| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tubulin inhibitor 6_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0810196 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0681097 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0595652 |
| RBM39 | RNA binding motif protein 39 | 0.056187 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0548251 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0529444 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0522393 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0517057 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0510388 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0493104 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0454818 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0443338 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0437874 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0424601 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0412951 |
| APP | amyloid beta (A4) precursor protein | 0.0411589 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0403617 |
| TPM3 | tropomyosin 3 | 0.0401596 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0397143 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0395192 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0392826 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.038037 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0374516 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0372594 |
| COPA | coatomer protein complex, subunit alpha | 0.036915 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0366047 |
| CCNL1 | cyclin L1 | 0.0360927 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0358038 |
| WDR43 | WD repeat domain 43 | 0.0357572 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0349363 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0346068 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0344942 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0342734 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0340417 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0339457 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0330664 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0327142 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0321573 |
| ERBIN | erbb2 interacting protein | 0.0318348 |
| CYTH1 | cytohesin 1 | 0.0317684 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0314457 |
| NCKAP1 | NCK-associated protein 1 | 0.0313829 |
| PCBP2 | poly(rC) binding protein 2 | 0.031153 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0302234 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0301562 |
| MYOF | myoferlin | 0.0299871 |
| CUL3 | cullin 3 | 0.0299715 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0297388 |
| RUNX1 | runt-related transcription factor 1 | 0.0297288 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0295586 |
| ACTG1 | actin gamma 1 | 0.0294824 |
| PTK2 | protein tyrosine kinase 2 | 0.0294289 |
| RBM25 | RNA binding motif protein 25 | 0.0289138 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0288538 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.0287161 |
| FMNL2 | formin-like 2 | 0.0283499 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0279474 |
| RPS12 | ribosomal protein S12 | 0.0278801 |
| PARD3 | par-3 family cell polarity regulator | 0.02786 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.027835 |
| HSPA8 | heat shock 70kDa protein 8 | 0.027748 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0277315 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0276015 |
| YTHDC1 | YTH domain containing 1 | 0.0268106 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.02681 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0266896 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0260728 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0259231 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0256955 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0256825 |
| KYNU | kynureninase | 0.0252922 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.025197 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0250804 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0248984 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0248064 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0246203 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0245494 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0245249 |
| AHNAK | AHNAK nucleoprotein | 0.0244826 |
| UBAP2L | ubiquitin associated protein 2-like | 0.024121 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.024061 |
| USP37 | ubiquitin specific peptidase 37 | 0.0238913 |
| RBM33 | RNA binding motif protein 33 | 0.0238413 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.023684 |
| SDC4 | syndecan 4 | 0.0235133 |
| ZNF207 | zinc finger protein 207 | 0.0231607 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0230286 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.02297 |
| FOXO3 | forkhead box O3 | 0.0228917 |
| SIK3 | SIK family kinase 3 | 0.0226373 |
| SPAG9 | sperm associated antigen 9 | 0.022515 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0224678 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0224089 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0221211 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0218633 |
| CCNY | cyclin Y | 0.021736 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0216407 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0211881 |
| RCOR1 | REST corepressor 1 | 0.0209891 |
| RAB10 | RAB10, member RAS oncogene family | 0.0209791 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.240843 |
| TMSB10 | thymosin beta 10 | -0.174586 |
| VIM | vimentin | -0.168988 |
| FTL | ferritin, light polypeptide | -0.113007 |
| MT2A | metallothionein 2A | -0.0968177 |
| IGF2 | insulin-like growth factor 2 | -0.0885712 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0693862 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0623343 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0615276 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0615073 |
| EGR1 | early growth response 1 | -0.0605414 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0559016 |
| GRAMD1B | GRAM domain containing 1B | -0.051684 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0507531 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0492274 |
| PKM | pyruvate kinase, muscle | -0.048821 |
| PYGL | phosphorylase, glycogen, liver | -0.0477704 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0440942 |
| S100A10 | S100 calcium binding protein A10 | -0.0399067 |
| MCL1 | myeloid cell leukemia 1 | -0.0387998 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0381408 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0372159 |
| PFN1 | profilin 1 | -0.0359202 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.034404 |
| HMGA1 | high mobility group AT-hook 1 | -0.0341476 |
| PTMA | prothymosin, alpha | -0.0330901 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0326313 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0319675 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0319507 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0300788 |
| TPM4 | tropomyosin 4 | -0.03005 |
| SRGN | serglycin | -0.0281849 |
| S100A6 | S100 calcium binding protein A6 | -0.0270584 |
| STC1 | stanniocalcin 1 | -0.0268009 |
| RPS21 | ribosomal protein S21 | -0.0261471 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0261429 |
| RAD51B | RAD51 paralog B | -0.0260309 |
| S100A11 | S100 calcium binding protein A11 | -0.0253197 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0243274 |
| IER3 | immediate early response 3 | -0.024275 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0237205 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0224464 |
| TAGLN2 | transgelin 2 | -0.0224057 |
| OSMR | oncostatin M receptor | -0.0223543 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0221143 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.022084 |
| PRDX1 | peroxiredoxin 1 | -0.0219869 |
| RPLP1 | ribosomal protein, large, P1 | -0.0217717 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0215597 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0214919 |
| RPL19 | ribosomal protein L19 | -0.0211234 |
| ANGPTL4 | angiopoietin-like 4 | -0.0205944 |
| TUBB | tubulin, beta class I | -0.0205518 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0204312 |
| RPL31 | ribosomal protein L31 | -0.020393 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0198657 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0195868 |
| MKI67 | marker of proliferation Ki-67 | -0.0194786 |
| TPI1 | triosephosphate isomerase 1 | -0.0194215 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0192387 |
| RPS24 | ribosomal protein S24 | -0.0190147 |
| POTEF | POTE ankyrin domain family, member F | -0.0190127 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0189114 |
| EFNA5 | ephrin-A5 | -0.0188426 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0184462 |
| RPS23 | ribosomal protein S23 | -0.0183574 |
| RPS5 | ribosomal protein S5 | -0.0182862 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0181865 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0181183 |
| MAP1B | microtubule-associated protein 1B | -0.0180655 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0178012 |
| LDHA | lactate dehydrogenase A | -0.0176151 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0173474 |
| FGB | fibrinogen beta chain | -0.0173241 |
| RPL35A | ribosomal protein L35a | -0.0168408 |
| RPL23 | ribosomal protein L23 | -0.0168171 |
| RPL8 | ribosomal protein L8 | -0.016743 |
| LMNA | lamin A/C | -0.0167112 |
| NNMT | nicotinamide N-methyltransferase | -0.0166648 |
| S100A9 | S100 calcium binding protein A9 | -0.0163219 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0163172 |
| RPS19 | ribosomal protein S19 | -0.0162563 |
| RPL36AL | ribosomal protein L36a-like | -0.0161907 |
| ASTN2 | astrotactin 2 | -0.0161424 |
| NEBL | nebulette | -0.015958 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0158612 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0158595 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0158367 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.01573 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0155095 |
| RPS15 | ribosomal protein S15 | -0.0153852 |
| LAMB1 | laminin, beta 1 | -0.0153534 |
| ENO1 | enolase 1, (alpha) | -0.0152324 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | -0.0151619 |
| RPL11 | ribosomal protein L11 | -0.0150656 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0150124 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0148981 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0147205 |
| RPL32 | ribosomal protein L32 | -0.014659 |
| RPS11 | ribosomal protein S11 | -0.0146198 |
