| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tucidinostat_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | 0.0788592 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0655535 |
| FN1 | fibronectin 1 | 0.0620102 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0567831 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0554855 |
| NRG1 | neuregulin 1 | 0.0498137 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0426284 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0419478 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.037809 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0334938 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0325513 |
| HMGA2 | high mobility group AT-hook 2 | 0.0310059 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0304404 |
| FAM20C | family with sequence similarity 20, member C | 0.0278168 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0253679 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0242084 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0240497 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0233655 |
| INTS6 | integrator complex subunit 6 | 0.0231857 |
| SYT1 | synaptotagmin I | 0.0225227 |
| WLS | wntless Wnt ligand secretion mediator | 0.0221311 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0220389 |
| AUTS2 | autism susceptibility candidate 2 | 0.0212374 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0201205 |
| NEBL | nebulette | 0.0189959 |
| LOXL2 | lysyl oxidase-like 2 | 0.0185786 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0183891 |
| AADAC | arylacetamide deacetylase | 0.0179308 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0178917 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0176059 |
| MEF2A | myocyte enhancer factor 2A | 0.017536 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0175279 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0172223 |
| RHCG | Rh family, C glycoprotein | 0.0172116 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0170747 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0166143 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0164128 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0159415 |
| ATXN1 | ataxin 1 | 0.0154262 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0152436 |
| PLIN2 | perilipin 2 | 0.0151959 |
| MTSS1 | metastasis suppressor 1 | 0.0146403 |
| FBN1 | fibrillin 1 | 0.0144105 |
| SLC44A5 | solute carrier family 44, member 5 | 0.0139427 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0138158 |
| CDK14 | cyclin-dependent kinase 14 | 0.0136143 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0136006 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0135868 |
| GLIS3 | GLIS family zinc finger 3 | 0.0134514 |
| TNS1 | tensin 1 | 0.0132058 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0131391 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0130698 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0130109 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0129722 |
| TGFB1 | transforming growth factor, beta 1 | 0.0127548 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0126019 |
| NAV1 | neuron navigator 1 | 0.0124524 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0123412 |
| HMCN1 | hemicentin 1 | 0.0121437 |
| H1-0 | H1.0 linker histone | 0.0120432 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0120045 |
| ANGPTL4 | angiopoietin-like 4 | 0.0119136 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0118172 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0116656 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0116023 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0114423 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0114321 |
| HDAC4 | histone deacetylase 4 | 0.0113979 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0113335 |
| AVIL | advillin | 0.0113271 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0112891 |
| FAM219A | family with sequence similarity 219, member A | 0.0112851 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0112738 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0112106 |
| MECOM | MDS1 and EVI1 complex locus | 0.0110209 |
| CDH13 | cadherin 13 | 0.0109851 |
| DST | dystonin | 0.0108898 |
| SKIL | SKI-like proto-oncogene | 0.0108875 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0108408 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0107484 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0102636 |
| POU6F2 | POU class 6 homeobox 2 | 0.0102298 |
| PALLD | palladin, cytoskeletal associated protein | 0.0101965 |
| BICC1 | BicC family RNA binding protein 1 | 0.0101239 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0100702 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0100511 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00997529 |
| THRB | thyroid hormone receptor, beta | 0.00987537 |
| CA12 | carbonic anhydrase XII | 0.00985997 |
| SVIL | supervillin | 0.009825 |
| RPL4 | ribosomal protein L4 | 0.00966131 |
| PCNX2 | pecanex 2 | 0.00962914 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00957539 |
| DOCK3 | dedicator of cytokinesis 3 | 0.00947507 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00946611 |
| ZNF804A | zinc finger protein 804A | 0.00942588 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00941133 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00933828 |
| FRMD6 | FERM domain containing 6 | 0.0093293 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.0093105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.182181 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.148969 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148673 |
| TMSB10 | thymosin beta 10 | -0.129915 |
| GOLGA4 | golgin A4 | -0.102979 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0965246 |
| VIM | vimentin | -0.091554 |
| RBM39 | RNA binding motif protein 39 | -0.0866504 |
| USP34 | ubiquitin specific peptidase 34 | -0.0856721 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0840111 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0823166 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0768409 |
| FTL | ferritin, light polypeptide | -0.0753512 |
| PTMA | prothymosin, alpha | -0.0707331 |
| MT2A | metallothionein 2A | -0.0695562 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0669461 |
| PCBP2 | poly(rC) binding protein 2 | -0.0661488 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0582024 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0578487 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0574086 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0554382 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0520004 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0496546 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0494437 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0493542 |
| OGA | O-GlcNAcase | -0.0478919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0465521 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0451639 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0448123 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0424011 |
| OSMR | oncostatin M receptor | -0.0419168 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0418462 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0417944 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0408163 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0406624 |
| CD44 | CD44 molecule (Indian blood group) | -0.040426 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0402283 |
| B2M | beta-2-microglobulin | -0.0394586 |
| SPAG9 | sperm associated antigen 9 | -0.039097 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0387391 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0381104 |
| RPLP1 | ribosomal protein, large, P1 | -0.0380258 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.037957 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0374425 |
| NRP1 | neuropilin 1 | -0.0368662 |
| SMAD3 | SMAD family member 3 | -0.0368087 |
| CANX | calnexin | -0.035793 |
| RPS19 | ribosomal protein S19 | -0.0354097 |
| SBF2 | SET binding factor 2 | -0.0353783 |
| ZNF292 | zinc finger protein 292 | -0.035346 |
| RPS21 | ribosomal protein S21 | -0.0351555 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0351102 |
| PARD3 | par-3 family cell polarity regulator | -0.0348145 |
| COG5 | component of oligomeric golgi complex 5 | -0.0347921 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.034588 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0341937 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336274 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0332847 |
| KIF5B | kinesin family member 5B | -0.0327584 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0327441 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0326424 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0326401 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0319218 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0314331 |
| NF1 | neurofibromin 1 | -0.0313289 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0310747 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0306278 |
| PCNX1 | pecanex 1 | -0.0305975 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0303128 |
| XPO1 | exportin 1 | -0.0301243 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0300505 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0300181 |
| RIOK3 | RIO kinase 3 | -0.0300174 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0298956 |
| GLG1 | golgi glycoprotein 1 | -0.0298585 |
| ATP13A3 | ATPase type 13A3 | -0.0298341 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0297479 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0295461 |
| CLTC | clathrin, heavy chain (Hc) | -0.0294868 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0293954 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0291918 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0290859 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0289228 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0288925 |
| CALR | calreticulin | -0.0288353 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0287874 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0287514 |
| WDR45B | WD repeat domain 45B | -0.0285902 |
| JMJD1C | jumonji domain containing 1C | -0.0285677 |
| WAC | WW domain containing adaptor with coiled-coil | -0.02851 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0284768 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0284681 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.028393 |
| NBAS | neuroblastoma amplified sequence | -0.0283774 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0281767 |
| RBM25 | RNA binding motif protein 25 | -0.0281306 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0280554 |
| TXNRD1 | thioredoxin reductase 1 | -0.0280019 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0279558 |
| RPL35A | ribosomal protein L35a | -0.0279535 |
