| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT8 | keratin 8, type II | 0.181558 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.119043 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.116723 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.108291 |
| SDC4 | syndecan 4 | 0.102615 |
| AHNAK | AHNAK nucleoprotein | 0.101506 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0947636 |
| NEBL | nebulette | 0.0931368 |
| KRT18 | keratin 18, type I | 0.0882627 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0874638 |
| ACTG1 | actin gamma 1 | 0.0839898 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0823281 |
| FAT1 | FAT atypical cadherin 1 | 0.0807232 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0763413 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0742381 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0740452 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0720408 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0668655 |
| LDHA | lactate dehydrogenase A | 0.0658591 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0648035 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0633825 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.062091 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0616074 |
| DSPP | dentin sialophosphoprotein | 0.0610058 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0594341 |
| TRIM2 | tripartite motif containing 2 | 0.0581754 |
| CTBP2 | C-terminal binding protein 2 | 0.0578337 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0573095 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0558629 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.055566 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0552145 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.054965 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0542798 |
| RPS12 | ribosomal protein S12 | 0.0540439 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0532386 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0531494 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.052709 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0526446 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0521248 |
| SMAD3 | SMAD family member 3 | 0.0519502 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0512228 |
| SERINC5 | serine incorporator 5 | 0.0509803 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0499128 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0493645 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0493536 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0491313 |
| CANX | calnexin | 0.0487526 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0485569 |
| EHBP1 | EH domain binding protein 1 | 0.0480096 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0475796 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0473099 |
| BCL2L1 | BCL2-like 1 | 0.0472204 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.046955 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0468856 |
| MYO1E | myosin IE | 0.046669 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0463076 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.044829 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0444649 |
| ACTN4 | actinin, alpha 4 | 0.0444367 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0443719 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0443615 |
| RPS3 | ribosomal protein S3 | 0.0442225 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0436682 |
| ZNRF3 | zinc and ring finger 3 | 0.0434714 |
| HDLBP | high density lipoprotein binding protein | 0.0434027 |
| ANXA2 | annexin A2 | 0.0428746 |
| SMAD2 | SMAD family member 2 | 0.0421331 |
| RAB10 | RAB10, member RAS oncogene family | 0.0421142 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0412911 |
| VCL | vinculin | 0.0412838 |
| CADPS | Ca++-dependent secretion activator | 0.0411503 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0403654 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0400589 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0396277 |
| APP | amyloid beta (A4) precursor protein | 0.0388289 |
| YAP1 | Yes-associated protein 1 | 0.0388118 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0382988 |
| ETV6 | ets variant 6 | 0.0380666 |
| MYOF | myoferlin | 0.0380157 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0373795 |
| TMEM123 | transmembrane protein 123 | 0.0372434 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0364521 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0363197 |
| EXOC4 | exocyst complex component 4 | 0.035682 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0355541 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0352772 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0351724 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0349433 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0349336 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0341508 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0340993 |
| TOP1 | topoisomerase (DNA) I | 0.0340571 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0337514 |
| LOC112694756 | uncharaterized LOC112694756 | 0.033716 |
| SQSTM1 | sequestosome 1 | 0.0336167 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0334953 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.0328291 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0327947 |
| MYO10 | myosin X | 0.0324515 |
| PARD3B | par-3 family cell polarity regulator beta | 0.032444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.291138 |
| TMSB10 | thymosin beta 10 | -0.117314 |
| PTMA | prothymosin, alpha | -0.081332 |
| CST3 | cystatin C | -0.0681058 |
| RPL31 | ribosomal protein L31 | -0.05324 |
| RPS6 | ribosomal protein S6 | -0.0407153 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0403438 |
| NDRG1 | N-myc downstream regulated 1 | -0.0383843 |
| RPS5 | ribosomal protein S5 | -0.0379404 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0332305 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0323732 |
| HMGA1 | high mobility group AT-hook 1 | -0.0315763 |
| CLDN3 | claudin 3 | -0.0301932 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0290488 |
| RPL32 | ribosomal protein L32 | -0.0286911 |
| S100A10 | S100 calcium binding protein A10 | -0.0281512 |
| RPS2 | ribosomal protein S2 | -0.0265225 |
| CCND1 | cyclin D1 | -0.0259294 |
| RPL28 | ribosomal protein L28 | -0.0252812 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0252366 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0246524 |
| HLA-A | major histocompatibility complex, class I, A | -0.0242658 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.023337 |
| EGR1 | early growth response 1 | -0.0229376 |
| RPS23 | ribosomal protein S23 | -0.0229226 |
| S100A2 | S100 calcium binding protein A2 | -0.0228579 |
| RBM39 | RNA binding motif protein 39 | -0.0227553 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0225096 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0224706 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.02244 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0222297 |
| RPS29 | ribosomal protein S29 | -0.0219157 |
| ZNF706 | zinc finger protein 706 | -0.0217211 |
| MXD1 | MAX dimerization protein 1 | -0.0213307 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0212827 |
| RNF145 | ring finger protein 145 | -0.0211849 |
| FOSL1 | FOS-like antigen 1 | -0.0209145 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0198798 |
| PERP | PERP, TP53 apoptosis effector | -0.0195946 |
| RPL11 | ribosomal protein L11 | -0.0193881 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0185884 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0184426 |
| DUSP5 | dual specificity phosphatase 5 | -0.0183151 |
| RPLP1 | ribosomal protein, large, P1 | -0.0181911 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0181417 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0180427 |
| RYBP | RING1 and YY1 binding protein | -0.0179187 |
| PKM | pyruvate kinase, muscle | -0.0178567 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0177217 |
| ZFP36 | ZFP36 ring finger protein | -0.0176144 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0173086 |
| RPL38 | ribosomal protein L38 | -0.0171516 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0169435 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0167624 |
| NOP58 | NOP58 ribonucleoprotein | -0.0167601 |
| TFG | TRK-fused gene | -0.0167202 |
| RPS13 | ribosomal protein S13 | -0.0165144 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0164086 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0163909 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0163781 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0161718 |
| THOC2 | THO complex 2 | -0.016054 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0159047 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.015772 |
| RNF149 | ring finger protein 149 | -0.0157376 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0157054 |
| GNAS | GNAS complex locus | -0.0151546 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0150227 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0150184 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0150048 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0148803 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0147525 |
| RPS11 | ribosomal protein S11 | -0.0144717 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0144357 |
| RPL21 | ribosomal protein L21 | -0.0144043 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0143478 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0143174 |
| GOLGA4 | golgin A4 | -0.0143152 |
| EDN1 | endothelin 1 | -0.0142631 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0142317 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0141855 |
| MKI67 | marker of proliferation Ki-67 | -0.0141497 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0140947 |
| UPP1 | uridine phosphorylase 1 | -0.0140037 |
| PFN1 | profilin 1 | -0.013993 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0138551 |
| HDGF | hepatoma-derived growth factor | -0.0138331 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.0136887 |
| H1-4 | H1.4 linker histone, cluster member | -0.0135942 |
| CCNK | cyclin K | -0.0135867 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0135659 |
| SRPK2 | SRSF protein kinase 2 | -0.0135374 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0135326 |
| RPS15 | ribosomal protein S15 | -0.0134542 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0134282 |
| NKTR | natural killer cell triggering receptor | -0.0133988 |
| FAM168B | family with sequence similarity 168, member B | -0.0133891 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0133605 |
| RNF114 | ring finger protein 114 | -0.0133575 |
| FMR1 | fragile X mental retardation 1 | -0.0133553 |
