| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.113854 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0856403 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0754808 |
| NDRG1 | N-myc downstream regulated 1 | 0.07439 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0718929 |
| RUNX1 | runt-related transcription factor 1 | 0.0717846 |
| STC1 | stanniocalcin 1 | 0.0675428 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0669931 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0629993 |
| FLNB | filamin B, beta | 0.0585954 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.051741 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0499965 |
| EFNA5 | ephrin-A5 | 0.0459883 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0440109 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0421211 |
| POTEF | POTE ankyrin domain family, member F | 0.0411641 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0411617 |
| HDAC9 | histone deacetylase 9 | 0.0391901 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0389954 |
| CDH13 | cadherin 13 | 0.0386373 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0382968 |
| FAM107B | family with sequence similarity 107, member B | 0.0371479 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0370921 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0368927 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0360498 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0354558 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.034114 |
| MSN | moesin | 0.0338056 |
| PKM | pyruvate kinase, muscle | 0.0333244 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0317463 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0310454 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.030649 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0306263 |
| TPM3 | tropomyosin 3 | 0.030565 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0301862 |
| RPS6 | ribosomal protein S6 | 0.0300848 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.03006 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0293344 |
| FOSL1 | FOS-like antigen 1 | 0.0293035 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0292177 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0282304 |
| MYADM | myeloid-associated differentiation marker | 0.0282032 |
| RTN4 | reticulon 4 | 0.0281846 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0281004 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0277443 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0275709 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0270081 |
| VEGFA | vascular endothelial growth factor A | 0.0269507 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0269248 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.026864 |
| ENO1 | enolase 1, (alpha) | 0.0267897 |
| ITGA6 | integrin, alpha 6 | 0.026472 |
| RNF24 | ring finger protein 24 | 0.025929 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.025915 |
| TPM4 | tropomyosin 4 | 0.0256819 |
| PCBP2 | poly(rC) binding protein 2 | 0.0252033 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0250634 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0250542 |
| SMAD3 | SMAD family member 3 | 0.0249353 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0246725 |
| ZNF292 | zinc finger protein 292 | 0.0241313 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0238335 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0236259 |
| EZR | ezrin | 0.0235901 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0235681 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0232797 |
| DTNA | dystrobrevin, alpha | 0.023209 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0231663 |
| PRELID2 | PRELI domain containing 2 | 0.0226557 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0226324 |
| SETD5 | SET domain containing 5 | 0.0223075 |
| ERBIN | erbb2 interacting protein | 0.0223 |
| JUN | jun proto-oncogene | 0.0222622 |
| MYOF | myoferlin | 0.0222279 |
| RPLP1 | ribosomal protein, large, P1 | 0.0221853 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.021832 |
| PFKP | phosphofructokinase, platelet | 0.0213624 |
| SEPTIN9 | septin 9 | 0.0213377 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0212902 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0212121 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0211385 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.021037 |
| NABP1 | nucleic acid binding protein 1 | 0.0208138 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.020759 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0207331 |
| ADM | adrenomedullin | 0.0206981 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0206374 |
| XPO1 | exportin 1 | 0.0203095 |
| HELZ | helicase with zinc finger | 0.0202858 |
| SSH2 | slingshot protein phosphatase 2 | 0.0199987 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0199912 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.019985 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0199706 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0198951 |
| STXBP1 | syntaxin binding protein 1 | 0.0198609 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.019847 |
| RPL36 | ribosomal protein L36 | 0.0197429 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0196615 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0196295 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0195362 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | -0.173408 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.146255 |
| FBN1 | fibrillin 1 | -0.11371 |
| THBS2 | thrombospondin 2 | -0.0955546 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0807525 |
| PODXL | podocalyxin-like | -0.074529 |
| VIM | vimentin | -0.0743791 |
| COL3A1 | collagen, type III, alpha 1 | -0.0670372 |
| COL5A2 | collagen, type V, alpha 2 | -0.0608616 |
| MEIS2 | Meis homeobox 2 | -0.0587637 |
| PLAT | plasminogen activator, tissue | -0.0552403 |
| TMSB10 | thymosin beta 10 | -0.0522734 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0474713 |
| HLA-B | major histocompatibility complex, class I, B | -0.0473621 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0440579 |
| COL1A2 | collagen, type I, alpha 2 | -0.0430959 |
| S100A6 | S100 calcium binding protein A6 | -0.038293 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.038175 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0368082 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0350132 |
| MX2 | MX dynamin-like GTPase 2 | -0.0339736 |
| PRSS23 | protease, serine, 23 | -0.0331065 |
| NAV1 | neuron navigator 1 | -0.0320213 |
| CAVIN1 | caveolae associated protein 1 | -0.0317891 |
| HLA-E | major histocompatibility complex, class I, E | -0.0313839 |
| ANXA2 | annexin A2 | -0.0312412 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.028926 |
| EHBP1 | EH domain binding protein 1 | -0.0279272 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0279232 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0276793 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0272048 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0268597 |
| RAI14 | retinoic acid induced 14 | -0.0267815 |
| FRMD4A | FERM domain containing 4A | -0.0257515 |
| RIGI | RNA sensor RIG-I | -0.025386 |
| VEGFC | vascular endothelial growth factor C | -0.0253489 |
| KIFAP3 | kinesin-associated protein 3 | -0.0250271 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0249465 |
| HLA-C | major histocompatibility complex, class I, C | -0.0245261 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0245062 |
| AHNAK | AHNAK nucleoprotein | -0.0237116 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0236128 |
| S100A10 | S100 calcium binding protein A10 | -0.023562 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.023555 |
| TUBB | tubulin, beta class I | -0.0230981 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0229922 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0225163 |
| SUCNR1 | succinate receptor 1 | -0.0223707 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0223494 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0222543 |
| AUTS2 | autism susceptibility candidate 2 | -0.0221998 |
| TDRD7 | tudor domain containing 7 | -0.0218971 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0218204 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.021816 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0215152 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0213833 |
| GOLGA2 | golgin A2 | -0.0211585 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0210497 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0208738 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.020642 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0205674 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0205511 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0204854 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0203774 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0203118 |
| GLIS3 | GLIS family zinc finger 3 | -0.0201474 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0198172 |
| TNS3 | tensin 3 | -0.0193965 |
| TMSB4X | thymosin beta 4, X-linked | -0.0188158 |
| AOPEP | aminopeptidase O (putative) | -0.0183615 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0183192 |
| NEK7 | NIMA-related kinase 7 | -0.0182856 |
| RAD21 | RAD21 homolog (S. pombe) | -0.018263 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0180831 |
| CCND1 | cyclin D1 | -0.0178531 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0177617 |
| LOXL2 | lysyl oxidase-like 2 | -0.0173888 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0171235 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0170369 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0170073 |
| ATP13A3 | ATPase type 13A3 | -0.0169341 |
| CANX | calnexin | -0.0164206 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0163989 |
| PRRX1 | paired related homeobox 1 | -0.0161118 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0160903 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0158482 |
| UBQLN1 | ubiquilin 1 | -0.0156901 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0156093 |
| CEP350 | centrosomal protein 350kDa | -0.0155685 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0152479 |
| NPR2 | natriuretic peptide receptor 2 | -0.0151676 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0148634 |
| ABI1 | abl-interactor 1 | -0.014801 |
| CDK6 | cyclin-dependent kinase 6 | -0.0147657 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0147015 |
| CEP112 | centrosomal protein 112kDa | -0.0146735 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0145639 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.0145064 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0144569 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0144114 |
