| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.240749 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.220349 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.117973 |
| COL1A2 | collagen, type I, alpha 2 | 0.0993179 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0674625 |
| FN1 | fibronectin 1 | 0.0625732 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0589437 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0488538 |
| SDC2 | syndecan 2 | 0.0431965 |
| VIM | vimentin | 0.0427631 |
| STC1 | stanniocalcin 1 | 0.0417286 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0401916 |
| ATP13A3 | ATPase type 13A3 | 0.0391038 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0375768 |
| IL6 | interleukin 6 | 0.0375568 |
| TPM4 | tropomyosin 4 | 0.0362271 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0356011 |
| HAS2 | hyaluronan synthase 2 | 0.0349489 |
| VCAN | versican | 0.034633 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0340971 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0338851 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0302932 |
| OSMR | oncostatin M receptor | 0.0301604 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0272061 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.027109 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0265539 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0255629 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0242362 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0241704 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.023501 |
| MMP3 | matrix metallopeptidase 3 | 0.0230789 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0230641 |
| PRRX1 | paired related homeobox 1 | 0.0227074 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0226216 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0220924 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.021952 |
| CLMP | CXADR-like membrane protein | 0.02194 |
| VEGFA | vascular endothelial growth factor A | 0.02159 |
| CD44 | CD44 molecule (Indian blood group) | 0.0210451 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.02039 |
| AXL | AXL receptor tyrosine kinase | 0.0200105 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0198908 |
| SVIL | supervillin | 0.0196848 |
| DUSP6 | dual specificity phosphatase 6 | 0.0192986 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0191653 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0189895 |
| NOTCH2 | notch 2 | 0.0189367 |
| NRP1 | neuropilin 1 | 0.0189007 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0186849 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0184939 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0183562 |
| HMGA2 | high mobility group AT-hook 2 | 0.0178969 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0178196 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0176667 |
| MYO1B | myosin IB | 0.0173893 |
| HLA-A | major histocompatibility complex, class I, A | 0.0171975 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0171596 |
| MYO10 | myosin X | 0.016823 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0166251 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0166236 |
| POSTN | periostin, osteoblast specific factor | 0.0163123 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0161668 |
| TMEM165 | transmembrane protein 165 | 0.0161122 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0159215 |
| JAG1 | jagged 1 | 0.0156827 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0156628 |
| VEGFC | vascular endothelial growth factor C | 0.015559 |
| COL3A1 | collagen, type III, alpha 1 | 0.0155512 |
| LAMB1 | laminin, beta 1 | 0.0155164 |
| FAT1 | FAT atypical cadherin 1 | 0.0154022 |
| HLTF | helicase-like transcription factor | 0.0151501 |
| IL1R1 | interleukin 1 receptor, type I | 0.0151102 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0148106 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0146155 |
| CD59 | CD59 molecule, complement regulatory protein | 0.01444 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.014066 |
| CCND1 | cyclin D1 | 0.0140597 |
| ZNF385D | zinc finger protein 385D | 0.0140044 |
| FRMD6 | FERM domain containing 6 | 0.0137115 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0135846 |
| SFTPA2 | surfactant protein A2 | 0.0135491 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.0135323 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | 0.0133852 |
| RYBP | RING1 and YY1 binding protein | 0.0132765 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0131065 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0129353 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0129206 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0128401 |
| MCC | mutated in colorectal cancers | 0.0126117 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0125726 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0125503 |
| TPM3 | tropomyosin 3 | 0.0125406 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0125305 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.01251 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0123929 |
| MYADM | myeloid-associated differentiation marker | 0.0123909 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0122877 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | 0.0121275 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0119835 |
| SKIL | SKI-like proto-oncogene | 0.0117697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | -0.160036 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.155652 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.144328 |
| EXT1 | exostosin glycosyltransferase 1 | -0.132023 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128112 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.123773 |
| MT2A | metallothionein 2A | -0.107514 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.095935 |
| CADM1 | cell adhesion molecule 1 | -0.0923868 |
| PRELID2 | PRELI domain containing 2 | -0.0875243 |
| NDRG1 | N-myc downstream regulated 1 | -0.0837714 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0834356 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0778582 |
| TMSB10 | thymosin beta 10 | -0.0748377 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0706194 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0679725 |
| COL5A1 | collagen, type V, alpha 1 | -0.0655459 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0653639 |
| SMYD3 | SET and MYND domain containing 3 | -0.0650521 |
| PDE10A | phosphodiesterase 10A | -0.0633356 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0601657 |
| ACTG1 | actin gamma 1 | -0.0598347 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0598232 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0595026 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0556735 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.054755 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0546876 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0538948 |
| BBX | bobby sox homolog (Drosophila) | -0.0533717 |
| GOLGB1 | golgin B1 | -0.0530467 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0509632 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0508399 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0505927 |
| SQSTM1 | sequestosome 1 | -0.0500973 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0496791 |
| ASPH | aspartate beta-hydroxylase | -0.0488226 |
| EGFR | epidermal growth factor receptor | -0.0473438 |
| CLIC4 | chloride intracellular channel 4 | -0.0472847 |
| CANX | calnexin | -0.0455936 |
| FTL | ferritin, light polypeptide | -0.0445492 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0444776 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0439317 |
| GOLGA4 | golgin A4 | -0.0437417 |
| MT1X | metallothionein 1X | -0.0435495 |
| RRBP1 | ribosome binding protein 1 | -0.0434115 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0419346 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0418094 |
| FBN1 | fibrillin 1 | -0.0408184 |
| COG5 | component of oligomeric golgi complex 5 | -0.0399687 |
| RNF220 | ring finger protein 220 | -0.0399052 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0390652 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0388139 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0383739 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0382458 |
| IER3 | immediate early response 3 | -0.0381303 |
| MAP4 | microtubule-associated protein 4 | -0.0373181 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | -0.0366933 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0358992 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0356288 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0355985 |
| HDAC9 | histone deacetylase 9 | -0.035509 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0354016 |
| DST | dystonin | -0.0351528 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0349127 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0346878 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0346696 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0343297 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0339261 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.033709 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0335212 |
| BNC2 | basonuclin 2 | -0.0331242 |
| RPL35A | ribosomal protein L35a | -0.0330337 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.032757 |
| CDK13 | cyclin-dependent kinase 13 | -0.0325931 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0324581 |
| ARF4 | ADP-ribosylation factor 4 | -0.0320632 |
| LOXL2 | lysyl oxidase-like 2 | -0.0320067 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0319278 |
| EXOC4 | exocyst complex component 4 | -0.0317291 |
| RIGI | RNA sensor RIG-I | -0.0316543 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0311806 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0311641 |
| FRMD4A | FERM domain containing 4A | -0.0310371 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0310173 |
| RPS8 | ribosomal protein S8 | -0.0308836 |
| NAV2 | neuron navigator 2 | -0.0308669 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0305639 |
| EPHB1 | EPH receptor B1 | -0.0301706 |
| PLEC | plectin | -0.0299903 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0298961 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0298177 |
| VCL | vinculin | -0.0296829 |
| RPS19 | ribosomal protein S19 | -0.0294763 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0292712 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0286754 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0285145 |
| CMIP | c-Maf inducing protein | -0.0284756 |
| CENPF | centromere protein F, 350/400kDa | -0.0284283 |
| MTDH | metadherin | -0.0281799 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0280115 |
