| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tucidinostat_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0569925 |
| STC1 | stanniocalcin 1 | 0.0519485 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0370498 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0337548 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0333887 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0328412 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0303171 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0294053 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0291019 |
| ATXN1 | ataxin 1 | 0.0259163 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0254337 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0242746 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0240698 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0238749 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0221897 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0218373 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0218224 |
| WWOX | WW domain containing oxidoreductase | 0.0216116 |
| FLNB | filamin B, beta | 0.0210396 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0208696 |
| NRG1 | neuregulin 1 | 0.0202198 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0200996 |
| NDRG1 | N-myc downstream regulated 1 | 0.02006 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0192653 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0184132 |
| MYO1E | myosin IE | 0.0181931 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0179587 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0178741 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0164367 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0163809 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0159054 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0152517 |
| PDE10A | phosphodiesterase 10A | 0.0147932 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0147539 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0145102 |
| BMP6 | bone morphogenetic protein 6 | 0.0144556 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0141554 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0140281 |
| DST | dystonin | 0.0138265 |
| CMIP | c-Maf inducing protein | 0.0137549 |
| SMYD3 | SET and MYND domain containing 3 | 0.0135372 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0135089 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0134681 |
| ATF6 | activating transcription factor 6 | 0.0129723 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0129073 |
| INTS6 | integrator complex subunit 6 | 0.0127576 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0123911 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0123764 |
| ANGPTL4 | angiopoietin-like 4 | 0.012313 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0122579 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.012135 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0118866 |
| MAP1B | microtubule-associated protein 1B | 0.0117605 |
| EGFR | epidermal growth factor receptor | 0.0114281 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.01127 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0112601 |
| NRXN3 | neurexin 3 | 0.0112284 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.011113 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0109727 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0108956 |
| PRELID2 | PRELI domain containing 2 | 0.0108695 |
| GPHN | gephyrin | 0.0108489 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0106536 |
| LOXL2 | lysyl oxidase-like 2 | 0.0105692 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0104463 |
| MCL1 | myeloid cell leukemia 1 | 0.0103848 |
| GLIS3 | GLIS family zinc finger 3 | 0.0102685 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0100896 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0100506 |
| IER3 | immediate early response 3 | 0.0100304 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.00984417 |
| PRKD1 | protein kinase D1 | 0.00971514 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00970802 |
| MYO10 | myosin X | 0.00968745 |
| TGM2 | transglutaminase 2 | 0.00962489 |
| FMNL2 | formin-like 2 | 0.0095841 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00958087 |
| CYTH1 | cytohesin 1 | 0.00953967 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.00949038 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.00937851 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00927149 |
| PRKCE | protein kinase C, epsilon | 0.00924679 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.00915562 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00905145 |
| MYO1D | myosin ID | 0.0090477 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0090035 |
| NPAS2 | neuronal PAS domain protein 2 | 0.00897149 |
| CD44 | CD44 molecule (Indian blood group) | 0.00893368 |
| SDC4 | syndecan 4 | 0.00892183 |
| NBEAL1 | neurobeachin-like 1 | 0.0089053 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.00887474 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.00877526 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00854313 |
| VCL | vinculin | 0.00852128 |
| PRKCA | protein kinase C, alpha | 0.00847258 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.00840866 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00837903 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00836024 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00835497 |
| NUMB | numb homolog (Drosophila) | 0.00827175 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0970151 |
| TXNRD1 | thioredoxin reductase 1 | -0.0815061 |
| MT2A | metallothionein 2A | -0.0784699 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0682651 |
| FTL | ferritin, light polypeptide | -0.0680293 |
| VIM | vimentin | -0.054904 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0491506 |
| PTMA | prothymosin, alpha | -0.0417556 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0413629 |
| FGB | fibrinogen beta chain | -0.0336849 |
| IGF2 | insulin-like growth factor 2 | -0.0334257 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0331523 |
| RPL23 | ribosomal protein L23 | -0.0318267 |
| GRAMD1B | GRAM domain containing 1B | -0.0314831 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0282043 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0274897 |
| RPL19 | ribosomal protein L19 | -0.0270759 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0269393 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0255343 |
| WDR43 | WD repeat domain 43 | -0.0255046 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0235118 |
| PKM | pyruvate kinase, muscle | -0.0233423 |
| POTEF | POTE ankyrin domain family, member F | -0.0228489 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0227518 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0225252 |
| YBX1 | Y box binding protein 1 | -0.022266 |
| ASPH | aspartate beta-hydroxylase | -0.0222383 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0222378 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0222147 |
| RPS27A | ribosomal protein S27a | -0.0215868 |
| S100A6 | S100 calcium binding protein A6 | -0.0210712 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0208174 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0207307 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0200804 |
| USP3 | ubiquitin specific peptidase 3 | -0.0196727 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.019578 |
| RPLP1 | ribosomal protein, large, P1 | -0.0191062 |
| TPM4 | tropomyosin 4 | -0.0190992 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0187081 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.018588 |
| KIF5B | kinesin family member 5B | -0.0185441 |
| RBM25 | RNA binding motif protein 25 | -0.0177697 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0176846 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.017097 |
| MATR3 | matrin 3 | -0.0167958 |
| PFDN2 | prefoldin subunit 2 | -0.0166947 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0165947 |
| ZNF292 | zinc finger protein 292 | -0.0164868 |
| MYOF | myoferlin | -0.0163596 |
| RBM39 | RNA binding motif protein 39 | -0.0158707 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0157747 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0155871 |
| ECT2 | epithelial cell transforming 2 | -0.0155533 |
| RPS21 | ribosomal protein S21 | -0.0154023 |
| RPL8 | ribosomal protein L8 | -0.0152857 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.015044 |
| RHEB | Ras homolog enriched in brain | -0.0149601 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0149421 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0149194 |
| APP | amyloid beta (A4) precursor protein | -0.0147431 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0146778 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.014647 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0145953 |
| RPS29 | ribosomal protein S29 | -0.0145926 |
| PFN1 | profilin 1 | -0.0145823 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0145361 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0143051 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0143028 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0142303 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0141717 |
| RPL35A | ribosomal protein L35a | -0.0141105 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0139739 |
| SERF2 | small EDRK-rich factor 2 | -0.0138662 |
| ERBIN | erbb2 interacting protein | -0.0138196 |
| RPS12 | ribosomal protein S12 | -0.0137492 |
| ENO1 | enolase 1, (alpha) | -0.0136578 |
| RPS25 | ribosomal protein S25 | -0.0136572 |
| PARD3 | par-3 family cell polarity regulator | -0.013606 |
| ZNF207 | zinc finger protein 207 | -0.0133585 |
| RPS19 | ribosomal protein S19 | -0.0133275 |
| RASAL2 | RAS protein activator like 2 | -0.0132618 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0131819 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0131522 |
| YME1L1 | YME1-like 1 ATPase | -0.0130861 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0130329 |
| CANX | calnexin | -0.0129665 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0129599 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0129365 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0129256 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0128411 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0127952 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0127614 |
| TMEM123 | transmembrane protein 123 | -0.0127262 |
| RPS5 | ribosomal protein S5 | -0.0126978 |
| RPL7 | ribosomal protein L7 | -0.0126843 |
| TMEM87A | transmembrane protein 87A | -0.012649 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0126096 |
| NOP58 | NOP58 ribonucleoprotein | -0.0125999 |
| RPL36 | ribosomal protein L36 | -0.0125867 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.012564 |
