| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.298971 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.165118 |
| EXT1 | exostosin glycosyltransferase 1 | 0.159697 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.119336 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.11855 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.116891 |
| POTEF | POTE ankyrin domain family, member F | 0.109223 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0979627 |
| AHNAK | AHNAK nucleoprotein | 0.0949319 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0896763 |
| SDC4 | syndecan 4 | 0.0828448 |
| ERBIN | erbb2 interacting protein | 0.0798365 |
| EFNA5 | ephrin-A5 | 0.0721098 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0695323 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0675925 |
| DSPP | dentin sialophosphoprotein | 0.0632846 |
| FBXO32 | F-box protein 32 | 0.0631915 |
| NAV2 | neuron navigator 2 | 0.0621902 |
| FNIP1 | folliculin interacting protein 1 | 0.0607581 |
| VCL | vinculin | 0.0604753 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0595167 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0575367 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.056626 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0550294 |
| GOLGB1 | golgin B1 | 0.0548869 |
| MYO1E | myosin IE | 0.054614 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0544153 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0534105 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0532573 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0528114 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0517929 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0516358 |
| CANX | calnexin | 0.0511498 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.050026 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0492903 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0492182 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0486292 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0485189 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0483009 |
| KRT8 | keratin 8, type II | 0.0474777 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0469362 |
| CTBP2 | C-terminal binding protein 2 | 0.046455 |
| LAMB3 | laminin, beta 3 | 0.0460208 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.045189 |
| CD109 | CD109 molecule | 0.0448217 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0445954 |
| LMO7 | LIM domain 7 | 0.0443882 |
| DTNA | dystrobrevin, alpha | 0.0437075 |
| RCOR1 | REST corepressor 1 | 0.0433811 |
| ENO1 | enolase 1, (alpha) | 0.0430365 |
| RAB7A | RAB7A, member RAS oncogene family | 0.042941 |
| PALLD | palladin, cytoskeletal associated protein | 0.0424835 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0421345 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.042045 |
| ATXN1 | ataxin 1 | 0.0419006 |
| TJP1 | tight junction protein 1 | 0.0414401 |
| MYO6 | myosin VI | 0.0409474 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0406886 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.040225 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.039915 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0397857 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0397726 |
| TPM3 | tropomyosin 3 | 0.0397685 |
| RAI14 | retinoic acid induced 14 | 0.039578 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0393791 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0389718 |
| RNF213 | ring finger protein 213 | 0.0384039 |
| MYOF | myoferlin | 0.038149 |
| ETV6 | ets variant 6 | 0.0371828 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0371702 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0368122 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0367238 |
| VGLL3 | vestigial-like family member 3 | 0.0366635 |
| SMAD3 | SMAD family member 3 | 0.0366563 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0363468 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0363298 |
| DUSP10 | dual specificity phosphatase 10 | 0.0362638 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0362338 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0361828 |
| RUNX1 | runt-related transcription factor 1 | 0.0361315 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0360837 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0360287 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0360197 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0357199 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0356452 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0355626 |
| RAB10 | RAB10, member RAS oncogene family | 0.0355061 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0353609 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0352751 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0351916 |
| CDK13 | cyclin-dependent kinase 13 | 0.0350251 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0350157 |
| PLEC | plectin | 0.0345527 |
| MAP1B | microtubule-associated protein 1B | 0.0341722 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0337611 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.033743 |
| ARRDC3 | arrestin domain containing 3 | 0.0334924 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0330924 |
| OCLN | occludin | 0.032968 |
| PTK2 | protein tyrosine kinase 2 | 0.0328591 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.190179 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1322 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.129246 |
| FTL | ferritin, light polypeptide | -0.126918 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.100126 |
| HMGA1 | high mobility group AT-hook 1 | -0.0775962 |
| TMSB10 | thymosin beta 10 | -0.0707963 |
| FN1 | fibronectin 1 | -0.069318 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0614838 |
| TFG | TRK-fused gene | -0.0543596 |
| S100A10 | S100 calcium binding protein A10 | -0.0504805 |
| FAM162A | family with sequence similarity 162, member A | -0.0470197 |
| RNF145 | ring finger protein 145 | -0.0466988 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0449204 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0447705 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0408587 |
| RPL32 | ribosomal protein L32 | -0.0401135 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0398433 |
| S100A6 | S100 calcium binding protein A6 | -0.0391269 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0388913 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0352404 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0340481 |
| PTMA | prothymosin, alpha | -0.0331571 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0322816 |
| RPS23 | ribosomal protein S23 | -0.0321145 |
| RPS6 | ribosomal protein S6 | -0.0316189 |
| RPL8 | ribosomal protein L8 | -0.0297644 |
| RYBP | RING1 and YY1 binding protein | -0.0296489 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.029606 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0284725 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0280901 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0275853 |
| PGK1 | phosphoglycerate kinase 1 | -0.0273037 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0271022 |
| MATR3 | matrin 3 | -0.0267022 |
| NUP58 | nucleoporin 58 | -0.0266947 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0266686 |
| SLC38A1 | solute carrier family 38, member 1 | -0.026615 |
| RPS2 | ribosomal protein S2 | -0.0264055 |
| RIOK3 | RIO kinase 3 | -0.0257788 |
| G0S2 | G0/G1 switch 2 | -0.0253457 |
| MT2A | metallothionein 2A | -0.0252975 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0248425 |
| TXNRD1 | thioredoxin reductase 1 | -0.0247979 |
| EPCAM | epithelial cell adhesion molecule | -0.0247301 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0245188 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0244365 |
| USP3 | ubiquitin specific peptidase 3 | -0.0241499 |
| FOSL1 | FOS-like antigen 1 | -0.0238946 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0230683 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0226471 |
| CHMP2B | charged multivesicular body protein 2B | -0.0217733 |
| PAPOLA | poly(A) polymerase alpha | -0.0217169 |
| UPP1 | uridine phosphorylase 1 | -0.0216436 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0216422 |
| RPS5 | ribosomal protein S5 | -0.0214832 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0214533 |
| RPS19 | ribosomal protein S19 | -0.0213096 |
| RPL6 | ribosomal protein L6 | -0.0212077 |
| ANXA5 | annexin A5 | -0.0212053 |
| RPLP1 | ribosomal protein, large, P1 | -0.0211535 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0210983 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0210678 |
| TMEM123 | transmembrane protein 123 | -0.0209676 |
| TKT | transketolase | -0.0208949 |
| AREG | amphiregulin | -0.0203237 |
| DSTN | destrin (actin depolymerizing factor) | -0.0203169 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0202552 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0200652 |
| CLINT1 | clathrin interactor 1 | -0.0197057 |
| TRAM1 | translocation associated membrane protein 1 | -0.0197042 |
| ZNF292 | zinc finger protein 292 | -0.0196779 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0196189 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0195254 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0193462 |
| RPL12 | ribosomal protein L12 | -0.0193354 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0192524 |
| MXD1 | MAX dimerization protein 1 | -0.0190951 |
| CDK17 | cyclin-dependent kinase 17 | -0.0189592 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0188772 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0186642 |
| RPL11 | ribosomal protein L11 | -0.0186528 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.01862 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0183699 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0180801 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0180165 |
| FAM3C | family with sequence similarity 3, member C | -0.017989 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0177901 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0177224 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0176917 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | -0.01769 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0176834 |
| TAGLN2 | transgelin 2 | -0.0176138 |
| YBX3 | Y box binding protein 3 | -0.0174392 |
| UBC | ubiquitin C | -0.0171501 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0169526 |
| RPL28 | ribosomal protein L28 | -0.0169105 |
| RPL34 | ribosomal protein L34 | -0.0168747 |
| CD83 | CD83 molecule | -0.0168314 |
| RLF | rearranged L-myc fusion | -0.0168063 |
