| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.0702855 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0484856 |
| LMO7 | LIM domain 7 | 0.0469707 |
| VCL | vinculin | 0.0397583 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0374513 |
| NDRG1 | N-myc downstream regulated 1 | 0.0312051 |
| MYO1E | myosin IE | 0.0302479 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0292444 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0283443 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0271111 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0270528 |
| EGR1 | early growth response 1 | 0.0236378 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0234697 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0230034 |
| LAMA4 | laminin, alpha 4 | 0.0203234 |
| USP53 | ubiquitin specific peptidase 53 | 0.0198798 |
| INTS6 | integrator complex subunit 6 | 0.0193536 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.018976 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0189568 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0188281 |
| POF1B | premature ovarian failure, 1B | 0.0177056 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0175025 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0171293 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0170053 |
| EFNB2 | ephrin-B2 | 0.016643 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0165648 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0158163 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0155687 |
| CLDN4 | claudin 4 | 0.0151107 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0145943 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0143193 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0139184 |
| PALLD | palladin, cytoskeletal associated protein | 0.0136429 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0136213 |
| MUC13 | mucin 13, cell surface associated | 0.0132119 |
| NABP1 | nucleic acid binding protein 1 | 0.0131532 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0130662 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0130245 |
| TMC5 | transmembrane channel-like 5 | 0.0128929 |
| FRY | furry homolog (Drosophila) | 0.0127361 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0127027 |
| GDA | guanine deaminase | 0.0125967 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0124657 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0121549 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.01214 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0121301 |
| CAPRIN2 | caprin family member 2 | 0.0116926 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0111843 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0111225 |
| TRIB1 | tribbles pseudokinase 1 | 0.0109794 |
| ATP10B | ATPase, class V, type 10B | 0.0107161 |
| SGMS2 | sphingomyelin synthase 2 | 0.0102001 |
| TUFT1 | tuftelin 1 | 0.0101382 |
| XDH | xanthine dehydrogenase | 0.00999943 |
| DUSP16 | dual specificity phosphatase 16 | 0.00999689 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00993394 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00983519 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.00977433 |
| EFNA5 | ephrin-A5 | 0.00973049 |
| TMEM45B | transmembrane protein 45B | 0.00947744 |
| FBXW10B | F-box and WD repeat domain containing 10B | 0.00942244 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.00932228 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.00930334 |
| SMAD3 | SMAD family member 3 | 0.0092118 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.00913761 |
| THRB | thyroid hormone receptor, beta | 0.00895889 |
| RCOR1 | REST corepressor 1 | 0.00892831 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.00886251 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.00875752 |
| KLHL29 | kelch-like family member 29 | 0.00873475 |
| LYST | lysosomal trafficking regulator | 0.00872198 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00867463 |
| EMP1 | epithelial membrane protein 1 | 0.00857388 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.00852183 |
| IL18 | interleukin 18 | 0.00845484 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00844013 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | 0.00842496 |
| NLRC5 | NLR family, CARD domain containing 5 | 0.00840237 |
| DUSP5 | dual specificity phosphatase 5 | 0.00833465 |
| EGFR | epidermal growth factor receptor | 0.00806427 |
| CFAP161 | cilia and flagella associated protein 161 | 0.00794696 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.00793493 |
| LIPH | lipase, member H | 0.00789453 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00783539 |
| PRR5L | proline rich 5 like | 0.0077612 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.00775724 |
| EPHA4 | EPH receptor A4 | 0.00772953 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.00772394 |
| PITRM1 | pitrilysin metallopeptidase 1 | 0.00772376 |
| RASEF | RAS and EF-hand domain containing | 0.00757949 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00750975 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00747666 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00742015 |
| AEBP2 | AE binding protein 2 | 0.00736632 |
| GLRX | glutaredoxin (thioltransferase) | 0.00736391 |
| MSN | moesin | 0.00730393 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.00728897 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.00721189 |
| WLS | wntless Wnt ligand secretion mediator | 0.00717718 |
| EDN1 | endothelin 1 | 0.00708103 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.312645 |
| TMSB10 | thymosin beta 10 | -0.181924 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.179157 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147122 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.138379 |
| RPS6 | ribosomal protein S6 | -0.116485 |
| NPSR1 | neuropeptide S receptor 1 | -0.102545 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0875985 |
| GPHN | gephyrin | -0.0792442 |
| ANXA2 | annexin A2 | -0.0769245 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0764 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0742788 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0730892 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0718955 |
| RPLP1 | ribosomal protein, large, P1 | -0.0702091 |
| EPCAM | epithelial cell adhesion molecule | -0.0654361 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0647974 |
| AHNAK | AHNAK nucleoprotein | -0.0633953 |
| S100A6 | S100 calcium binding protein A6 | -0.0608352 |
| EZR | ezrin | -0.0589082 |
| RPL34 | ribosomal protein L34 | -0.0573712 |
| DSPP | dentin sialophosphoprotein | -0.0571702 |
| RPS19 | ribosomal protein S19 | -0.0558752 |
| RPL12 | ribosomal protein L12 | -0.0548271 |
| CANX | calnexin | -0.054495 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0543548 |
| KIF5B | kinesin family member 5B | -0.0539074 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0525679 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0520189 |
| RPL35A | ribosomal protein L35a | -0.0499831 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0493917 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0475441 |
| GOLGA4 | golgin A4 | -0.0467068 |
| PGK1 | phosphoglycerate kinase 1 | -0.0465083 |
| ZNF292 | zinc finger protein 292 | -0.0460723 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0458849 |
| ENO1 | enolase 1, (alpha) | -0.0457799 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0448092 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0443602 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0440145 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0431494 |
| MED13L | mediator complex subunit 13-like | -0.0431137 |
| RPL23 | ribosomal protein L23 | -0.0417489 |
| KRT8 | keratin 8, type II | -0.0406442 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0402223 |
| ITGA6 | integrin, alpha 6 | -0.0392035 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0391483 |
| KRT18 | keratin 18, type I | -0.0388947 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0380733 |
| RNF43 | ring finger protein 43 | -0.03807 |
| RPLP0 | ribosomal protein, large, P0 | -0.0377252 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0376183 |
| FAM13A | family with sequence similarity 13, member A | -0.0375851 |
| ACTN4 | actinin, alpha 4 | -0.0375165 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0372227 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0369331 |
| PKM | pyruvate kinase, muscle | -0.0366276 |
| ONECUT3 | one cut homeobox 3 | -0.0361412 |
| PIGR | polymeric immunoglobulin receptor | -0.0357998 |
| RPL8 | ribosomal protein L8 | -0.0354431 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.03538 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0350545 |
| RPL36 | ribosomal protein L36 | -0.0347059 |
| RPS21 | ribosomal protein S21 | -0.0345045 |
| FNBP1L | formin binding protein 1-like | -0.0344062 |
| CALR | calreticulin | -0.0341343 |
| RPLP2 | ribosomal protein, large, P2 | -0.0339344 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0338277 |
| LDHA | lactate dehydrogenase A | -0.0332488 |
| MATR3 | matrin 3 | -0.0329892 |
| RPL19 | ribosomal protein L19 | -0.0327522 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0327177 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0326665 |
| TFRC | transferrin receptor | -0.0324321 |
| NCOR1 | nuclear receptor corepressor 1 | -0.032223 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0316929 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0316477 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0316188 |
| RBM25 | RNA binding motif protein 25 | -0.0315009 |
| YBX1 | Y box binding protein 1 | -0.0313538 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0312733 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0310685 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0309493 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0307632 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0307525 |
| RBM39 | RNA binding motif protein 39 | -0.0307273 |
| RPL5 | ribosomal protein L5 | -0.0306732 |
| NFIA | nuclear factor I/A | -0.0302368 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0301786 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0301134 |
| GNAS | GNAS complex locus | -0.030024 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0300207 |
| RPL18 | ribosomal protein L18 | -0.0299974 |
| RPS24 | ribosomal protein S24 | -0.029852 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0298081 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0291251 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0290693 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0289952 |
| RPS8 | ribosomal protein S8 | -0.0289821 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0289478 |
