| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.244134 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.151435 |
| LMO7 | LIM domain 7 | 0.123757 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.114497 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.105703 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0967004 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0962807 |
| PDLIM5 | PDZ and LIM domain 5 | 0.08275 |
| MTSS1 | metastasis suppressor 1 | 0.0602174 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.060201 |
| HMGA2 | high mobility group AT-hook 2 | 0.0561645 |
| AHNAK | AHNAK nucleoprotein | 0.0549505 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0531239 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.052375 |
| INTS6 | integrator complex subunit 6 | 0.0521572 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0510797 |
| RASAL2 | RAS protein activator like 2 | 0.0504341 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0489593 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0488715 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0475103 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0469743 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0462057 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0460742 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0460476 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0453256 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.042854 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0408562 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.04039 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0400182 |
| RNF217 | ring finger protein 217 | 0.0387457 |
| PALLD | palladin, cytoskeletal associated protein | 0.0379292 |
| MECOM | MDS1 and EVI1 complex locus | 0.0366418 |
| SULF2 | sulfatase 2 | 0.0361682 |
| RIGI | RNA sensor RIG-I | 0.0336007 |
| LAMC2 | laminin, gamma 2 | 0.0335622 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0320325 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0308944 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0308238 |
| RAD51B | RAD51 paralog B | 0.0306996 |
| HDAC9 | histone deacetylase 9 | 0.0305282 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0295236 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0291309 |
| PRSS23 | protease, serine, 23 | 0.0290651 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0285835 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.02826 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0282481 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0280069 |
| MTAP | methylthioadenosine phosphorylase | 0.0274721 |
| AMOTL1 | angiomotin like 1 | 0.0258184 |
| TNS3 | tensin 3 | 0.025537 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0249101 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0248205 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0244691 |
| KIAA1671 | KIAA1671 | 0.0244496 |
| EFNA5 | ephrin-A5 | 0.0244135 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0244072 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0243489 |
| UTRN | utrophin | 0.0242233 |
| RCOR1 | REST corepressor 1 | 0.0237542 |
| SMYD3 | SET and MYND domain containing 3 | 0.0236742 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0234262 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0233467 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0231722 |
| PLS3 | plastin 3 | 0.0231142 |
| EGFR | epidermal growth factor receptor | 0.0228149 |
| CALB1 | calbindin 1, 28kDa | 0.022642 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0225568 |
| DST | dystonin | 0.0225349 |
| JMJD1C | jumonji domain containing 1C | 0.0224396 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0221884 |
| DGKH | diacylglycerol kinase, eta | 0.0213634 |
| PLXNA2 | plexin A2 | 0.0211032 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0210561 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0207252 |
| EXOC4 | exocyst complex component 4 | 0.0206863 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0203696 |
| TENM4 | teneurin transmembrane protein 4 | 0.0199176 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0198379 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0195253 |
| CUX1 | cut-like homeobox 1 | 0.019321 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0193024 |
| CTBP2 | C-terminal binding protein 2 | 0.0192271 |
| FRMD4B | FERM domain containing 4B | 0.0190005 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0188507 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0185792 |
| IFI44L | interferon-induced protein 44-like | 0.0183394 |
| CDK6 | cyclin-dependent kinase 6 | 0.0181392 |
| SVIL | supervillin | 0.0179931 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0179473 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.017595 |
| SIK3 | SIK family kinase 3 | 0.0172905 |
| DOK5 | docking protein 5 | 0.0171881 |
| CRACDL | CRACD like | 0.017163 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0169151 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0168357 |
| CNTNAP3 | contactin associated protein-like 3 | 0.0167984 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0167625 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0166787 |
| LAMA4 | laminin, alpha 4 | 0.0166778 |
| PODXL | podocalyxin-like | 0.0166765 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | -0.137399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.136513 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.105912 |
| NDRG1 | N-myc downstream regulated 1 | -0.104572 |
| MEF2A | myocyte enhancer factor 2A | -0.0727646 |
| MT2A | metallothionein 2A | -0.0708831 |
| B2M | beta-2-microglobulin | -0.0662145 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0661002 |
| CUL4B | cullin 4B | -0.0642987 |
| GOLGA4 | golgin A4 | -0.0632354 |
| RPS21 | ribosomal protein S21 | -0.0611797 |
| PTMA | prothymosin, alpha | -0.0596643 |
| TMSB10 | thymosin beta 10 | -0.0583555 |
| RBM39 | RNA binding motif protein 39 | -0.0560538 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0558304 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0546722 |
| PLAT | plasminogen activator, tissue | -0.0543216 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0529565 |
| DSTN | destrin (actin depolymerizing factor) | -0.0518855 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0518674 |
| ANLN | anillin, actin binding protein | -0.0515884 |
| PGK1 | phosphoglycerate kinase 1 | -0.0512966 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0489833 |
| FLNB | filamin B, beta | -0.0485165 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0481631 |
| MYOF | myoferlin | -0.0473314 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0467414 |
| KRT17 | keratin 17, type I | -0.0450582 |
| ARRDC3 | arrestin domain containing 3 | -0.0448475 |
| RPS2 | ribosomal protein S2 | -0.0442847 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0437579 |
| ENO1 | enolase 1, (alpha) | -0.0428734 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0426621 |
| LMNA | lamin A/C | -0.0422317 |
| TMSB4X | thymosin beta 4, X-linked | -0.0416505 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0415168 |
| RPLP2 | ribosomal protein, large, P2 | -0.0413336 |
| LDHA | lactate dehydrogenase A | -0.040801 |
| CANX | calnexin | -0.0404866 |
| RPS6 | ribosomal protein S6 | -0.0403206 |
| POTEF | POTE ankyrin domain family, member F | -0.0400273 |
| BCL2L1 | BCL2-like 1 | -0.0398725 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0387131 |
| SERINC3 | serine incorporator 3 | -0.0386773 |
| RPS13 | ribosomal protein S13 | -0.0382413 |
| S100A10 | S100 calcium binding protein A10 | -0.0377943 |
| OGA | O-GlcNAcase | -0.0375539 |
| RPL11 | ribosomal protein L11 | -0.0374301 |
| RPS3 | ribosomal protein S3 | -0.037368 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0369792 |
| IGF2 | insulin-like growth factor 2 | -0.0368099 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0365066 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0363185 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0354055 |
| PKM | pyruvate kinase, muscle | -0.0348163 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0343552 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.034277 |
| COG5 | component of oligomeric golgi complex 5 | -0.0340537 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0338443 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0336414 |
| ZNF292 | zinc finger protein 292 | -0.0331963 |
| ITGA6 | integrin, alpha 6 | -0.0321946 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0320286 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0319341 |
| TPX2 | TPX2, microtubule-associated | -0.0316229 |
| SUCO | SUN domain containing ossification factor | -0.0316147 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0307965 |
| GNAS | GNAS complex locus | -0.0306857 |
| RIN2 | Ras and Rab interactor 2 | -0.0306174 |
| YBX3 | Y box binding protein 3 | -0.030563 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0305196 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0304327 |
| RPS8 | ribosomal protein S8 | -0.0303876 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0299136 |
| EFHD2 | EF-hand domain family, member D2 | -0.0297742 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0293281 |
| RPL7 | ribosomal protein L7 | -0.0290797 |
| SRP54 | signal recognition particle 54kDa | -0.0287819 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0286183 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0286093 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0283489 |
| PDLIM1 | PDZ and LIM domain 1 | -0.0282207 |
| RPS12 | ribosomal protein S12 | -0.0280922 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0280348 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0280321 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0278028 |
| ANXA2 | annexin A2 | -0.0277509 |
| CD99 | CD99 molecule | -0.0277043 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0274929 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0272952 |
| WASF2 | WAS protein family, member 2 | -0.0270486 |
| RPS19 | ribosomal protein S19 | -0.0268334 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0267673 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0266946 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0266455 |
| S100A2 | S100 calcium binding protein A2 | -0.0265791 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0264703 |
| YBX1 | Y box binding protein 1 | -0.0263231 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0259996 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0259414 |