| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.175317 |
| SMAD3 | SMAD family member 3 | 0.168212 |
| LMO7 | LIM domain 7 | 0.147057 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.118513 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.103696 |
| ATXN1 | ataxin 1 | 0.102895 |
| INTS6 | integrator complex subunit 6 | 0.100401 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0950161 |
| NTN4 | netrin 4 | 0.0944163 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0811346 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0808682 |
| TJP1 | tight junction protein 1 | 0.0786793 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0752076 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0729831 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0645067 |
| KRT8 | keratin 8, type II | 0.0642094 |
| ACTG1 | actin gamma 1 | 0.0624245 |
| CTBP2 | C-terminal binding protein 2 | 0.062091 |
| AREG | amphiregulin | 0.0599505 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0599358 |
| PRR5L | proline rich 5 like | 0.059804 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0593712 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0557541 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0547277 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0518488 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0516896 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0516523 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0516408 |
| CCNYL1 | cyclin Y-like 1 | 0.0507056 |
| TMEM123 | transmembrane protein 123 | 0.0505786 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0497082 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0496459 |
| TMEM65 | transmembrane protein 65 | 0.0484893 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0478665 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0477612 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0474919 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0468331 |
| VCL | vinculin | 0.0454551 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0446914 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0441763 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.043224 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0419844 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0417922 |
| TLE4 | transducin-like enhancer of split 4 | 0.0417707 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0413766 |
| DST | dystonin | 0.041359 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0412023 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0411379 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0407996 |
| MYO1E | myosin IE | 0.0405942 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0399363 |
| RPS12 | ribosomal protein S12 | 0.0377756 |
| UTRN | utrophin | 0.0377396 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0376299 |
| SERTAD2 | SERTA domain containing 2 | 0.037397 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0368376 |
| PDE10A | phosphodiesterase 10A | 0.036202 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0348817 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.033899 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.032957 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.032718 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0320161 |
| ANXA11 | annexin A11 | 0.0313845 |
| POF1B | premature ovarian failure, 1B | 0.0305004 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0301603 |
| GOLGB1 | golgin B1 | 0.0299922 |
| KRT18 | keratin 18, type I | 0.0299468 |
| MYOF | myoferlin | 0.0298202 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0296636 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0291936 |
| HM13 | histocompatibility (minor) 13 | 0.0287281 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0285194 |
| EREG | epiregulin | 0.0285133 |
| TUFT1 | tuftelin 1 | 0.0284434 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.0281307 |
| POTEF | POTE ankyrin domain family, member F | 0.0279629 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0275099 |
| MAGT1 | magnesium transporter 1 | 0.027487 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0267316 |
| MYZAP | myocardial zonula adherens protein | 0.0264766 |
| VEGFA | vascular endothelial growth factor A | 0.0262255 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0259632 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0259268 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0258834 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0256845 |
| SGMS2 | sphingomyelin synthase 2 | 0.0256048 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0254142 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0250381 |
| RPL35A | ribosomal protein L35a | 0.0249367 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0246285 |
| MYO5B | myosin VB | 0.0244052 |
| UBAP2 | ubiquitin associated protein 2 | 0.0242397 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0241958 |
| GLCCI1 | glucocorticoid induced 1 | 0.0241428 |
| AXIN2 | axin 2 | 0.0240749 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0235791 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0232097 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0226842 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0223944 |
| WLS | wntless Wnt ligand secretion mediator | 0.0222596 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.118949 |
| TMSB10 | thymosin beta 10 | -0.106883 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.104953 |
| PTMA | prothymosin, alpha | -0.104275 |
| EZR | ezrin | -0.100643 |
| FTL | ferritin, light polypeptide | -0.0995406 |
| UBC | ubiquitin C | -0.0917595 |
| TXNRD1 | thioredoxin reductase 1 | -0.0863425 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0722391 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0681776 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0621359 |
| ACTN4 | actinin, alpha 4 | -0.0614323 |
| ANXA2 | annexin A2 | -0.0612701 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0568315 |
| RPS27A | ribosomal protein S27a | -0.0553924 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0546828 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0517831 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0514665 |
| RPLP1 | ribosomal protein, large, P1 | -0.0499411 |
| LYZ | lysozyme | -0.0497433 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0496645 |
| S100A10 | S100 calcium binding protein A10 | -0.0496414 |
| MKI67 | marker of proliferation Ki-67 | -0.0481046 |
| JUN | jun proto-oncogene | -0.0464831 |
| PTK2 | protein tyrosine kinase 2 | -0.0441348 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0439395 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0427847 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0421355 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0420752 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.042046 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.041355 |
| S100A6 | S100 calcium binding protein A6 | -0.0401814 |
| ZNF292 | zinc finger protein 292 | -0.0400536 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0383694 |
| RPL23 | ribosomal protein L23 | -0.0383208 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.037945 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0367796 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0362402 |
| NF1 | neurofibromin 1 | -0.0361669 |
| OGA | O-GlcNAcase | -0.0358967 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0356301 |
| RBM39 | RNA binding motif protein 39 | -0.0354641 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0354617 |
| AHNAK | AHNAK nucleoprotein | -0.0353787 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0352797 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0347133 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0343628 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0343166 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0342007 |
| RTN4 | reticulon 4 | -0.0340132 |
| RPS5 | ribosomal protein S5 | -0.032888 |
| PDS5B | PDS5 cohesin associated factor B | -0.0328491 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0327454 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0322444 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0321487 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0311716 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.030897 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0301071 |
| THOC2 | THO complex 2 | -0.0300305 |
| RRBP1 | ribosome binding protein 1 | -0.0300098 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0294666 |
| SQSTM1 | sequestosome 1 | -0.0293448 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0291446 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0290707 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0290088 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0289413 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0286836 |
| XPO1 | exportin 1 | -0.0285702 |
| EPCAM | epithelial cell adhesion molecule | -0.028219 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0281117 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0280363 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.027448 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0270782 |
| JUP | junction plakoglobin | -0.0269656 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0266593 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0263929 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0260934 |
| HMGB1 | high mobility group box 1 | -0.0260173 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0259269 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0259155 |
| MATR3 | matrin 3 | -0.0258518 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0258003 |
| WASF2 | WAS protein family, member 2 | -0.0257773 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0257077 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0257004 |
| LMNA | lamin A/C | -0.0256029 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0255133 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0254947 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0254227 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0254076 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0252754 |
| GNAS | GNAS complex locus | -0.0250248 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0249617 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0248488 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0248011 |
| EMP1 | epithelial membrane protein 1 | -0.0247506 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0246929 |
| CENPF | centromere protein F, 350/400kDa | -0.0242125 |
| RNF43 | ring finger protein 43 | -0.0239626 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0238165 |
