| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tubulin inhibitor 6_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.149829 |
| COL3A1 | collagen, type III, alpha 1 | 0.128148 |
| ANKRD33B | ankyrin repeat domain 33B | 0.11348 |
| PEG10 | paternally expressed 10 | 0.110934 |
| COL5A2 | collagen, type V, alpha 2 | 0.104019 |
| HDAC9 | histone deacetylase 9 | 0.0971006 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0843432 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0839257 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0834361 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0798529 |
| FOXP2 | forkhead box P2 | 0.0789142 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0787732 |
| JMJD1C | jumonji domain containing 1C | 0.0765798 |
| APP | amyloid beta (A4) precursor protein | 0.071432 |
| ITGAV | integrin, alpha V | 0.0684757 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0683255 |
| ACTG1 | actin gamma 1 | 0.0671481 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0662917 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.064273 |
| PRTG | protogenin | 0.0637376 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0614029 |
| PCBP2 | poly(rC) binding protein 2 | 0.0605636 |
| PCDH18 | protocadherin 18 | 0.0587467 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.058495 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0578343 |
| MEIS2 | Meis homeobox 2 | 0.0572491 |
| CDC14A | cell division cycle 14A | 0.0571522 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0561046 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0557062 |
| POTEF | POTE ankyrin domain family, member F | 0.0547897 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.054617 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0545223 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0541793 |
| XPO1 | exportin 1 | 0.053932 |
| SRPK2 | SRSF protein kinase 2 | 0.0528446 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0515111 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0511788 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0500777 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0491795 |
| ZNF608 | zinc finger protein 608 | 0.0480287 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0479479 |
| CALR | calreticulin | 0.0474016 |
| DST | dystonin | 0.0470702 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0461415 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0456374 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0455168 |
| TMSB4X | thymosin beta 4, X-linked | 0.0454935 |
| B2M | beta-2-microglobulin | 0.0453343 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0444202 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0443509 |
| COL1A2 | collagen, type I, alpha 2 | 0.0424336 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0423694 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0419231 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0414678 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.039405 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0387346 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0382396 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0382218 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0379402 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0378878 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0375786 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0375346 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0373508 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0369139 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0368562 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.036813 |
| PRKD1 | protein kinase D1 | 0.0368025 |
| RPL4 | ribosomal protein L4 | 0.0366307 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0364808 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0362565 |
| CUL4B | cullin 4B | 0.0357261 |
| ZNF711 | zinc finger protein 711 | 0.0354941 |
| SRP54 | signal recognition particle 54kDa | 0.0351639 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0349353 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0346034 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0343928 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0341938 |
| ZNF292 | zinc finger protein 292 | 0.0341487 |
| PHIP | pleckstrin homology domain interacting protein | 0.033755 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0336838 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0336692 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0336531 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0334579 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0329433 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0327029 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.03253 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0325265 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0324837 |
| USP25 | ubiquitin specific peptidase 25 | 0.0323797 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0322981 |
| NCKAP1 | NCK-associated protein 1 | 0.0321277 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0321016 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0320945 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0320911 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.031938 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0318727 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0317357 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.031563 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0315124 |
| UBC | ubiquitin C | 0.0314436 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.117991 |
| GPC3 | glypican 3 | -0.101389 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0891737 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0594681 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0565424 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0548055 |
| RPS27A | ribosomal protein S27a | -0.0525332 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0522805 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0486002 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.048092 |
| RPL37A | ribosomal protein L37a | -0.0465748 |
| CENPF | centromere protein F, 350/400kDa | -0.0447063 |
| MT2A | metallothionein 2A | -0.0442343 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.042457 |
| RPS12 | ribosomal protein S12 | -0.0377276 |
| RAD51B | RAD51 paralog B | -0.0353645 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0323452 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0322311 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0321565 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0316931 |
| METAP2 | methionyl aminopeptidase 2 | -0.0316836 |
| TRERF1 | transcriptional regulating factor 1 | -0.0308436 |
| RPS3 | ribosomal protein S3 | -0.0301052 |
| ATXN1 | ataxin 1 | -0.0299376 |
| RPL23 | ribosomal protein L23 | -0.0299368 |
| PRELID2 | PRELI domain containing 2 | -0.0298364 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0296633 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.029397 |
| RPL35A | ribosomal protein L35a | -0.0288743 |
| UTRN | utrophin | -0.0286935 |
| SGO2 | shugoshin 2 | -0.0282631 |
| TNS3 | tensin 3 | -0.0282177 |
| NRG1 | neuregulin 1 | -0.0281796 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0280075 |
| TMEM131 | transmembrane protein 131 | -0.0279291 |
| CADM2 | cell adhesion molecule 2 | -0.0277977 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0276863 |
| SMYD3 | SET and MYND domain containing 3 | -0.0268541 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0264277 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0262414 |
| CENPE | centromere protein E, 312kDa | -0.0261565 |
| RPS16 | ribosomal protein S16 | -0.0259532 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.02574 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0255698 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0253872 |
| RPL18 | ribosomal protein L18 | -0.0253232 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0250503 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0250322 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0245313 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0243506 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0243041 |
| FRMD5 | FERM domain containing 5 | -0.0242046 |
| KIF4A | kinesin family member 4A | -0.0239555 |
| RPLP2 | ribosomal protein, large, P2 | -0.0239077 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0236968 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0235574 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.023169 |
| SQSTM1 | sequestosome 1 | -0.0230434 |
| FRY | furry homolog (Drosophila) | -0.0230144 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0229804 |
| NEBL | nebulette | -0.0228616 |
| MKI67 | marker of proliferation Ki-67 | -0.0228336 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0223997 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0221177 |
| EXOC4 | exocyst complex component 4 | -0.0219803 |
| CPA6 | carboxypeptidase A6 | -0.0219797 |
| VIM | vimentin | -0.0219334 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0218405 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0217094 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0214138 |
| SHROOM3 | shroom family member 3 | -0.0213775 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0213515 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.021255 |
| CDK6 | cyclin-dependent kinase 6 | -0.0211894 |
| FILIP1 | filamin A interacting protein 1 | -0.0210533 |
| LRRC4C | leucine rich repeat containing 4C | -0.0209372 |
| KIF18B | kinesin family member 18B | -0.0207821 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0207371 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0206664 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | -0.0205793 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | -0.0204069 |
| RPLP1 | ribosomal protein, large, P1 | -0.0203312 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0201472 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0201227 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0198424 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0198268 |
| PTH2R | parathyroid hormone 2 receptor | -0.0198235 |
| BRDT | bromodomain, testis-specific | -0.019755 |
| MTIF2 | mitochondrial translational initiation factor 2 | -0.0197311 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0195411 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0191826 |
| TXNRD1 | thioredoxin reductase 1 | -0.019171 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0191161 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0190228 |
| NPAS3 | neuronal PAS domain protein 3 | -0.018992 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0189864 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0189476 |
| TEX11 | testis expressed 11 | -0.0187586 |
| ASPH | aspartate beta-hydroxylase | -0.0187574 |
| DROSHA | drosha, ribonuclease type III | -0.0187214 |
