| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tubulin inhibitor 6_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.081423 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0743718 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0636806 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0616889 |
| ATXN1 | ataxin 1 | 0.0604104 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0575456 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0554948 |
| EGFR | epidermal growth factor receptor | 0.0553196 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0515324 |
| AHNAK | AHNAK nucleoprotein | 0.0450869 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0446707 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0436244 |
| MYO5B | myosin VB | 0.0416901 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0410939 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0388396 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0382441 |
| LDHA | lactate dehydrogenase A | 0.0375992 |
| SDC4 | syndecan 4 | 0.0370268 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0365023 |
| NUP50 | nucleoporin 50kDa | 0.0360244 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.035608 |
| YAP1 | Yes-associated protein 1 | 0.0340398 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0338829 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0318319 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0314447 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0310307 |
| RPS12 | ribosomal protein S12 | 0.0305813 |
| SMAD3 | SMAD family member 3 | 0.0304793 |
| RCOR1 | REST corepressor 1 | 0.0304485 |
| SNX9 | sorting nexin 9 | 0.0302662 |
| FHL2 | four and a half LIM domains 2 | 0.0301942 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0300706 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0298431 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0298174 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0296579 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0293339 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0293077 |
| SEPTIN9 | septin 9 | 0.0277472 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.027683 |
| SGMS2 | sphingomyelin synthase 2 | 0.0275736 |
| PCBP2 | poly(rC) binding protein 2 | 0.0273506 |
| POTEF | POTE ankyrin domain family, member F | 0.0267893 |
| CPOX | coproporphyrinogen oxidase | 0.0267816 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0265723 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0265147 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0261937 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0255751 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.025475 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0253215 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0250856 |
| AREG | amphiregulin | 0.0250174 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0242992 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0242959 |
| CALU | calumenin | 0.0242925 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0242096 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.024111 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0239638 |
| SPAG9 | sperm associated antigen 9 | 0.0234728 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0233781 |
| SQSTM1 | sequestosome 1 | 0.0229821 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0229727 |
| DSPP | dentin sialophosphoprotein | 0.0223854 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0222144 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0219862 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.021629 |
| CTSB | cathepsin B | 0.0213553 |
| HOMER1 | homer scaffolding protein 1 | 0.021195 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.021121 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0208161 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0207457 |
| COPA | coatomer protein complex, subunit alpha | 0.0203967 |
| LMO7 | LIM domain 7 | 0.020363 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0202018 |
| ABR | active BCR-related | 0.0198744 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0198488 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0196611 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0196188 |
| FAT1 | FAT atypical cadherin 1 | 0.0194956 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0193033 |
| ARRDC3 | arrestin domain containing 3 | 0.0190959 |
| TPM3 | tropomyosin 3 | 0.0184217 |
| GOLGA4 | golgin A4 | 0.0182768 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0182203 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0181772 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0181096 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0179282 |
| VMP1 | vacuole membrane protein 1 | 0.0178924 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0177605 |
| NUP58 | nucleoporin 58 | 0.0177565 |
| SERTAD2 | SERTA domain containing 2 | 0.0176136 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0175127 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0175121 |
| CLDND1 | claudin domain containing 1 | 0.0174514 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0172493 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0170463 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0169645 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0168057 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0167376 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0164032 |
| FAM107B | family with sequence similarity 107, member B | 0.0163348 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.199065 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.181581 |
| PTMA | prothymosin, alpha | -0.143005 |
| FERMT1 | fermitin family member 1 | -0.113832 |
| TMSB10 | thymosin beta 10 | -0.0952421 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0885965 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0733497 |
| RAD51B | RAD51 paralog B | -0.0718643 |
| RPS24 | ribosomal protein S24 | -0.0713619 |
| FHIT | fragile histidine triad | -0.0696339 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.061962 |
| HDAC2 | histone deacetylase 2 | -0.0602421 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0588111 |
| OXR1 | oxidation resistance 1 | -0.0532059 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0506393 |
| RBM25 | RNA binding motif protein 25 | -0.0457212 |
| SERINC5 | serine incorporator 5 | -0.0451523 |
| MTAP | methylthioadenosine phosphorylase | -0.0402492 |
| RPL35A | ribosomal protein L35a | -0.0401557 |
| RPS6 | ribosomal protein S6 | -0.0390496 |
| RPL32 | ribosomal protein L32 | -0.0388256 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0378389 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0376304 |
| RPL34 | ribosomal protein L34 | -0.0374111 |
| AOPEP | aminopeptidase O (putative) | -0.0362458 |
| PERP | PERP, TP53 apoptosis effector | -0.0359691 |
| CD9 | CD9 molecule | -0.0350664 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0349604 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0347013 |
| S100A10 | S100 calcium binding protein A10 | -0.0340294 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0338086 |
| S100A6 | S100 calcium binding protein A6 | -0.0334744 |
| CCND1 | cyclin D1 | -0.0320127 |
| RPLP1 | ribosomal protein, large, P1 | -0.0319063 |
| EZR | ezrin | -0.0314562 |
| GPHN | gephyrin | -0.0311574 |
| RPS19 | ribosomal protein S19 | -0.0297277 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0292973 |
| RPL12 | ribosomal protein L12 | -0.0278875 |
| BMP4 | bone morphogenetic protein 4 | -0.0271421 |
| RPS21 | ribosomal protein S21 | -0.0270928 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0269656 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.026477 |
| CBX3 | chromobox homolog 3 | -0.026364 |
| PHF14 | PHD finger protein 14 | -0.0257638 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0253959 |
| RPL11 | ribosomal protein L11 | -0.0252276 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0250649 |
| TUBB | tubulin, beta class I | -0.024965 |
| EHBP1 | EH domain binding protein 1 | -0.0248318 |
| KLK10 | kallikrein-related peptidase 10 | -0.024663 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0241158 |
| MKI67 | marker of proliferation Ki-67 | -0.024082 |
| FOSL1 | FOS-like antigen 1 | -0.0239839 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0239236 |
| HMGA2 | high mobility group AT-hook 2 | -0.0236051 |
| RPL8 | ribosomal protein L8 | -0.0235932 |
| NEK7 | NIMA-related kinase 7 | -0.0231513 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.023143 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0230976 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0230379 |
| CUX1 | cut-like homeobox 1 | -0.0227323 |
| KRT18 | keratin 18, type I | -0.0225973 |
| HMGA1 | high mobility group AT-hook 1 | -0.0225919 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0225651 |
| DIAPH2 | diaphanous-related formin 2 | -0.0224189 |
| RPL31 | ribosomal protein L31 | -0.0221911 |
| RPS23 | ribosomal protein S23 | -0.0215069 |
| SMYD3 | SET and MYND domain containing 3 | -0.0211163 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0207333 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.020709 |
| EGR1 | early growth response 1 | -0.0204878 |
| RPL19 | ribosomal protein L19 | -0.020301 |
| RPL9 | ribosomal protein L9 | -0.0202015 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0201439 |
| RPS5 | ribosomal protein S5 | -0.0199858 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0199369 |
| EXOC4 | exocyst complex component 4 | -0.0197548 |
| RPL23 | ribosomal protein L23 | -0.0193695 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.01868 |
| ITGB4 | integrin, beta 4 | -0.0186273 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0186266 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0186112 |
| FLOT1 | flotillin 1 | -0.0186072 |
| RPS14 | ribosomal protein S14 | -0.0185626 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0183672 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0183509 |
| LMNA | lamin A/C | -0.0181838 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0178632 |
| NFIA | nuclear factor I/A | -0.0178414 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0175012 |
| RUNX2 | runt-related transcription factor 2 | -0.0174325 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0173972 |
| ACTN4 | actinin, alpha 4 | -0.0171894 |
| BCL2L1 | BCL2-like 1 | -0.017184 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0171055 |
| THOC2 | THO complex 2 | -0.0170873 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0165844 |
| S100A11 | S100 calcium binding protein A11 | -0.0165699 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -0.0165485 |
