| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.227948 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.141474 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.11944 |
| HDAC9 | histone deacetylase 9 | 0.0986719 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0907283 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0860251 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0852117 |
| NAV2 | neuron navigator 2 | 0.0817594 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0804392 |
| ATXN1 | ataxin 1 | 0.080271 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0735128 |
| KYNU | kynureninase | 0.073412 |
| ARRDC3 | arrestin domain containing 3 | 0.0726949 |
| VCL | vinculin | 0.0703044 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0697103 |
| FNIP1 | folliculin interacting protein 1 | 0.0689424 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0687372 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0650829 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0635441 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0634855 |
| VEGFA | vascular endothelial growth factor A | 0.058297 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0572722 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0566845 |
| SDC4 | syndecan 4 | 0.0564053 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0555962 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0540282 |
| PCBP2 | poly(rC) binding protein 2 | 0.0538978 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0502417 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0494817 |
| OGA | O-GlcNAcase | 0.0492367 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0485354 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0473464 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0455368 |
| SMAD3 | SMAD family member 3 | 0.0455098 |
| DST | dystonin | 0.0446836 |
| PDE10A | phosphodiesterase 10A | 0.0440401 |
| VMP1 | vacuole membrane protein 1 | 0.0429784 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0428759 |
| JMJD1C | jumonji domain containing 1C | 0.042767 |
| AHNAK | AHNAK nucleoprotein | 0.0425487 |
| MSN | moesin | 0.0425001 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0421147 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0412214 |
| PRELID2 | PRELI domain containing 2 | 0.0409936 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0399179 |
| LDHA | lactate dehydrogenase A | 0.0396761 |
| INTS6 | integrator complex subunit 6 | 0.0392383 |
| SPAG9 | sperm associated antigen 9 | 0.0390582 |
| MYOF | myoferlin | 0.0383718 |
| DUSP10 | dual specificity phosphatase 10 | 0.0380198 |
| BICC1 | BicC family RNA binding protein 1 | 0.0378291 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0376973 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0373064 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0363032 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0353784 |
| GPC6 | glypican 6 | 0.0348876 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0347446 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0340579 |
| WTAP | Wilms tumor 1 associated protein | 0.0333246 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0328919 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0328558 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0326834 |
| SFTPA2 | surfactant protein A2 | 0.0323147 |
| RUNX1 | runt-related transcription factor 1 | 0.0321989 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0321326 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0319202 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0313574 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0311144 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0310641 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0308157 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0305692 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0297853 |
| CCNL1 | cyclin L1 | 0.0295759 |
| STC2 | stanniocalcin 2 | 0.0293496 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0290952 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0289102 |
| SMYD3 | SET and MYND domain containing 3 | 0.0288897 |
| APP | amyloid beta (A4) precursor protein | 0.0287533 |
| CDK19 | cyclin-dependent kinase 19 | 0.0286324 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0278185 |
| SNX9 | sorting nexin 9 | 0.0276418 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0271359 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.027038 |
| FAM20C | family with sequence similarity 20, member C | 0.026859 |
| CEP250 | centrosomal protein 250kDa | 0.0267277 |
| TPM3 | tropomyosin 3 | 0.0266498 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0263175 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0261744 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0256637 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0254336 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0249978 |
| PCBP3 | poly(rC) binding protein 3 | 0.0248137 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0247914 |
| GOLGB1 | golgin B1 | 0.0247768 |
| HELZ | helicase with zinc finger | 0.0245108 |
| CREBRF | CREB3 regulatory factor | 0.0244713 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0244397 |
| OPTN | optineurin | 0.0241887 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0241826 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0240141 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.298142 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.129427 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.118186 |
| FTL | ferritin, light polypeptide | -0.103542 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.10001 |
| IER3 | immediate early response 3 | -0.0996334 |
| TMSB10 | thymosin beta 10 | -0.0954133 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0867453 |
| FRMD4A | FERM domain containing 4A | -0.0791755 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0789555 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0774126 |
| HLA-B | major histocompatibility complex, class I, B | -0.0602149 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0600701 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0567175 |
| NDRG1 | N-myc downstream regulated 1 | -0.0560162 |
| GNAS | GNAS complex locus | -0.0530358 |
| PTMA | prothymosin, alpha | -0.0521266 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0509675 |
| MT2A | metallothionein 2A | -0.0509182 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0506583 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0499122 |
| HLA-A | major histocompatibility complex, class I, A | -0.0496121 |
| RPS24 | ribosomal protein S24 | -0.0494922 |
| RPL37A | ribosomal protein L37a | -0.0455692 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0434495 |
| RPL35A | ribosomal protein L35a | -0.0424287 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0419444 |
| RPLP2 | ribosomal protein, large, P2 | -0.0404961 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0402658 |
| RPS6 | ribosomal protein S6 | -0.0401378 |
| RPLP1 | ribosomal protein, large, P1 | -0.0390927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0384708 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0373019 |
| CTSD | cathepsin D | -0.035877 |
| RAI14 | retinoic acid induced 14 | -0.0356989 |
| RPS23 | ribosomal protein S23 | -0.034596 |
| PGK1 | phosphoglycerate kinase 1 | -0.0343557 |
| RPS8 | ribosomal protein S8 | -0.0336453 |
| RPL38 | ribosomal protein L38 | -0.0334305 |
| EGR1 | early growth response 1 | -0.032538 |
| HMGA1 | high mobility group AT-hook 1 | -0.0324117 |
| RPS13 | ribosomal protein S13 | -0.0323187 |
| ADM | adrenomedullin | -0.0316837 |
| RPL36A | ribosomal protein L36a | -0.0310427 |
| GLIS3 | GLIS family zinc finger 3 | -0.0303313 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0300937 |
| TPM4 | tropomyosin 4 | -0.0295439 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0292375 |
| CAVIN1 | caveolae associated protein 1 | -0.028942 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0288445 |
| RPS29 | ribosomal protein S29 | -0.0282268 |
| RPS27A | ribosomal protein S27a | -0.0281401 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0281359 |
| RPL31 | ribosomal protein L31 | -0.0277561 |
| CLMP | CXADR-like membrane protein | -0.0274056 |
| LOX | lysyl oxidase | -0.0273985 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0270446 |
| NRN1 | neuritin 1 | -0.0262385 |
| RPS19 | ribosomal protein S19 | -0.0260239 |
| RPL36 | ribosomal protein L36 | -0.0258136 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.024827 |
| CD44 | CD44 molecule (Indian blood group) | -0.0247977 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0247651 |
| KRT19 | keratin 19, type I | -0.0242368 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0241819 |
| RRBP1 | ribosome binding protein 1 | -0.0241593 |
| RPL34 | ribosomal protein L34 | -0.023584 |
| RACK1 | receptor for activated C kinase 1 | -0.0234163 |
| EGFR | epidermal growth factor receptor | -0.023104 |
| RPL9 | ribosomal protein L9 | -0.0229525 |
| TUBB | tubulin, beta class I | -0.0225999 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0223586 |
| RPS25 | ribosomal protein S25 | -0.0222003 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0221448 |
| TMSB4X | thymosin beta 4, X-linked | -0.0221218 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0220114 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0217873 |
| RPS14 | ribosomal protein S14 | -0.021673 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0213253 |
| VCAN | versican | -0.0211083 |
| LSAMP | limbic system-associated membrane protein | -0.0209022 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -0.0206605 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0206017 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0205668 |
| RPS3 | ribosomal protein S3 | -0.0205646 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0204612 |
| RPL11 | ribosomal protein L11 | -0.0204112 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0203898 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0200466 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0197619 |
| RPL32 | ribosomal protein L32 | -0.0197108 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0196029 |
| EFNA5 | ephrin-A5 | -0.0195623 |
| RPS12 | ribosomal protein S12 | -0.0193906 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0191839 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0191346 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0191073 |
| CP | ceruloplasmin (ferroxidase) | -0.0187948 |
| TENM2 | teneurin transmembrane protein 2 | -0.0187746 |
| RPL37 | ribosomal protein L37 | -0.0187633 |
