| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tucidinostat_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.121825 |
| KYNU | kynureninase | 0.119357 |
| MYO1E | myosin IE | 0.0873945 |
| EFNA5 | ephrin-A5 | 0.08674 |
| EZR | ezrin | 0.0852883 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0771711 |
| ASPH | aspartate beta-hydroxylase | 0.0660898 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0633668 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0568833 |
| PARD3 | par-3 family cell polarity regulator | 0.0556254 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0529209 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0525788 |
| EXOC4 | exocyst complex component 4 | 0.0506129 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0456414 |
| GRAMD1B | GRAM domain containing 1B | 0.0455117 |
| FRY | furry homolog (Drosophila) | 0.0454955 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0453618 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.044774 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0423662 |
| CMIP | c-Maf inducing protein | 0.0415918 |
| DSPP | dentin sialophosphoprotein | 0.0415241 |
| ITGA6 | integrin, alpha 6 | 0.0414486 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0411648 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.040789 |
| FOXP1 | forkhead box P1 | 0.0401679 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0400265 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0400167 |
| AHNAK | AHNAK nucleoprotein | 0.039989 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.0399145 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0390589 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.038854 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0388254 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0387951 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0385136 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0384281 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0382798 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0382738 |
| RAD51B | RAD51 paralog B | 0.038079 |
| ABLIM1 | actin binding LIM protein 1 | 0.0374874 |
| INTS6 | integrator complex subunit 6 | 0.0374025 |
| MACC1 | metastasis associated in colon cancer 1 | 0.037351 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0373133 |
| MCL1 | myeloid cell leukemia 1 | 0.0366124 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0365407 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0361378 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0355003 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0354442 |
| GOLGB1 | golgin B1 | 0.0350045 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0348592 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0346196 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.034564 |
| SRPK2 | SRSF protein kinase 2 | 0.0342391 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0340402 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0338193 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0334969 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.033056 |
| FAT1 | FAT atypical cadherin 1 | 0.0330229 |
| NABP1 | nucleic acid binding protein 1 | 0.0330109 |
| FOXK1 | forkhead box K1 | 0.0325584 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0325134 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0324608 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0323332 |
| VCL | vinculin | 0.0321766 |
| VMP1 | vacuole membrane protein 1 | 0.0321556 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0317637 |
| N4BP1 | NEDD4 binding protein 1 | 0.0311023 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0308306 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0304629 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0304432 |
| NF1 | neurofibromin 1 | 0.0299732 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0299383 |
| OSMR | oncostatin M receptor | 0.0299011 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0297006 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0296192 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0295968 |
| RNF217 | ring finger protein 217 | 0.0295635 |
| MRPS35 | mitochondrial ribosomal protein S35 | 0.0295629 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0293652 |
| CTBP2 | C-terminal binding protein 2 | 0.0292493 |
| MYOF | myoferlin | 0.0291187 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0290769 |
| MB21D2 | Mab-21 domain containing 2 | 0.0289193 |
| PRSS23 | protease, serine, 23 | 0.0288396 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0288205 |
| VGLL3 | vestigial-like family member 3 | 0.0288202 |
| CDK12 | cyclin-dependent kinase 12 | 0.0285059 |
| BPTF | bromodomain PHD finger transcription factor | 0.0284757 |
| FBXO34 | F-box protein 34 | 0.0283817 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0281135 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0281101 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0280661 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0280392 |
| KIZ | kizuna centrosomal protein | 0.0278514 |
| NBEA | neurobeachin | 0.027817 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0278106 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0276897 |
| SMAD3 | SMAD family member 3 | 0.0276439 |
| SEC24D | SEC24 family member D | 0.0275006 |
| MYO5B | myosin VB | 0.0274915 |
| NBEAL1 | neurobeachin-like 1 | 0.0274441 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.259203 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.16798 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122283 |
| NDRG1 | N-myc downstream regulated 1 | -0.115991 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0990936 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0948518 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0922327 |
| KRT17 | keratin 17, type I | -0.0898672 |
| VIM | vimentin | -0.0876833 |
| RPL35A | ribosomal protein L35a | -0.0749725 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0742597 |
| ACTG1 | actin gamma 1 | -0.0732937 |
| FTL | ferritin, light polypeptide | -0.0731668 |
| RPS6 | ribosomal protein S6 | -0.0716312 |
| LDHA | lactate dehydrogenase A | -0.0656307 |
| TMSB10 | thymosin beta 10 | -0.06338 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0603499 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.059441 |
| RPLP1 | ribosomal protein, large, P1 | -0.0588755 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0572472 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0567395 |
| RPL26 | ribosomal protein L26 | -0.0560345 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0557799 |
| ZNF292 | zinc finger protein 292 | -0.0546457 |
| FAM13A | family with sequence similarity 13, member A | -0.054626 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0544088 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0531941 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0519971 |
| MXD1 | MAX dimerization protein 1 | -0.0517246 |
| LAMC2 | laminin, gamma 2 | -0.050218 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.049862 |
| ADM | adrenomedullin | -0.0489314 |
| RPL37A | ribosomal protein L37a | -0.0485485 |
| FBXO11 | F-box protein 11 | -0.0478668 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0478295 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0477334 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0469554 |
| TXNRD1 | thioredoxin reductase 1 | -0.045432 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0425853 |
| RPS8 | ribosomal protein S8 | -0.0420992 |
| IER3 | immediate early response 3 | -0.0416913 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0415564 |
| JMJD1C | jumonji domain containing 1C | -0.0401141 |
| RACK1 | receptor for activated C kinase 1 | -0.0397555 |
| RPL12 | ribosomal protein L12 | -0.0395647 |
| SFTPA2 | surfactant protein A2 | -0.0394045 |
| MMP1 | matrix metallopeptidase 1 | -0.0389672 |
| RUNX1 | runt-related transcription factor 1 | -0.0388004 |
| GOLGA4 | golgin A4 | -0.0387959 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0385408 |
| CD44 | CD44 molecule (Indian blood group) | -0.038475 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0381942 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0379386 |
| HMGA2 | high mobility group AT-hook 2 | -0.0367383 |
| ATOSA | atos homolog A | -0.0364374 |
| RPL23 | ribosomal protein L23 | -0.0362867 |
| HLA-B | major histocompatibility complex, class I, B | -0.0356942 |
| STC1 | stanniocalcin 1 | -0.0354171 |
| RPS16 | ribosomal protein S16 | -0.0349386 |
| PTMA | prothymosin, alpha | -0.0347195 |
| ABI1 | abl-interactor 1 | -0.0344974 |
| S100A10 | S100 calcium binding protein A10 | -0.0344531 |
| DTNA | dystrobrevin, alpha | -0.0343529 |
| SQSTM1 | sequestosome 1 | -0.0343361 |
| RPS20 | ribosomal protein S20 | -0.0342787 |
| RPS29 | ribosomal protein S29 | -0.0336211 |
| DUSP10 | dual specificity phosphatase 10 | -0.0328216 |
| RPL5 | ribosomal protein L5 | -0.0327603 |
| RPL37 | ribosomal protein L37 | -0.0324886 |
| RIOK3 | RIO kinase 3 | -0.0323533 |
| ABHD17C | abhydrolase domain containing 17C | -0.0318458 |
| RND3 | Rho family GTPase 3 | -0.0317362 |
| RRBP1 | ribosome binding protein 1 | -0.0316251 |
| ANXA1 | annexin A1 | -0.0315324 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0309032 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0308172 |
| MT2A | metallothionein 2A | -0.0306113 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0305584 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0305546 |
| DIAPH2 | diaphanous-related formin 2 | -0.0304075 |
| RTN4 | reticulon 4 | -0.0303497 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0303368 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0303284 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0300941 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0300306 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0298645 |
| RPL28 | ribosomal protein L28 | -0.0297841 |
| RPL8 | ribosomal protein L8 | -0.0297614 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0296212 |
| OGA | O-GlcNAcase | -0.0296051 |
| EMP1 | epithelial membrane protein 1 | -0.0295967 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0295752 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0295523 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0295162 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0291711 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0290209 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0288888 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0287323 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0282005 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0281326 |
