| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tubulin inhibitor 6_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.094513 |
| POTEF | POTE ankyrin domain family, member F | 0.0850193 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0790719 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0745951 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0700547 |
| ANXA1 | annexin A1 | 0.0671687 |
| PCBP2 | poly(rC) binding protein 2 | 0.0611558 |
| ZNF608 | zinc finger protein 608 | 0.0555829 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0538298 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0523206 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0512803 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0512607 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0505627 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0449917 |
| MYOF | myoferlin | 0.0438316 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0436087 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0415288 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0397232 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0386684 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0379843 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0374088 |
| FER1L6 | fer-1-like family member 6 | 0.0371328 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0360902 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0354374 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0351693 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0344418 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0335197 |
| PDGFC | platelet derived growth factor C | 0.033518 |
| ECT2 | epithelial cell transforming 2 | 0.0333737 |
| YAP1 | Yes-associated protein 1 | 0.0330725 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.032503 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.032435 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0312144 |
| TPM3 | tropomyosin 3 | 0.0304922 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0302544 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0302491 |
| VMP1 | vacuole membrane protein 1 | 0.0302149 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0300219 |
| INTS6 | integrator complex subunit 6 | 0.0297076 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0295848 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0283646 |
| ACTG1 | actin gamma 1 | 0.0281775 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0281717 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0277267 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0275013 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0274246 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.027412 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0273618 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0271893 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0270904 |
| AEBP2 | AE binding protein 2 | 0.0268002 |
| DIAPH1 | diaphanous-related formin 1 | 0.0266455 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0265902 |
| EZR | ezrin | 0.0265252 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0261706 |
| RPS12 | ribosomal protein S12 | 0.0261581 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0261426 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0255671 |
| ENO1 | enolase 1, (alpha) | 0.025477 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0254396 |
| RRM2 | ribonucleotide reductase M2 | 0.0254 |
| RCOR1 | REST corepressor 1 | 0.0252457 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0252018 |
| FAM168A | family with sequence similarity 168, member A | 0.0251593 |
| USP47 | ubiquitin specific peptidase 47 | 0.025157 |
| CORO1C | coronin, actin binding protein, 1C | 0.0250459 |
| MACROD2 | MACRO domain containing 2 | 0.0248964 |
| BRD2 | bromodomain containing 2 | 0.0247519 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0246564 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0245514 |
| MLIP | muscular LMNA-interacting protein | 0.0245386 |
| RBM5 | RNA binding motif protein 5 | 0.0239959 |
| CRY1 | cryptochrome circadian clock 1 | 0.0239907 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0239253 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0237027 |
| SGMS2 | sphingomyelin synthase 2 | 0.0236251 |
| ATOSA | atos homolog A | 0.0232711 |
| CCNL1 | cyclin L1 | 0.0230061 |
| CCNY | cyclin Y | 0.0229489 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0226548 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0223257 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0222527 |
| B2M | beta-2-microglobulin | 0.0211137 |
| FNIP1 | folliculin interacting protein 1 | 0.0209327 |
| VEGFA | vascular endothelial growth factor A | 0.0208753 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0207695 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0206184 |
| HDGF | hepatoma-derived growth factor | 0.0204369 |
| SEPTIN9 | septin 9 | 0.0203805 |
| PLK2 | polo-like kinase 2 | 0.0203783 |
| RPL3 | ribosomal protein L3 | 0.0203193 |
| ANLN | anillin, actin binding protein | 0.0203142 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0202674 |
| UBC | ubiquitin C | 0.0202081 |
| PUM1 | pumilio RNA-binding family member 1 | 0.020143 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0199834 |
| KIF5C | kinesin family member 5C | 0.0199273 |
| JMJD1C | jumonji domain containing 1C | 0.0198469 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0197826 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0191808 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181464 |
| PTMA | prothymosin, alpha | -0.151856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.132408 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.11794 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.105924 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0995091 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0893856 |
| TXNRD1 | thioredoxin reductase 1 | -0.0884425 |
| FLNB | filamin B, beta | -0.087992 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0843724 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0838882 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0807427 |
| TMSB4X | thymosin beta 4, X-linked | -0.0787167 |
| NBEA | neurobeachin | -0.070522 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.070313 |
| RPL34 | ribosomal protein L34 | -0.066598 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.063427 |
| S100A6 | S100 calcium binding protein A6 | -0.0630517 |
| BMP10 | bone morphogenetic protein 10 | -0.0626806 |
| RPS24 | ribosomal protein S24 | -0.0612482 |
| RPLP0 | ribosomal protein, large, P0 | -0.0586796 |
| CCND1 | cyclin D1 | -0.0577974 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0573636 |
| RPLP1 | ribosomal protein, large, P1 | -0.0557364 |
| RPS23 | ribosomal protein S23 | -0.0556753 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0556077 |
| RPL11 | ribosomal protein L11 | -0.0554373 |
| RPL35A | ribosomal protein L35a | -0.0553235 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0528401 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0507812 |
| OSMR | oncostatin M receptor | -0.0507409 |
| PYGB | phosphorylase, glycogen; brain | -0.0503333 |
| S100A4 | S100 calcium binding protein A4 | -0.0501448 |
| RPS21 | ribosomal protein S21 | -0.0499887 |
| NF1 | neurofibromin 1 | -0.0497377 |
| NFIA | nuclear factor I/A | -0.0479025 |
| GOLGA4 | golgin A4 | -0.0469693 |
| GNAS | GNAS complex locus | -0.0468512 |
| SMYD3 | SET and MYND domain containing 3 | -0.0448716 |
| RPL12 | ribosomal protein L12 | -0.0441327 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.043747 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.043509 |
| RPL32 | ribosomal protein L32 | -0.0416069 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0412666 |
| EXOC6B | exocyst complex component 6B | -0.0397014 |
| RPL31 | ribosomal protein L31 | -0.0396934 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0373507 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0370917 |
| S100A10 | S100 calcium binding protein A10 | -0.0354672 |
| ENOSF1 | enolase superfamily member 1 | -0.0353918 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0353826 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0353794 |
| RPL26 | ribosomal protein L26 | -0.0353288 |
| RPS6 | ribosomal protein S6 | -0.0351609 |
| RPS19 | ribosomal protein S19 | -0.0349104 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0343418 |
| ANK2 | ankyrin 2, neuronal | -0.0339703 |
| EFNA5 | ephrin-A5 | -0.0338925 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0338741 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0337942 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.033657 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0334369 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0334285 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0333706 |
| TMSB10 | thymosin beta 10 | -0.0332664 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.033244 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0330825 |
| RHBDD1 | rhomboid domain containing 1 | -0.03184 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0316448 |
| METTL15 | methyltransferase like 15 | -0.0312645 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0311698 |
| RTN4 | reticulon 4 | -0.0310146 |
| TMEM263 | transmembrane protein 263 | -0.0309006 |
| SBF2 | SET binding factor 2 | -0.0305489 |
| NEBL | nebulette | -0.0303378 |
| RRBP1 | ribosome binding protein 1 | -0.0301834 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0300019 |
| RPL13A | ribosomal protein L13a | -0.0297496 |
| RPS27A | ribosomal protein S27a | -0.0297002 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0291529 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.028821 |
| PGK1 | phosphoglycerate kinase 1 | -0.0287126 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0285131 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0278586 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0278437 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0277878 |
| RPL9 | ribosomal protein L9 | -0.0275226 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0272855 |
| DIAPH2 | diaphanous-related formin 2 | -0.0272591 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0269778 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.026793 |
| RPL27A | ribosomal protein L27a | -0.0262692 |
| HJURP | Holliday junction recognition protein | -0.0261688 |
| DGKH | diacylglycerol kinase, eta | -0.0254736 |
| MAP4 | microtubule-associated protein 4 | -0.0252468 |
| VCL | vinculin | -0.0250639 |
| RPL5 | ribosomal protein L5 | -0.0250309 |
| GPHN | gephyrin | -0.0249209 |
| EHBP1 | EH domain binding protein 1 | -0.0248863 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0248859 |