| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tubulin inhibitor 6 perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tubulin inhibitor 6_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.170082 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.134934 |
| ACTG1 | actin gamma 1 | 0.134514 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.118332 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.118052 |
| VCL | vinculin | 0.112762 |
| ASPH | aspartate beta-hydroxylase | 0.110452 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0933365 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0833813 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0829396 |
| ENO1 | enolase 1, (alpha) | 0.0802452 |
| KRT8 | keratin 8, type II | 0.0784104 |
| AHNAK | AHNAK nucleoprotein | 0.0757505 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0731628 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0685004 |
| SDC4 | syndecan 4 | 0.0682655 |
| TNS3 | tensin 3 | 0.0659713 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0617788 |
| PCBP2 | poly(rC) binding protein 2 | 0.0611471 |
| LDHA | lactate dehydrogenase A | 0.0610176 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0605202 |
| YAP1 | Yes-associated protein 1 | 0.0599508 |
| POTEF | POTE ankyrin domain family, member F | 0.0579838 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0534758 |
| RPS12 | ribosomal protein S12 | 0.0494363 |
| SMAD3 | SMAD family member 3 | 0.048512 |
| SERINC5 | serine incorporator 5 | 0.0472282 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0464906 |
| LMO7 | LIM domain 7 | 0.0452871 |
| UBAP2 | ubiquitin associated protein 2 | 0.0452777 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0451174 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0448931 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0441803 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0439237 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0433314 |
| SQSTM1 | sequestosome 1 | 0.0426858 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0424926 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0422153 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0421733 |
| DST | dystonin | 0.0419841 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0419608 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0418358 |
| MYOF | myoferlin | 0.0411375 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0404605 |
| WWOX | WW domain containing oxidoreductase | 0.039137 |
| RCOR1 | REST corepressor 1 | 0.0384898 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.038132 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0373593 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0366429 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0358789 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0354917 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.035134 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0347985 |
| RPL35A | ribosomal protein L35a | 0.034781 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0344097 |
| PMM2 | phosphomannomutase 2 | 0.0334416 |
| DSPP | dentin sialophosphoprotein | 0.0329616 |
| TPM3 | tropomyosin 3 | 0.0329486 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0323876 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0323631 |
| RPS8 | ribosomal protein S8 | 0.0322477 |
| MYO1E | myosin IE | 0.032163 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0321211 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0319495 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0312859 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0311407 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0310937 |
| PLEC | plectin | 0.0307991 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.030731 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0298315 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0297789 |
| CDK13 | cyclin-dependent kinase 13 | 0.0291683 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0291248 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0286405 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.02827 |
| BPTF | bromodomain PHD finger transcription factor | 0.0280959 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0279586 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0278117 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0277983 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0277873 |
| ANXA3 | annexin A3 | 0.0274624 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0273939 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0272543 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0272108 |
| SEPTIN9 | septin 9 | 0.0271709 |
| MED13 | mediator complex subunit 13 | 0.0269891 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0268638 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.026802 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.026673 |
| EGFR | epidermal growth factor receptor | 0.0266363 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0261019 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0259804 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0257828 |
| MT2A | metallothionein 2A | 0.025687 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0256826 |
| SIK3 | SIK family kinase 3 | 0.0252036 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0251012 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0250021 |
| GOLGB1 | golgin B1 | 0.0249883 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0249772 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.111405 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0990278 |
| MKI67 | marker of proliferation Ki-67 | -0.0947588 |
| OXR1 | oxidation resistance 1 | -0.0658199 |
| DIAPH3 | diaphanous-related formin 3 | -0.0619538 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0608022 |
| RBM39 | RNA binding motif protein 39 | -0.0606357 |
| ANLN | anillin, actin binding protein | -0.0587778 |
| RPS24 | ribosomal protein S24 | -0.0580015 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0575887 |
| PROX1 | prospero homeobox 1 | -0.0570382 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0567084 |
| CCND1 | cyclin D1 | -0.0554349 |
| THOC2 | THO complex 2 | -0.0544247 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0507175 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0485636 |
| HMGA1 | high mobility group AT-hook 1 | -0.0470731 |
| TXNIP | thioredoxin interacting protein | -0.0462861 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0439728 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0437785 |
| H1-0 | H1.0 linker histone | -0.0436386 |
| PTMA | prothymosin, alpha | -0.0434994 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0431014 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0424324 |
| CENPF | centromere protein F, 350/400kDa | -0.042235 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0421932 |
| RPS2 | ribosomal protein S2 | -0.0418849 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0418746 |
| NF1 | neurofibromin 1 | -0.0412989 |
| RPL32 | ribosomal protein L32 | -0.0412925 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0394588 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0387752 |
| XPO1 | exportin 1 | -0.0386785 |
| CDK8 | cyclin-dependent kinase 8 | -0.0378262 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0378115 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0377596 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0376838 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0375971 |
| SNX9 | sorting nexin 9 | -0.0374593 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.037435 |
| MATR3 | matrin 3 | -0.0369582 |
| ABLIM1 | actin binding LIM protein 1 | -0.0365628 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0363857 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0362345 |
| SBF2 | SET binding factor 2 | -0.0353931 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0353807 |
| ZNF292 | zinc finger protein 292 | -0.0348762 |
| TUBB | tubulin, beta class I | -0.0347787 |
| EGR1 | early growth response 1 | -0.0345524 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0343749 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0343138 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0342327 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0341389 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0339604 |
| PERP | PERP, TP53 apoptosis effector | -0.0338203 |
| VGLL4 | vestigial-like family member 4 | -0.0336992 |
| R3HDM1 | R3H domain containing 1 | -0.0333541 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0330129 |
| H1-4 | H1.4 linker histone, cluster member | -0.0328334 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0327463 |
| YEATS2 | YEATS domain containing 2 | -0.0324144 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0320789 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0319681 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0317516 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0315788 |
| USP3 | ubiquitin specific peptidase 3 | -0.0314842 |
| RPS23 | ribosomal protein S23 | -0.031358 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0313226 |
| AOPEP | aminopeptidase O (putative) | -0.0308784 |
| UBAC2 | UBA domain containing 2 | -0.0307868 |
| RPL6 | ribosomal protein L6 | -0.0304506 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0302491 |
| NOP58 | NOP58 ribonucleoprotein | -0.0301997 |
| RPL38 | ribosomal protein L38 | -0.0300574 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0297725 |
| TPX2 | TPX2, microtubule-associated | -0.0296805 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.029476 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0294692 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0291782 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0290625 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0290247 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0289654 |
| CBX3 | chromobox homolog 3 | -0.0288295 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0282451 |
| KIF4A | kinesin family member 4A | -0.028171 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0281415 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.028078 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0277992 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0275859 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0274397 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0274352 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0272903 |
| RPS21 | ribosomal protein S21 | -0.0271734 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0270902 |
| SLX4IP | SLX4 interacting protein | -0.0270722 |
| RPS6 | ribosomal protein S6 | -0.0269073 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0269013 |
| RPL11 | ribosomal protein L11 | -0.0267001 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0265429 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0263035 |
