| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD6 | FERM domain containing 6 | 0.237194 |
| HDAC9 | histone deacetylase 9 | 0.159209 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.15273 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.093186 |
| ACTG1 | actin gamma 1 | 0.0931363 |
| HMGA2 | high mobility group AT-hook 2 | 0.0893298 |
| NAV3 | neuron navigator 3 | 0.0789508 |
| ZNF438 | zinc finger protein 438 | 0.0759667 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0748725 |
| NABP1 | nucleic acid binding protein 1 | 0.0709013 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0644322 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0615441 |
| FRMD4A | FERM domain containing 4A | 0.0608346 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0607636 |
| RPS12 | ribosomal protein S12 | 0.0603725 |
| INTS6 | integrator complex subunit 6 | 0.0603287 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0591363 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0517026 |
| DGKI | diacylglycerol kinase, iota | 0.0506917 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0476801 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0468085 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0461299 |
| FNIP1 | folliculin interacting protein 1 | 0.0451198 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0444941 |
| RCOR1 | REST corepressor 1 | 0.0435248 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0429024 |
| RPS3 | ribosomal protein S3 | 0.0415331 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0405578 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0397304 |
| SGMS2 | sphingomyelin synthase 2 | 0.0383588 |
| GPATCH2L | G patch domain containing 2-like | 0.0381045 |
| NAV2 | neuron navigator 2 | 0.037668 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0364701 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0357871 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0342987 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0342716 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0338678 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0338677 |
| RAD51B | RAD51 paralog B | 0.0323338 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0320052 |
| FKBP15 | FK506 binding protein 15, 133kDa | 0.0300967 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0295864 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0295093 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0294401 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0294387 |
| GOLGA2 | golgin A2 | 0.028848 |
| BPTF | bromodomain PHD finger transcription factor | 0.0287308 |
| RPL35A | ribosomal protein L35a | 0.02856 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0284007 |
| EXOC4 | exocyst complex component 4 | 0.0281742 |
| JMJD1C | jumonji domain containing 1C | 0.0273487 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0272184 |
| HM13 | histocompatibility (minor) 13 | 0.0263798 |
| PCNX4 | pecanex 4 | 0.026208 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0262047 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0260555 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0259432 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0256483 |
| CAPRIN2 | caprin family member 2 | 0.0253775 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0250215 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0245102 |
| CAST | calpastatin | 0.0242513 |
| SP100 | SP100 nuclear antigen | 0.0241958 |
| GOLGB1 | golgin B1 | 0.0241021 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0239954 |
| SMYD3 | SET and MYND domain containing 3 | 0.0238786 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0237488 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0236596 |
| AEBP2 | AE binding protein 2 | 0.0228299 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0221624 |
| SETX | senataxin | 0.0214993 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0214457 |
| SEC24D | SEC24 family member D | 0.0211645 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0210899 |
| UBAP2 | ubiquitin associated protein 2 | 0.0210001 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | 0.0208999 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0208912 |
| SCFD1 | sec1 family domain containing 1 | 0.0208589 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0208494 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0205367 |
| DENND1A | DENN/MADD domain containing 1A | 0.0204559 |
| SQSTM1 | sequestosome 1 | 0.020344 |
| PGM3 | phosphoglucomutase 3 | 0.0201629 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0200443 |
| RPL13A | ribosomal protein L13a | 0.0197814 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0196816 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0196749 |
| RPL26 | ribosomal protein L26 | 0.0196347 |
| MSH4 | mutS homolog 4 | 0.0195595 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0195188 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.01949 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0194853 |
| PMM2 | phosphomannomutase 2 | 0.0194403 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0193446 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.019236 |
| CMIP | c-Maf inducing protein | 0.0192089 |
| PUM3 | pumilio RNA binding family member 3 | 0.0190319 |
| FHIT | fragile histidine triad | 0.0187768 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0187473 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0187456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.156657 |
| MT2A | metallothionein 2A | -0.122298 |
| UBC | ubiquitin C | -0.113382 |
| TMSB10 | thymosin beta 10 | -0.105396 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.095955 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0927723 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.084518 |
| TXNRD1 | thioredoxin reductase 1 | -0.0725827 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0686482 |
| JUN | jun proto-oncogene | -0.0666809 |
| HMGA1 | high mobility group AT-hook 1 | -0.0653888 |
| RPL8 | ribosomal protein L8 | -0.064835 |
| PKM | pyruvate kinase, muscle | -0.0633268 |
| STC1 | stanniocalcin 1 | -0.0608756 |
| UPP1 | uridine phosphorylase 1 | -0.0603855 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0587317 |
| RPS27A | ribosomal protein S27a | -0.0540041 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0519088 |
| RPLP1 | ribosomal protein, large, P1 | -0.0500344 |
| PTMA | prothymosin, alpha | -0.049026 |
| AHNAK | AHNAK nucleoprotein | -0.0478887 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0478863 |
| FTL | ferritin, light polypeptide | -0.0473889 |
| RPL23 | ribosomal protein L23 | -0.0467506 |
| PTK2 | protein tyrosine kinase 2 | -0.0464048 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0453346 |
| RTN4 | reticulon 4 | -0.0450969 |
| USP3 | ubiquitin specific peptidase 3 | -0.0442741 |
| RPL32 | ribosomal protein L32 | -0.043471 |
| TOP1 | topoisomerase (DNA) I | -0.0424996 |
| TPD52 | tumor protein D52 | -0.0424738 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0402672 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0399525 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0396551 |
| PFN1 | profilin 1 | -0.0390104 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0386867 |
| RPS19 | ribosomal protein S19 | -0.0382938 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0380369 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0371434 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0370713 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0356092 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0354052 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0352918 |
| FOSL1 | FOS-like antigen 1 | -0.0352078 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0345816 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.034578 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0341689 |
| RPS21 | ribosomal protein S21 | -0.0338215 |
| CD44 | CD44 molecule (Indian blood group) | -0.0336829 |
| RPS6 | ribosomal protein S6 | -0.0330636 |
| PGK1 | phosphoglycerate kinase 1 | -0.0324947 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0322006 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0321876 |
| RBM25 | RNA binding motif protein 25 | -0.031593 |
| MATR3 | matrin 3 | -0.0313306 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0310945 |
| ENO1 | enolase 1, (alpha) | -0.0302406 |
| PHIP | pleckstrin homology domain interacting protein | -0.0295267 |
| S100A9 | S100 calcium binding protein A9 | -0.0290987 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0288263 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0285958 |
| FOXO3 | forkhead box O3 | -0.028213 |
| RPS24 | ribosomal protein S24 | -0.0281753 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0281468 |
| RPS5 | ribosomal protein S5 | -0.0279061 |
| RBM39 | RNA binding motif protein 39 | -0.0276509 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0275876 |
| FLNB | filamin B, beta | -0.0271236 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0269746 |
| SNX9 | sorting nexin 9 | -0.0268353 |
| SRPK2 | SRSF protein kinase 2 | -0.0267625 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0264954 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0263244 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0262971 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0262408 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0260793 |
| NOP58 | NOP58 ribonucleoprotein | -0.026058 |
| TPX2 | TPX2, microtubule-associated | -0.0260393 |
| GNAS | GNAS complex locus | -0.0258611 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0257536 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0257375 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0256441 |
| FHL2 | four and a half LIM domains 2 | -0.0255216 |
| G0S2 | G0/G1 switch 2 | -0.0255081 |
| LAMB3 | laminin, beta 3 | -0.0255 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0254341 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0254337 |
| LDHB | lactate dehydrogenase B | -0.0252697 |
| ZNF292 | zinc finger protein 292 | -0.0252473 |
| RNF145 | ring finger protein 145 | -0.0249905 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0246109 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0245253 |
| XPO1 | exportin 1 | -0.0244814 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.024187 |
| TPM4 | tropomyosin 4 | -0.0240853 |
| TMEM123 | transmembrane protein 123 | -0.0239378 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0238461 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0236384 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.023628 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.023532 |
