| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.224228 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.145719 |
| FBL | fibrillarin | 0.140523 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.1025 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0910313 |
| INTS6 | integrator complex subunit 6 | 0.0823103 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0736001 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0704761 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0677337 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0632432 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0566942 |
| SEPTIN9 | septin 9 | 0.0558293 |
| ACTG1 | actin gamma 1 | 0.0553949 |
| NUP98 | nucleoporin 98kDa | 0.0540767 |
| PCBP2 | poly(rC) binding protein 2 | 0.0535901 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.051536 |
| AHNAK | AHNAK nucleoprotein | 0.0514852 |
| ATXN1 | ataxin 1 | 0.0501549 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0498661 |
| DST | dystonin | 0.0496497 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0496386 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0474978 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0458944 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0457682 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0447664 |
| MYO1E | myosin IE | 0.0444054 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0443657 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0424716 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0414021 |
| PTK2 | protein tyrosine kinase 2 | 0.0412767 |
| JMJD1C | jumonji domain containing 1C | 0.0406048 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0403913 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.040213 |
| SFTPA2 | surfactant protein A2 | 0.0400247 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0390457 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0387323 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0385593 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0385322 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0380319 |
| SETD5 | SET domain containing 5 | 0.0377542 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0376271 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0370655 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0369749 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0367872 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.035792 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0355962 |
| CTBP2 | C-terminal binding protein 2 | 0.0347788 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0344749 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0341165 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0337167 |
| VMP1 | vacuole membrane protein 1 | 0.0330512 |
| SIK3 | SIK family kinase 3 | 0.0327775 |
| ATF6 | activating transcription factor 6 | 0.0326422 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0324856 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0324642 |
| UBAP2 | ubiquitin associated protein 2 | 0.0323913 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.03226 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0318998 |
| HDAC9 | histone deacetylase 9 | 0.0306432 |
| BMP6 | bone morphogenetic protein 6 | 0.0304373 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0303383 |
| USP34 | ubiquitin specific peptidase 34 | 0.0302257 |
| MCL1 | myeloid cell leukemia 1 | 0.0298357 |
| OGA | O-GlcNAcase | 0.0294979 |
| TPM3 | tropomyosin 3 | 0.0290383 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0289344 |
| ASPH | aspartate beta-hydroxylase | 0.0286179 |
| ERBIN | erbb2 interacting protein | 0.0282954 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0282844 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0281204 |
| RSU1 | Ras suppressor protein 1 | 0.0280944 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0280584 |
| MSN | moesin | 0.0271642 |
| TAOK1 | TAO kinase 1 | 0.0271323 |
| CDK13 | cyclin-dependent kinase 13 | 0.0271111 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0270031 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0270005 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0269435 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0268816 |
| ZNF644 | zinc finger protein 644 | 0.0268456 |
| RAD51B | RAD51 paralog B | 0.026768 |
| ANO6 | anoctamin 6 | 0.0265802 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0264598 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0262227 |
| SETX | senataxin | 0.0261639 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0260677 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0260217 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0259838 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0257648 |
| TNS3 | tensin 3 | 0.0257547 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.025709 |
| GOLGB1 | golgin B1 | 0.0255596 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0255455 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0254944 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0252414 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.025134 |
| ZNF638 | zinc finger protein 638 | 0.0249546 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.024941 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0249211 |
| BRD2 | bromodomain containing 2 | 0.0246282 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.229739 |
| RPS16 | ribosomal protein S16 | -0.182342 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0968502 |
| CD44 | CD44 molecule (Indian blood group) | -0.0943283 |
| PTMA | prothymosin, alpha | -0.0916337 |
| TMSB10 | thymosin beta 10 | -0.0702282 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0663859 |
| RPLP2 | ribosomal protein, large, P2 | -0.0585487 |
| RPS24 | ribosomal protein S24 | -0.0529081 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0529043 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0508458 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0448091 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0447805 |
| ACTN4 | actinin, alpha 4 | -0.0443879 |
| ANXA2 | annexin A2 | -0.0427354 |
| MT2A | metallothionein 2A | -0.0419183 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0415731 |
| RPL35A | ribosomal protein L35a | -0.040444 |
| RPLP1 | ribosomal protein, large, P1 | -0.039344 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0382798 |
| RPL37A | ribosomal protein L37a | -0.0371501 |
| CTSD | cathepsin D | -0.0359439 |
| RTN4 | reticulon 4 | -0.0358279 |
| AFAP1 | actin filament associated protein 1 | -0.033618 |
| RPS27A | ribosomal protein S27a | -0.0332742 |
| S100A6 | S100 calcium binding protein A6 | -0.0327145 |
| RPL36A | ribosomal protein L36a | -0.0315748 |
| TMEM123 | transmembrane protein 123 | -0.0314624 |
| RPS12 | ribosomal protein S12 | -0.0306932 |
| RPS3 | ribosomal protein S3 | -0.0299872 |
| CAVIN1 | caveolae associated protein 1 | -0.0291307 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0289879 |
| RPS25 | ribosomal protein S25 | -0.0260326 |
| TXNRD1 | thioredoxin reductase 1 | -0.0258978 |
| RPL12 | ribosomal protein L12 | -0.0252727 |
| RPL28 | ribosomal protein L28 | -0.0252246 |
| RPL38 | ribosomal protein L38 | -0.0246448 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0244203 |
| RPL11 | ribosomal protein L11 | -0.0244031 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0242656 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0233887 |
| TUBB | tubulin, beta class I | -0.0222893 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0222858 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0221347 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0220525 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0218737 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0217671 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.02166 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0216281 |
| RPS29 | ribosomal protein S29 | -0.0215219 |
| RPS8 | ribosomal protein S8 | -0.0213551 |
| RPLP0 | ribosomal protein, large, P0 | -0.0212974 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0212916 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0210967 |
| S100A10 | S100 calcium binding protein A10 | -0.0193866 |
| PGK1 | phosphoglycerate kinase 1 | -0.0193519 |
| RPL26 | ribosomal protein L26 | -0.0192668 |
| MKI67 | marker of proliferation Ki-67 | -0.0192311 |
| RPS6 | ribosomal protein S6 | -0.0191211 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0188506 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0186123 |
| GNAS | GNAS complex locus | -0.018461 |
| RPL27A | ribosomal protein L27a | -0.0182852 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0182682 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0181346 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0180866 |
| RPL30 | ribosomal protein L30 | -0.0174558 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0172599 |
| KLF6 | Kruppel-like factor 6 | -0.0171795 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0168197 |
| RPS13 | ribosomal protein S13 | -0.0165293 |
| RPL34 | ribosomal protein L34 | -0.0165236 |
| YBX1 | Y box binding protein 1 | -0.0164617 |
| HLA-B | major histocompatibility complex, class I, B | -0.0164297 |
| RPS19 | ribosomal protein S19 | -0.016322 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0162334 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0161277 |
| RPL7A | ribosomal protein L7a | -0.0160584 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0159113 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.01587 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0157948 |
| KNOP1 | lysine-rich nucleolar protein 1 | -0.0157915 |
| RPS27 | ribosomal protein S27 | -0.015773 |
| RPS21 | ribosomal protein S21 | -0.015637 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0154193 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0153912 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0153209 |
| IER3 | immediate early response 3 | -0.0151764 |
| ANLN | anillin, actin binding protein | -0.015051 |
| H1-0 | H1.0 linker histone | -0.0149974 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0149079 |
| NPR2 | natriuretic peptide receptor 2 | -0.0147235 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0146396 |
| ANGPTL4 | angiopoietin-like 4 | -0.014626 |
| RPL36 | ribosomal protein L36 | -0.0146002 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0145963 |
| SLC38A2 | solute carrier family 38, member 2 | -0.01458 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.014515 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0142262 |
| LMNA | lamin A/C | -0.014136 |
