| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
87 genes differentially expressed following the Tubulin inhibitor 6_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.200369 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.152331 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.151799 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.131768 |
| DSCAM | Down syndrome cell adhesion molecule | 0.118958 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.109286 |
| LMO7 | LIM domain 7 | 0.106368 |
| ACTG1 | actin gamma 1 | 0.0947719 |
| KRT18 | keratin 18, type I | 0.0898665 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0809052 |
| MYO1E | myosin IE | 0.0797332 |
| AHNAK | AHNAK nucleoprotein | 0.0693661 |
| FN1 | fibronectin 1 | 0.0664529 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0562926 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0562518 |
| RPS3 | ribosomal protein S3 | 0.0561683 |
| IGF2 | insulin-like growth factor 2 | 0.0548597 |
| SQSTM1 | sequestosome 1 | 0.0534733 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.048421 |
| RPS6 | ribosomal protein S6 | 0.0484104 |
| PTMA | prothymosin, alpha | 0.0476202 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.046972 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0463517 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0460187 |
| PTK2 | protein tyrosine kinase 2 | 0.0456889 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0445991 |
| RPL35A | ribosomal protein L35a | 0.0413787 |
| SLTM | SAFB-like, transcription modulator | 0.0393826 |
| USP34 | ubiquitin specific peptidase 34 | 0.0339567 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0337182 |
| CD44 | CD44 molecule (Indian blood group) | 0.025044 |
| FTL | ferritin, light polypeptide | 0.0248021 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0246371 |
| LDHA | lactate dehydrogenase A | 0.0239999 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0204104 |
| SLC38A1 | solute carrier family 38, member 1 | 0.020272 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0189437 |
| MYO10 | myosin X | 0.018938 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0181711 |
| ASPH | aspartate beta-hydroxylase | 0.0160718 |
| RPS8 | ribosomal protein S8 | 0.0157121 |
| SBF2 | SET binding factor 2 | 0.0125511 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00693338 |
| RPS12 | ribosomal protein S12 | 0.00518342 |
| INHBA | inhibin, beta A | 0.00504273 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 1.59683E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | -0.191566 |
| PDE10A | phosphodiesterase 10A | -0.187742 |
| EXT1 | exostosin glycosyltransferase 1 | -0.168925 |
| CDH13 | cadherin 13 | -0.125035 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.116536 |
| EFNA5 | ephrin-A5 | -0.100866 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0970682 |
| STC1 | stanniocalcin 1 | -0.0937289 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.083126 |
| HMGA2 | high mobility group AT-hook 2 | -0.0801658 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.057467 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0544755 |
| VCL | vinculin | -0.0444755 |
| RPS19 | ribosomal protein S19 | -0.0397607 |
| RPL23 | ribosomal protein L23 | -0.0396253 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0391219 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0338247 |
| MT2A | metallothionein 2A | -0.0334123 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0292763 |
| RBM39 | RNA binding motif protein 39 | -0.0273849 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0236936 |
| MYO6 | myosin VI | -0.0215237 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0205728 |
| TPM4 | tropomyosin 4 | -0.016963 |
| PRKCA | protein kinase C, alpha | -0.0133235 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0124085 |
| ENO1 | enolase 1, (alpha) | -0.0114731 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0110967 |
| RAI14 | retinoic acid induced 14 | -0.0107375 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00992572 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00954178 |
| TMSB10 | thymosin beta 10 | -0.00786263 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00711388 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.00628904 |
| FLNB | filamin B, beta | -0.00602204 |
| TPM3 | tropomyosin 3 | -0.00375182 |
| NDRG1 | N-myc downstream regulated 1 | -0.00366738 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00249277 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.00228246 |
| VIM | vimentin | -5.52852E-4 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -1.27585E-4 |
