| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tubulin inhibitor 6_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.629771 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.244254 |
| DSPP | dentin sialophosphoprotein | 0.138041 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.109264 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.106341 |
| ENO1 | enolase 1, (alpha) | 0.100921 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0935325 |
| SVIL | supervillin | 0.0910526 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0907868 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0885741 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0857047 |
| ASPH | aspartate beta-hydroxylase | 0.0819841 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0776672 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0719977 |
| SDC4 | syndecan 4 | 0.0682001 |
| ATXN1 | ataxin 1 | 0.0653045 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0579775 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0531685 |
| FAM107B | family with sequence similarity 107, member B | 0.0522947 |
| EHBP1 | EH domain binding protein 1 | 0.0516997 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0506107 |
| FN1 | fibronectin 1 | 0.050117 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0495042 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0470821 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0465368 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0462307 |
| FRMD5 | FERM domain containing 5 | 0.0455152 |
| FNDC3B | fibronectin type III domain containing 3B | 0.04466 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0434244 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0432203 |
| DTNA | dystrobrevin, alpha | 0.0427584 |
| PEG3 | paternally expressed 3 | 0.0425382 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0391131 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0383042 |
| TNS1 | tensin 1 | 0.0381213 |
| KIAA1217 | KIAA1217 | 0.0376244 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0372693 |
| ACTG1 | actin gamma 1 | 0.0359762 |
| KYNU | kynureninase | 0.0359098 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0359042 |
| DST | dystonin | 0.0356328 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0353073 |
| CP | ceruloplasmin (ferroxidase) | 0.0351832 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0344392 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0343119 |
| GPC6 | glypican 6 | 0.0343085 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0330917 |
| PLIN2 | perilipin 2 | 0.0326446 |
| KRT8 | keratin 8, type II | 0.0325689 |
| RNF213 | ring finger protein 213 | 0.0321727 |
| TF | transferrin | 0.0317709 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0317489 |
| PLXDC2 | plexin domain containing 2 | 0.0311675 |
| LDHA | lactate dehydrogenase A | 0.0301634 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0301025 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0298906 |
| FAM13A | family with sequence similarity 13, member A | 0.0294529 |
| FOXP1 | forkhead box P1 | 0.029425 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0292121 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0282685 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0281515 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0280569 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0280357 |
| INTS6 | integrator complex subunit 6 | 0.0275211 |
| NDRG1 | N-myc downstream regulated 1 | 0.027493 |
| CANX | calnexin | 0.0271733 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.027172 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0270995 |
| MYO6 | myosin VI | 0.0268963 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0267419 |
| INSIG2 | insulin induced gene 2 | 0.0266923 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0264851 |
| PRKCA | protein kinase C, alpha | 0.026259 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0260806 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0259901 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0257833 |
| FLNB | filamin B, beta | 0.0255819 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0254728 |
| CLIC4 | chloride intracellular channel 4 | 0.0254586 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0251579 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0249674 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0249181 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0248158 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0247889 |
| DIAPH1 | diaphanous-related formin 1 | 0.024777 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0246232 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0241317 |
| GOLGB1 | golgin B1 | 0.0239887 |
| GSE1 | Gse1 coiled-coil protein | 0.0239151 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0236503 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0236244 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0233701 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0231683 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0230442 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0229833 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0228346 |
| GK | glycerol kinase | 0.0226454 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0225159 |
| RNASET2 | ribonuclease T2 | 0.0224572 |
| TNS3 | tensin 3 | 0.02217 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.14547 |
| APOB | apolipoprotein B | -0.0866449 |
| MT2A | metallothionein 2A | -0.0859182 |
| GPC3 | glypican 3 | -0.0692357 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0676086 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.065736 |
| RPL37A | ribosomal protein L37a | -0.0649619 |
| RPS12 | ribosomal protein S12 | -0.0595518 |
| APOA2 | apolipoprotein A-II | -0.0544671 |
| SLC38A2 | solute carrier family 38, member 2 | -0.051403 |
| A2M | alpha-2-macroglobulin | -0.0470002 |
| TRIM26 | tripartite motif containing 26 | -0.0460968 |
| RPS6 | ribosomal protein S6 | -0.0432517 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0429821 |
| RPL11 | ribosomal protein L11 | -0.0417361 |
| RPS27A | ribosomal protein S27a | -0.0407164 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0386172 |
| RPLP1 | ribosomal protein, large, P1 | -0.0377374 |
| RPS3 | ribosomal protein S3 | -0.0376181 |
| RPS29 | ribosomal protein S29 | -0.0346187 |
| RPS8 | ribosomal protein S8 | -0.0341912 |
| RPL12 | ribosomal protein L12 | -0.03412 |
| RPS19 | ribosomal protein S19 | -0.0337971 |
| RPS23 | ribosomal protein S23 | -0.0331306 |
| RPS24 | ribosomal protein S24 | -0.0329609 |
| RPL26 | ribosomal protein L26 | -0.0323458 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0317635 |
| RPL36 | ribosomal protein L36 | -0.0310006 |
| PTCHD4 | patched domain containing 4 | -0.0305273 |
| RPL35A | ribosomal protein L35a | -0.0296985 |
| RRBP1 | ribosome binding protein 1 | -0.0289706 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0288223 |
| RPLP2 | ribosomal protein, large, P2 | -0.0275449 |
| RPS13 | ribosomal protein S13 | -0.0267179 |
| RPS25 | ribosomal protein S25 | -0.0266125 |
| RPL9 | ribosomal protein L9 | -0.0258357 |
| FTL | ferritin, light polypeptide | -0.0248081 |
| RBM25 | RNA binding motif protein 25 | -0.0239974 |
| CFB | complement factor B | -0.0237058 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0230454 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0223812 |
| LYZ | lysozyme | -0.0218948 |
| RPL28 | ribosomal protein L28 | -0.0218384 |
| RPL31 | ribosomal protein L31 | -0.0217805 |
| RPS11 | ribosomal protein S11 | -0.0214367 |
| VCL | vinculin | -0.0214018 |
| RPL32 | ribosomal protein L32 | -0.0213969 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0212214 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0210791 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0210407 |
| EGR1 | early growth response 1 | -0.0208311 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0199718 |
| RPL38 | ribosomal protein L38 | -0.0199037 |
| BCL2L1 | BCL2-like 1 | -0.0198894 |
| RPL13A | ribosomal protein L13a | -0.0197685 |
| MALT1 | MALT1 paracaspase | -0.0196717 |
| RPS14 | ribosomal protein S14 | -0.0192541 |
| RPS20 | ribosomal protein S20 | -0.0190192 |
| RPL34 | ribosomal protein L34 | -0.0187919 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.0187818 |
| APOE | apolipoprotein E | -0.0186065 |
| APOC1 | apolipoprotein C-I | -0.0185316 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0184475 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0182274 |
| IER3 | immediate early response 3 | -0.01783 |
| GNAS | GNAS complex locus | -0.017558 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0174133 |
| ZNF644 | zinc finger protein 644 | -0.0173316 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0170751 |
| RPS10 | ribosomal protein S10 | -0.0170365 |
| PTMA | prothymosin, alpha | -0.0165634 |
| POU2F1 | POU class 2 homeobox 1 | -0.0164543 |
| ACTN4 | actinin, alpha 4 | -0.0159149 |
| RPL7A | ribosomal protein L7a | -0.0156028 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0155778 |
| RPL8 | ribosomal protein L8 | -0.015545 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0154465 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0147488 |
| SYNJ2 | synaptojanin 2 | -0.0147162 |
| RACK1 | receptor for activated C kinase 1 | -0.0145148 |
| SELENOP | selenoprotein P | -0.0144659 |
| RPL30 | ribosomal protein L30 | -0.014234 |
| NFIA | nuclear factor I/A | -0.0140318 |
| RPS15 | ribosomal protein S15 | -0.0140203 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.01398 |
| RPS27 | ribosomal protein S27 | -0.0138054 |
| YBX1 | Y box binding protein 1 | -0.0137983 |
| RPL37 | ribosomal protein L37 | -0.0137458 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.013715 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.0136966 |
| NPR2 | natriuretic peptide receptor 2 | -0.0136889 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0136286 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0135781 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0135138 |
| RPL5 | ribosomal protein L5 | -0.0134902 |
| RPL27A | ribosomal protein L27a | -0.0131936 |
| CST3 | cystatin C | -0.0131525 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0131524 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0130962 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0130489 |
