| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDLIM5 | PDZ and LIM domain 5 | 0.100646 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0891121 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0793081 |
| DST | dystonin | 0.0763693 |
| KYNU | kynureninase | 0.0676419 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0627977 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0561808 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0525677 |
| ACTG1 | actin gamma 1 | 0.0488751 |
| CD109 | CD109 molecule | 0.0477165 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0467789 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0461203 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0452966 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0449517 |
| SMAD2 | SMAD family member 2 | 0.0418996 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0413022 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0396324 |
| STC2 | stanniocalcin 2 | 0.038851 |
| FMNL2 | formin-like 2 | 0.038779 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0372939 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0354799 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0349738 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0346021 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0330259 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0328015 |
| MAP7 | microtubule-associated protein 7 | 0.0302063 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0296459 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0292938 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0292692 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0290576 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.028421 |
| GDA | guanine deaminase | 0.0283344 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0276276 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0272802 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0272239 |
| FNIP1 | folliculin interacting protein 1 | 0.0264028 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0256692 |
| MYOF | myoferlin | 0.0236515 |
| INTS6 | integrator complex subunit 6 | 0.0236237 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0235211 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0225186 |
| ATXN1 | ataxin 1 | 0.0224514 |
| TPM3 | tropomyosin 3 | 0.0222404 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0217496 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0214746 |
| NRG1 | neuregulin 1 | 0.0213881 |
| SQSTM1 | sequestosome 1 | 0.0213452 |
| RASAL2 | RAS protein activator like 2 | 0.0212046 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0209833 |
| BMP6 | bone morphogenetic protein 6 | 0.0209359 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0208206 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0207937 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0207854 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0207517 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0206311 |
| MB21D2 | Mab-21 domain containing 2 | 0.0206131 |
| RUNX1 | runt-related transcription factor 1 | 0.0200877 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0197461 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0196503 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0195975 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.0185883 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0185149 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0182607 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0182567 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0181638 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0177915 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0174569 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0173954 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.0173355 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0172065 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0171407 |
| DNER | delta/notch-like EGF repeat containing | 0.0170981 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.0169901 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0169428 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.016899 |
| TBXT | T-box transcription factor T | 0.0168736 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0168624 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0168078 |
| LDHA | lactate dehydrogenase A | 0.0167351 |
| TENM2 | teneurin transmembrane protein 2 | 0.0164076 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0161348 |
| MYO10 | myosin X | 0.0161346 |
| ARRDC3 | arrestin domain containing 3 | 0.0159462 |
| NTN4 | netrin 4 | 0.0159383 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0158754 |
| PCBP2 | poly(rC) binding protein 2 | 0.0158334 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0156934 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0156124 |
| SEPTIN9 | septin 9 | 0.0156038 |
| SCFD1 | sec1 family domain containing 1 | 0.0155557 |
| CUX1 | cut-like homeobox 1 | 0.0153836 |
| COPA | coatomer protein complex, subunit alpha | 0.0153004 |
| EZR | ezrin | 0.015027 |
| GOLGB1 | golgin B1 | 0.0149026 |
| ALPK2 | alpha-kinase 2 | 0.0148265 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0147531 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0144904 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0144725 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0144041 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0143878 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.215817 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164224 |
| FN1 | fibronectin 1 | -0.160145 |
| TMSB10 | thymosin beta 10 | -0.150874 |
| VIM | vimentin | -0.115439 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0922573 |
| RPS27A | ribosomal protein S27a | -0.0803499 |
| UBC | ubiquitin C | -0.0787793 |
| RPS24 | ribosomal protein S24 | -0.0729753 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.065397 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0644919 |
| PTMA | prothymosin, alpha | -0.0635886 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0632822 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0587216 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0575023 |
| FTL | ferritin, light polypeptide | -0.053757 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0537478 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0461609 |
| TXNRD1 | thioredoxin reductase 1 | -0.0450479 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0426992 |
| EFNA5 | ephrin-A5 | -0.0423576 |
| SMYD3 | SET and MYND domain containing 3 | -0.041432 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0408399 |
| RPS23 | ribosomal protein S23 | -0.0406919 |
| NRCAM | neuronal cell adhesion molecule | -0.0383252 |
| RPLP1 | ribosomal protein, large, P1 | -0.0377693 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.037707 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0371223 |
| SRGN | serglycin | -0.0365407 |
| GRAMD1B | GRAM domain containing 1B | -0.0365375 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0363404 |
| RPL31 | ribosomal protein L31 | -0.0363009 |
| RPL37A | ribosomal protein L37a | -0.0360366 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.035836 |
| RPL12 | ribosomal protein L12 | -0.0356035 |
| RPL23 | ribosomal protein L23 | -0.035258 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0344124 |
| GNAS | GNAS complex locus | -0.0335561 |
| ASPH | aspartate beta-hydroxylase | -0.0334619 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0323802 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0316449 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0314276 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0309262 |
| RPLP2 | ribosomal protein, large, P2 | -0.0309051 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0304943 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0301846 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0290456 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0284729 |
| MCL1 | myeloid cell leukemia 1 | -0.0283236 |
| NCKAP5 | NCK-associated protein 5 | -0.0280806 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0280321 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0278389 |
| S100A10 | S100 calcium binding protein A10 | -0.0277525 |
| PTGR1 | prostaglandin reductase 1 | -0.0276034 |
| OSMR | oncostatin M receptor | -0.0274948 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0272779 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0272359 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0265687 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0265432 |
| RPS29 | ribosomal protein S29 | -0.0258794 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0253104 |
| RPL38 | ribosomal protein L38 | -0.024741 |
| RPL26 | ribosomal protein L26 | -0.0243512 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0237407 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.023679 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0235571 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0235483 |
| RPL34 | ribosomal protein L34 | -0.0233866 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0230604 |
| RPL9 | ribosomal protein L9 | -0.0224508 |
| PKM | pyruvate kinase, muscle | -0.0224475 |
| PCBP3 | poly(rC) binding protein 3 | -0.0222896 |
| RPS16 | ribosomal protein S16 | -0.0222432 |
| RPS25 | ribosomal protein S25 | -0.0222296 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0218521 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0214643 |
| RPS21 | ribosomal protein S21 | -0.020967 |
| RPL32 | ribosomal protein L32 | -0.0208864 |
| PRDX1 | peroxiredoxin 1 | -0.0208729 |
| RPL28 | ribosomal protein L28 | -0.0208654 |
| MFF | mitochondrial fission factor | -0.0207623 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0207099 |
| CADM2 | cell adhesion molecule 2 | -0.0206478 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0203418 |
| RPS15 | ribosomal protein S15 | -0.0202425 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0198995 |
| RBM39 | RNA binding motif protein 39 | -0.0196545 |
| RPS5 | ribosomal protein S5 | -0.0196111 |
| PRSS23 | protease, serine, 23 | -0.0195793 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0194461 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0192526 |
| SRPK2 | SRSF protein kinase 2 | -0.0191423 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0191413 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0190545 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0190147 |
| RTN4 | reticulon 4 | -0.0189614 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0183024 |
| LAMB1 | laminin, beta 1 | -0.0181433 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0180558 |
| RPL13A | ribosomal protein L13a | -0.0180439 |
