| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.214497 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.162137 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.122481 |
| COL5A1 | collagen, type V, alpha 1 | 0.113099 |
| EXT1 | exostosin glycosyltransferase 1 | 0.113082 |
| HMGA2 | high mobility group AT-hook 2 | 0.109032 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.108679 |
| SEPTIN9 | septin 9 | 0.101331 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.093639 |
| ASPH | aspartate beta-hydroxylase | 0.0882515 |
| MT2A | metallothionein 2A | 0.0827903 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.082216 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0806823 |
| NAV1 | neuron navigator 1 | 0.0799349 |
| AHNAK | AHNAK nucleoprotein | 0.0790801 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0778519 |
| ENO1 | enolase 1, (alpha) | 0.0703858 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0692279 |
| VEGFA | vascular endothelial growth factor A | 0.0681369 |
| ACTG1 | actin gamma 1 | 0.067484 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0658742 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0647155 |
| NAV2 | neuron navigator 2 | 0.0646136 |
| PCBP3 | poly(rC) binding protein 3 | 0.0636867 |
| INTS6 | integrator complex subunit 6 | 0.0625196 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0616073 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0591539 |
| TNS1 | tensin 1 | 0.0580926 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0574732 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0564568 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0555834 |
| HPCAL1 | hippocalcin-like 1 | 0.0554089 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.053372 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0531229 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0520408 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0515307 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0511333 |
| RPS8 | ribosomal protein S8 | 0.0511087 |
| RPS12 | ribosomal protein S12 | 0.0505512 |
| DTNA | dystrobrevin, alpha | 0.0487454 |
| SDC4 | syndecan 4 | 0.0484134 |
| FNIP1 | folliculin interacting protein 1 | 0.0473679 |
| MT1E | metallothionein 1E | 0.0466575 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0451949 |
| SQSTM1 | sequestosome 1 | 0.0450099 |
| GPC5 | glypican 5 | 0.044858 |
| RPS3 | ribosomal protein S3 | 0.0442509 |
| PRELID2 | PRELI domain containing 2 | 0.0433422 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0426403 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0426201 |
| RCOR1 | REST corepressor 1 | 0.0424552 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0418622 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0410148 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0403013 |
| CDH13 | cadherin 13 | 0.0402467 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0398395 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0391652 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0387031 |
| RPL37A | ribosomal protein L37a | 0.0386586 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0383295 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0382259 |
| TGFB1 | transforming growth factor, beta 1 | 0.0381687 |
| PLEC | plectin | 0.0380951 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.037643 |
| RPS6 | ribosomal protein S6 | 0.0371816 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0367605 |
| IL11 | interleukin 11 | 0.0366059 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0362761 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0362648 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0360628 |
| ATXN1 | ataxin 1 | 0.0357719 |
| ANGPTL4 | angiopoietin-like 4 | 0.0357052 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0353698 |
| RUNX1 | runt-related transcription factor 1 | 0.0350495 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0347811 |
| CAPRIN2 | caprin family member 2 | 0.0346311 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0346212 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0340143 |
| PCBP2 | poly(rC) binding protein 2 | 0.0339364 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0339206 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0333933 |
| ZNF638 | zinc finger protein 638 | 0.0330291 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0330169 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0328978 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0323172 |
| GLRX | glutaredoxin (thioltransferase) | 0.0322088 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0320962 |
| RPL37 | ribosomal protein L37 | 0.0317239 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0316138 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.031262 |
| NUMB | numb homolog (Drosophila) | 0.0312584 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0311473 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0310532 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0310256 |
| CANX | calnexin | 0.0308373 |
| GOLGB1 | golgin B1 | 0.0307624 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0304988 |
| SHISA5 | shisa family member 5 | 0.0304056 |
| CLIC4 | chloride intracellular channel 4 | 0.0302909 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0301748 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.275988 |
| VIM | vimentin | -0.230796 |
| TMSB10 | thymosin beta 10 | -0.180273 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.173794 |
| CD44 | CD44 molecule (Indian blood group) | -0.118852 |
| IGF2 | insulin-like growth factor 2 | -0.0931481 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0792287 |
| TENM2 | teneurin transmembrane protein 2 | -0.076817 |
| PTMA | prothymosin, alpha | -0.0685111 |
| GLIS3 | GLIS family zinc finger 3 | -0.0655098 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0626866 |
| EGR1 | early growth response 1 | -0.0579331 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0518888 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0490447 |
| NDRG1 | N-myc downstream regulated 1 | -0.0445932 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0416897 |
| CCND1 | cyclin D1 | -0.038519 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0381884 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0373648 |
| TNNC1 | troponin C type 1 (slow) | -0.0364431 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0347724 |
| PGK1 | phosphoglycerate kinase 1 | -0.0339234 |
| S100A10 | S100 calcium binding protein A10 | -0.0335987 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0328569 |
| OSMR | oncostatin M receptor | -0.0318519 |
| CENPF | centromere protein F, 350/400kDa | -0.0318291 |
| MYO10 | myosin X | -0.0316686 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0313904 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0310119 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0301625 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0297368 |
| TUBB | tubulin, beta class I | -0.0290724 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0290037 |
| RNF24 | ring finger protein 24 | -0.0289276 |
| TPX2 | TPX2, microtubule-associated | -0.0277998 |
| MKI67 | marker of proliferation Ki-67 | -0.0276867 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0268672 |
| RRBP1 | ribosome binding protein 1 | -0.0263277 |
| ANXA2 | annexin A2 | -0.0260349 |
| TAGLN2 | transgelin 2 | -0.0258839 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0257857 |
| SBF2 | SET binding factor 2 | -0.0252397 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0237545 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0237206 |
| TXNIP | thioredoxin interacting protein | -0.023612 |
| KIF14 | kinesin family member 14 | -0.0234688 |
| COL1A1 | collagen, type I, alpha 1 | -0.0233517 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0233395 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0232282 |
| DIAPH3 | diaphanous-related formin 3 | -0.0232115 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0229641 |
| PKM | pyruvate kinase, muscle | -0.0227477 |
| RTN4 | reticulon 4 | -0.0224802 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.022453 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0223424 |
| CENPE | centromere protein E, 312kDa | -0.0220683 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0220494 |
| ANLN | anillin, actin binding protein | -0.0216329 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0216057 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0215016 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0214543 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0204687 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0203761 |
| ACTN4 | actinin, alpha 4 | -0.0202867 |
| PRR11 | proline rich 11 | -0.0201195 |
| USP3 | ubiquitin specific peptidase 3 | -0.01997 |
| ECT2 | epithelial cell transforming 2 | -0.0198745 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0193712 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0187926 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.01856 |
| KIF18B | kinesin family member 18B | -0.0182657 |
| FTL | ferritin, light polypeptide | -0.018178 |
| KIF18A | kinesin family member 18A | -0.0180163 |
| SGO2 | shugoshin 2 | -0.0178805 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0177332 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0175258 |
| RNF149 | ring finger protein 149 | -0.0173855 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.017374 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.017223 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0171832 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0170117 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0169148 |
| LMNA | lamin A/C | -0.0169125 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0168846 |
| WDR45B | WD repeat domain 45B | -0.0167282 |
| KIF4A | kinesin family member 4A | -0.0166188 |
| SYAP1 | synapse associated protein 1 | -0.0165611 |
| HJURP | Holliday junction recognition protein | -0.0162136 |
| MORF4L2 | mortality factor 4 like 2 | -0.0162056 |
| TPI1 | triosephosphate isomerase 1 | -0.0160645 |
| RIN2 | Ras and Rab interactor 2 | -0.0159631 |
| DIAPH2 | diaphanous-related formin 2 | -0.0159343 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0159213 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0157824 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0157702 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0155858 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0154739 |
| FSTL1 | follistatin-like 1 | -0.015399 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0151877 |
| THBS1 | thrombospondin 1 | -0.0149232 |
