| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RUNX1 | runt-related transcription factor 1 | 0.041707 |
| RNF43 | ring finger protein 43 | 0.0334316 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0326023 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0311113 |
| SMAD3 | SMAD family member 3 | 0.0305464 |
| LMO7 | LIM domain 7 | 0.0253218 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.022329 |
| IFNGR1 | interferon gamma receptor 1 | 0.0220424 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0206032 |
| ATP10B | ATPase, class V, type 10B | 0.0197659 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0196044 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.01762 |
| XDH | xanthine dehydrogenase | 0.0170825 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0169211 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0163081 |
| YAP1 | Yes-associated protein 1 | 0.0162841 |
| AOPEP | aminopeptidase O (putative) | 0.0161324 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0153657 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0145214 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0143497 |
| ETNK1 | ethanolamine kinase 1 | 0.0142076 |
| TC2N | tandem C2 domains, nuclear | 0.0141063 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0140992 |
| PTEN | phosphatase and tensin homolog | 0.0138296 |
| EHF | ets homologous factor | 0.0136844 |
| DIAPH3 | diaphanous-related formin 3 | 0.0135226 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0135169 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0130562 |
| DUSP16 | dual specificity phosphatase 16 | 0.0130285 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0129171 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0128049 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0126917 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0126807 |
| DHFR | dihydrofolate reductase | 0.0126326 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0125987 |
| MECOM | MDS1 and EVI1 complex locus | 0.0124303 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0119987 |
| DST | dystonin | 0.0119907 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0119409 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.011936 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0118987 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0117927 |
| ZNRF3 | zinc and ring finger 3 | 0.0116649 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0115978 |
| PRSS22 | protease, serine, 22 | 0.0112976 |
| RREB1 | ras responsive element binding protein 1 | 0.0111821 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0111029 |
| CENPF | centromere protein F, 350/400kDa | 0.0107917 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.010627 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0106128 |
| TMEM39A | transmembrane protein 39A | 0.0104699 |
| TRIM2 | tripartite motif containing 2 | 0.0104406 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0104369 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0104274 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0103393 |
| CD58 | CD58 molecule | 0.0102619 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0101598 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0100941 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00976424 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.00927454 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00925118 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.00912447 |
| ZNF638 | zinc finger protein 638 | 0.0091217 |
| TOX3 | TOX high mobility group box family member 3 | 0.00907825 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00902152 |
| CORO1C | coronin, actin binding protein, 1C | 0.00894204 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00892905 |
| FOSL2 | FOS-like antigen 2 | 0.00892663 |
| WWOX | WW domain containing oxidoreductase | 0.00890345 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.00886948 |
| TNRC6A | trinucleotide repeat containing 6A | 0.00881943 |
| AHR | aryl hydrocarbon receptor | 0.00881905 |
| MKI67 | marker of proliferation Ki-67 | 0.00874705 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00874244 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00873175 |
| EREG | epiregulin | 0.00873057 |
| FER | fer (fps/fes related) tyrosine kinase | 0.00871358 |
| EXOC6B | exocyst complex component 6B | 0.00867451 |
| MYO1B | myosin IB | 0.00866456 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00865256 |
| FLNB | filamin B, beta | 0.00864741 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.00860504 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00859423 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00856315 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00854052 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00847459 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0083727 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | 0.00833697 |
| GRAMD2B | GRAM domain containing 2B | 0.00831605 |
| TMEM45B | transmembrane protein 45B | 0.00830797 |
| SH3PXD2A | SH3 and PX domains 2A | 0.00828972 |
| RTN4 | reticulon 4 | 0.00824446 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.00811988 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.00810789 |
| XPO1 | exportin 1 | 0.00809418 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00808768 |
| YTHDC1 | YTH domain containing 1 | 0.00794504 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0078989 |
| ZNF608 | zinc finger protein 608 | 0.00787601 |
| CCDC14 | coiled-coil domain containing 14 | 0.00786659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.204185 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.128802 |
| B2M | beta-2-microglobulin | -0.121597 |
| INTS6 | integrator complex subunit 6 | -0.11827 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.11677 |
| HLA-B | major histocompatibility complex, class I, B | -0.0915372 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0902556 |
| RNF213 | ring finger protein 213 | -0.0901164 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0889609 |
| PTMA | prothymosin, alpha | -0.0872929 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0822438 |
| ANXA2 | annexin A2 | -0.0821439 |
| LYZ | lysozyme | -0.0807779 |
| EGR1 | early growth response 1 | -0.0794927 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0786405 |
| SP100 | SP100 nuclear antigen | -0.0768531 |
| RIGI | RNA sensor RIG-I | -0.0763725 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0742662 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0734591 |
| PERP | PERP, TP53 apoptosis effector | -0.0688397 |
| XAF1 | XIAP associated factor 1 | -0.0682414 |
| SQSTM1 | sequestosome 1 | -0.0682023 |
| PLSCR2 | phospholipid scramblase 2 | -0.0673482 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0671676 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0671201 |
| NPSR1 | neuropeptide S receptor 1 | -0.0635948 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0627758 |
| PKM | pyruvate kinase, muscle | -0.0626379 |
| VCL | vinculin | -0.0624811 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0620258 |
| MUC20 | mucin 20, cell surface associated | -0.0606929 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0584053 |
| PHF3 | PHD finger protein 3 | -0.0573982 |
| EZR | ezrin | -0.0564593 |
| PLSCR1 | phospholipid scramblase 1 | -0.056321 |
| MX1 | MX dynamin-like GTPase 1 | -0.0562433 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0561755 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0551132 |
| MAP7 | microtubule-associated protein 7 | -0.0545523 |
| HLA-E | major histocompatibility complex, class I, E | -0.0543569 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0527977 |
| AHI1 | Abelson helper integration site 1 | -0.0516247 |
| MX2 | MX dynamin-like GTPase 2 | -0.0516242 |
| GOLGB1 | golgin B1 | -0.0502267 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.049101 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0485505 |
| PGK1 | phosphoglycerate kinase 1 | -0.0476526 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0472977 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0460038 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0456821 |
| FTL | ferritin, light polypeptide | -0.0455924 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0455054 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.044648 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0444966 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0444771 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0444672 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0440804 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0437832 |
| LCN2 | lipocalin 2 | -0.0435032 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0429134 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0426244 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0423606 |
| EPCAM | epithelial cell adhesion molecule | -0.0422887 |
| HLA-C | major histocompatibility complex, class I, C | -0.0416432 |
| MCL1 | myeloid cell leukemia 1 | -0.040887 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0404521 |
| RPL35A | ribosomal protein L35a | -0.0404054 |
| AREG | amphiregulin | -0.0401769 |
| CANX | calnexin | -0.0401102 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0397073 |
| NCKAP5 | NCK-associated protein 5 | -0.0395693 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0394621 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0394298 |
| TMSB10 | thymosin beta 10 | -0.039167 |
| TXNIP | thioredoxin interacting protein | -0.0390002 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0388452 |
| ACTG1 | actin gamma 1 | -0.038828 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0387656 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0385032 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0382636 |
| POU2F2 | POU class 2 homeobox 2 | -0.0380803 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0375948 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0375143 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0374481 |
| PMP22 | peripheral myelin protein 22 | -0.0369373 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0363756 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0361645 |
| PRKCA | protein kinase C, alpha | -0.0361196 |
| UBC | ubiquitin C | -0.0359101 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0358428 |
| RPL34 | ribosomal protein L34 | -0.0358357 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0355872 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0355752 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0354528 |
| ZNF292 | zinc finger protein 292 | -0.0343858 |
| RAD51B | RAD51 paralog B | -0.0343395 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.034214 |
| ARF1 | ADP-ribosylation factor 1 | -0.0335238 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0331137 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0330679 |
