.0571292 |
| RPLP1 | ribosomal protein, large, P1 | -0.0544159 |
| FTL | ferritin, light polypeptide | -0.0505025 |
| RPS27A | ribosomal protein S27a | -0.0499723 |
| RPL35A | ribosomal protein L35a | -0.0486271 |
| TXNRD1 | thioredoxin reductase 1 | -0.0471715 |
| S100A10 | S100 calcium binding protein A10 | -0.0449631 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0433827 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0414371 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.041134 |
| RPL34 | ribosomal protein L34 | -0.0396658 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0389987 |
| FDPS | farnesyl diphosphate synthase | -0.036443 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0352364 |
| RPL23 | ribosomal protein L23 | -0.0348223 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0342744 |
| RPL31 | ribosomal protein L31 | -0.0342017 |
| RPL32 | ribosomal protein L32 | -0.0325287 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0316335 |
| TUBB4B | tubulin, beta 4B class IVb | -0.031318 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0312089 |
| TPM4 | tropomyosin 4 | -0.0311342 |
| FLNB | filamin B, beta | -0.0308868 |
| LDHB | lactate dehydrogenase B | -0.0306396 |
| GLG1 | golgi glycoprotein 1 | -0.0302878 |
| PERP | PERP, TP53 apoptosis effector | -0.0299916 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0299249 |
| RPL11 | ribosomal protein L11 | -0.0293117 |
| RPS23 | ribosomal protein S23 | -0.02921 |
| FAT1 | FAT atypical cadherin 1 | -0.0291417 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0288492 |
| NF1 | neurofibromin 1 | -0.0287025 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0284993 |
| JMJD1C | jumonji domain containing 1C | -0.0283912 |
| RPS19 | ribosomal protein S19 | -0.0282623 |
| RPS5 | ribosomal protein S5 | -0.028256 |
| GNAS | GNAS complex locus | -0.0282061 |
| TPI1 | triosephosphate isomerase 1 | -0.0280091 |
| HLA-A | major histocompatibility complex, class I, A | -0.0279408 |
| MED13L | mediator complex subunit 13-like | -0.0277187 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0275341 |
| RPS15 | ribosomal protein S15 | -0.0274422 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0274151 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0273102 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0267147 |
| RPL18 | ribosomal protein L18 | -0.0265599 |
| RPL8 | ribosomal protein L8 | -0.0264171 |
| RPS21 | ribosomal protein S21 | -0.0262369 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0260085 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0259289 |
| RPS29 | ribosomal protein S29 | -0.0257669 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0257123 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0253819 |
| RPL5 | ribosomal protein L5 | -0.0253388 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0252868 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0250172 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0248362 |
| S100A9 | S100 calcium binding protein A9 | -0.0246745 |
| RPLP2 | ribosomal protein, large, P2 | -0.0243114 |
| HMGB1 | high mobility group box 1 | -0.0240141 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0239933 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0239382 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.023711 |
| CCND1 | cyclin D1 | -0.0236642 |
| RPL19 | ribosomal protein L19 | -0.0234739 |
| CCNI | cyclin I | -0.0233341 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0232981 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0232887 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0232478 |
| TUBB | tubulin, beta class I | -0.0230167 |
| HMGA1 | high mobility group AT-hook 1 | -0.0229451 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0228745 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.022783 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0226345 |
| NOP58 | NOP58 ribonucleoprotein | -0.0223957 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0222895 |
| MED13 | mediator complex subunit 13 | -0.0222556 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.022182 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0221406 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0221344 |
| MKI67 | marker of proliferation Ki-67 | -0.0220293 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0220247 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0219272 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0219024 |
| ZNF518A | zinc finger protein 518A | -0.0218473 |
| WASF2 | WAS protein family, member 2 | -0.0217689 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0214093 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0213365 |
| ARF4 | ADP-ribosylation factor 4 | -0.0213354 |
| RPL15 | ribosomal protein L15 | -0.0210938 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0210439 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.020935 |
| XPO1 | exportin 1 | -0.0209305 |
