| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.159421 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0784899 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0732124 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.07234 |
| PRKCA | protein kinase C, alpha | 0.0650181 |
| TLE4 | transducin-like enhancer of split 4 | 0.05497 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.054596 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0529046 |
| PLAT | plasminogen activator, tissue | 0.0463465 |
| VMP1 | vacuole membrane protein 1 | 0.0441995 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0431188 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0412994 |
| MCL1 | myeloid cell leukemia 1 | 0.0395131 |
| DPH6 | diphthamine biosynthesis 6 | 0.0394778 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0374333 |
| EGR1 | early growth response 1 | 0.035417 |
| LSAMP | limbic system-associated membrane protein | 0.0352337 |
| AHR | aryl hydrocarbon receptor | 0.0338361 |
| FN1 | fibronectin 1 | 0.0336633 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0330192 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0308112 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0307246 |
| NDRG1 | N-myc downstream regulated 1 | 0.0307052 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0300559 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0290891 |
| STC1 | stanniocalcin 1 | 0.0287446 |
| FERMT2 | fermitin family member 2 | 0.0276326 |
| VEGFA | vascular endothelial growth factor A | 0.0275142 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.026663 |
| DST | dystonin | 0.0266355 |
| NREP | neuronal regeneration related protein | 0.0257518 |
| RPS12 | ribosomal protein S12 | 0.0256395 |
| FHIT | fragile histidine triad | 0.0242559 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0242213 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0237055 |
| CRH | corticotropin releasing hormone | 0.0236249 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0233877 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0233809 |
| TPM1 | tropomyosin 1 (alpha) | 0.0233743 |
| ASPH | aspartate beta-hydroxylase | 0.0232157 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.023082 |
| DIAPH2 | diaphanous-related formin 2 | 0.0227678 |
| ATXN1 | ataxin 1 | 0.022571 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0224005 |
| MYO1E | myosin IE | 0.0221487 |
| HOMER1 | homer scaffolding protein 1 | 0.0221309 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0220647 |
| INTS6 | integrator complex subunit 6 | 0.0218623 |
| IER3 | immediate early response 3 | 0.0216637 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0216412 |
| CDH13 | cadherin 13 | 0.021579 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0214957 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0212338 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0211787 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0209689 |
| AEBP2 | AE binding protein 2 | 0.0206372 |
| TXNIP | thioredoxin interacting protein | 0.0202904 |
| DACH2 | dachshund family transcription factor 2 | 0.0202889 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | 0.019992 |
| ZNF638 | zinc finger protein 638 | 0.0199284 |
| PALLD | palladin, cytoskeletal associated protein | 0.0195854 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0194452 |
| MRTFA | myocardin related transcription factor A | 0.0192685 |
| PCDH15 | protocadherin-related 15 | 0.01917 |
| GSE1 | Gse1 coiled-coil protein | 0.0190611 |
| SNX14 | sorting nexin 14 | 0.0189118 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0187644 |
| RAD51B | RAD51 paralog B | 0.0185769 |
| BRD2 | bromodomain containing 2 | 0.018324 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0182874 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0182635 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0182214 |
| ANGPTL4 | angiopoietin-like 4 | 0.0180455 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0179623 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0179521 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0173245 |
| STK38L | serine/threonine kinase 38 like | 0.0170485 |
| KCNIP4 | Kv channel interacting protein 4 | 0.01701 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0169134 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.016662 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.0165722 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0164922 |
| SETBP1 | SET binding protein 1 | 0.016457 |
| NAV1 | neuron navigator 1 | 0.0161768 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0161647 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0160557 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0159601 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0159543 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0158789 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0158379 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0157827 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0155192 |
| UBC | ubiquitin C | 0.0152998 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0152599 |
| RPL37A | ribosomal protein L37a | 0.0152576 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0152293 |
| SYTL3 | synaptotagmin-like 3 | 0.0151915 |
| GOLGB1 | golgin B1 | 0.01514 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0151156 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0150803 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.391963 |
| IGF2 | insulin-like growth factor 2 | -0.245503 |
| PTMA | prothymosin, alpha | -0.0717308 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.058277 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0582094 |
| COL3A1 | collagen, type III, alpha 1 | -0.0577446 |
| VIM | vimentin | -0.0497071 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0491915 |
| FMN1 | formin 1 | -0.046763 |
| SYT1 | synaptotagmin I | -0.0465371 |
| LPIN1 | lipin 1 | -0.0459815 |
| SPAG9 | sperm associated antigen 9 | -0.0439483 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0433068 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0426581 |
| KLHL13 | kelch-like family member 13 | -0.0420087 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0397773 |
| TRIB2 | tribbles pseudokinase 2 | -0.0392494 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0390035 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0384065 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0381719 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0361053 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0345865 |
| TMSB10 | thymosin beta 10 | -0.0344723 |
| RBM25 | RNA binding motif protein 25 | -0.0340681 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0337938 |
| NRG1 | neuregulin 1 | -0.0325863 |
| AOPEP | aminopeptidase O (putative) | -0.0325705 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0317004 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0315729 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0315528 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0313577 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0311899 |
| HMGB2 | high mobility group box 2 | -0.0301996 |
| RPL38 | ribosomal protein L38 | -0.0299032 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0296158 |
| WDR45B | WD repeat domain 45B | -0.0295766 |
| SP100 | SP100 nuclear antigen | -0.0295758 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294699 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0287697 |
| HELZ | helicase with zinc finger | -0.0287678 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.028767 |
| MAP1B | microtubule-associated protein 1B | -0.0283913 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0275164 |
| RPL35A | ribosomal protein L35a | -0.0274045 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0268161 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0267277 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0264832 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0264304 |
| OGA | O-GlcNAcase | -0.0262923 |
| RPL19 | ribosomal protein L19 | -0.0259481 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0259034 |
| TMEM123 | transmembrane protein 123 | -0.0256657 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0255211 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0255192 |
| NRP1 | neuropilin 1 | -0.0251667 |
| NEK7 | NIMA-related kinase 7 | -0.0251472 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0250532 |
| RPS24 | ribosomal protein S24 | -0.0250145 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0250005 |
| B2M | beta-2-microglobulin | -0.02457 |
| H3-3B | H3.3 histone B | -0.0244435 |
| CCND1 | cyclin D1 | -0.0243675 |
| GNAS | GNAS complex locus | -0.0238143 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0237386 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0236677 |
| RPL26 | ribosomal protein L26 | -0.0235817 |
| MSI2 | musashi RNA-binding protein 2 | -0.0233738 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0232065 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0229637 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0228908 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.022843 |
| TLK2 | tousled-like kinase 2 | -0.0227486 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0224993 |
| FTL | ferritin, light polypeptide | -0.0221971 |
| FOXK2 | forkhead box K2 | -0.0221331 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0221265 |
| GOLGA4 | golgin A4 | -0.0220718 |
| QKI | QKI, KH domain containing, RNA binding | -0.0220681 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0219897 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0218874 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0217947 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0214961 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0214691 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0214036 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0212761 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0210593 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.020686 |
| ZNF804A | zinc finger protein 804A | -0.0206593 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0205583 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0204059 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0203502 |
| USP3 | ubiquitin specific peptidase 3 | -0.0201816 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0201626 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0200651 |
| CLTC | clathrin, heavy chain (Hc) | -0.0200252 |
| CCDC47 | coiled-coil domain containing 47 | -0.020025 |
| CCNI | cyclin I | -0.01965 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0196465 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0195794 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0194351 |
