| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.123741 |
| ACTG1 | actin gamma 1 | 0.106408 |
| INTS6 | integrator complex subunit 6 | 0.0996866 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0995865 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0985049 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0975116 |
| EXT1 | exostosin glycosyltransferase 1 | 0.096342 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0949672 |
| TLE4 | transducin-like enhancer of split 4 | 0.0881741 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0843384 |
| POTEF | POTE ankyrin domain family, member F | 0.0739027 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0717436 |
| SDC4 | syndecan 4 | 0.0714337 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0713977 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0705432 |
| ENO1 | enolase 1, (alpha) | 0.0695102 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0689803 |
| NAV2 | neuron navigator 2 | 0.0649339 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0640703 |
| ASPH | aspartate beta-hydroxylase | 0.0630723 |
| ZNF841 | zinc finger protein 841 | 0.061868 |
| ERBIN | erbb2 interacting protein | 0.0618654 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0613419 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0600984 |
| TPM3 | tropomyosin 3 | 0.0600917 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0589008 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.05848 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0583434 |
| LDHA | lactate dehydrogenase A | 0.0544577 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0529413 |
| PCBP2 | poly(rC) binding protein 2 | 0.0524784 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.052448 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0518256 |
| DST | dystonin | 0.0502765 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0486604 |
| SET | SET nuclear proto-oncogene | 0.0474391 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0466879 |
| STC2 | stanniocalcin 2 | 0.0458351 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0446347 |
| CANX | calnexin | 0.0442162 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0423399 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0416459 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.041014 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0405672 |
| SMAD3 | SMAD family member 3 | 0.040085 |
| FNIP1 | folliculin interacting protein 1 | 0.0400235 |
| KRT8 | keratin 8, type II | 0.0399227 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0388162 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0382777 |
| VCL | vinculin | 0.0378232 |
| UBAP2 | ubiquitin associated protein 2 | 0.0377448 |
| SQSTM1 | sequestosome 1 | 0.037583 |
| HLA-C | major histocompatibility complex, class I, C | 0.0375627 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0361289 |
| CLIC4 | chloride intracellular channel 4 | 0.0360707 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0359986 |
| RUNX1 | runt-related transcription factor 1 | 0.0359316 |
| KLF12 | Kruppel-like factor 12 | 0.0358205 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0353156 |
| RND3 | Rho family GTPase 3 | 0.0350971 |
| TUFT1 | tuftelin 1 | 0.0349887 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0346923 |
| ATXN1 | ataxin 1 | 0.0344916 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0344129 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0335438 |
| SEPTIN9 | septin 9 | 0.0335265 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0332718 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0332051 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0327408 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0325061 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0324854 |
| ZNF432 | zinc finger protein 432 | 0.0323567 |
| MT2A | metallothionein 2A | 0.0323152 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0319824 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0311298 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0307916 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0307588 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0300224 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0297134 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0297045 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0294003 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.029224 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0291987 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0289809 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0288765 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0286681 |
| SMYD3 | SET and MYND domain containing 3 | 0.0279606 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0275405 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0272756 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0271889 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.027151 |
| RPS3 | ribosomal protein S3 | 0.0270523 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0268887 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.02669 |
| CALD1 | caldesmon 1 | 0.0265856 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0265016 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0264851 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0264517 |
| LIMA1 | LIM domain and actin binding 1 | 0.0264388 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0264115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.17956 |
| FTL | ferritin, light polypeptide | -0.167483 |
| NDRG1 | N-myc downstream regulated 1 | -0.108532 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.106082 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.105889 |
| HLA-B | major histocompatibility complex, class I, B | -0.100318 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0880042 |
| TMSB10 | thymosin beta 10 | -0.0713582 |
| PLCB4 | phospholipase C, beta 4 | -0.0672532 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0503096 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0481947 |
| TXNRD1 | thioredoxin reductase 1 | -0.0465037 |
| OSMR | oncostatin M receptor | -0.0444567 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0438134 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0430935 |
| VIM | vimentin | -0.0414003 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0374983 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0369016 |
| POSTN | periostin, osteoblast specific factor | -0.0361709 |
| ARF4 | ADP-ribosylation factor 4 | -0.0346152 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0342625 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0341994 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0321413 |
| S100A10 | S100 calcium binding protein A10 | -0.0316755 |
| CCDC80 | coiled-coil domain containing 80 | -0.0316385 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0315854 |
| PFN1 | profilin 1 | -0.0310166 |
| AFAP1 | actin filament associated protein 1 | -0.0305046 |
| PKM | pyruvate kinase, muscle | -0.0300552 |
| SULF1 | sulfatase 1 | -0.0300088 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0296661 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0274963 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0273607 |
| TUBB | tubulin, beta class I | -0.0273384 |
| CCND1 | cyclin D1 | -0.0271684 |
| H1-4 | H1.4 linker histone, cluster member | -0.0269414 |
| PTMA | prothymosin, alpha | -0.0265741 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0265564 |
| TPX2 | TPX2, microtubule-associated | -0.0263208 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0262063 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0260388 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0257107 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.025411 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.025248 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0250832 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0248489 |
| MKI67 | marker of proliferation Ki-67 | -0.0240984 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.023967 |
| TPM1 | tropomyosin 1 (alpha) | -0.0238762 |
| GLIS3 | GLIS family zinc finger 3 | -0.0237819 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.023555 |
| NOP58 | NOP58 ribonucleoprotein | -0.0233493 |
| GOLT1B | golgi transport 1B | -0.023317 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0232465 |
| PGK1 | phosphoglycerate kinase 1 | -0.0230923 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0229675 |
| RRBP1 | ribosome binding protein 1 | -0.022914 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0226382 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0224174 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0223169 |
| CTSD | cathepsin D | -0.0212995 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0206232 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0205956 |
| TPI1 | triosephosphate isomerase 1 | -0.0205955 |
| TFG | TRK-fused gene | -0.0200623 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0196901 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.019055 |
| GOLGA4 | golgin A4 | -0.0186741 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.018611 |
| SCFD2 | sec1 family domain containing 2 | -0.0185222 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0184731 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0181339 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0179201 |
| IKBIP | IKBKB interacting protein | -0.0176291 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0174965 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.017269 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0172596 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0171401 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0170904 |
| TAGLN2 | transgelin 2 | -0.017056 |
| THOC2 | THO complex 2 | -0.0169994 |
| TRIM56 | tripartite motif containing 56 | -0.016995 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0169134 |
| TMEM41B | transmembrane protein 41B | -0.0167904 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0167092 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0166924 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | -0.0166308 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0165634 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0161746 |
| SBF2 | SET binding factor 2 | -0.0160646 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0159632 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0158965 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0156906 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0156088 |
| NOL7 | nucleolar protein 7, 27kDa | -0.0155677 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0155667 |
| SMAD5 | SMAD family member 5 | -0.0154997 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0154827 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0153841 |
| TNPO1 | transportin 1 | -0.0153474 |
