| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0848787 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.081534 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0698621 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0586718 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0513296 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0464962 |
| WWOX | WW domain containing oxidoreductase | 0.0449867 |
| TPM3 | tropomyosin 3 | 0.0442117 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0423348 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0408728 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0393656 |
| VCL | vinculin | 0.0381686 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0366202 |
| POTEF | POTE ankyrin domain family, member F | 0.0315218 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.03035 |
| HDGF | hepatoma-derived growth factor | 0.0299859 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0291746 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0289712 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0288825 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0287611 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0286366 |
| MACROD2 | MACRO domain containing 2 | 0.0285691 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0283608 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0283139 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0278953 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0267856 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0265054 |
| HLA-B | major histocompatibility complex, class I, B | 0.0254954 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0254742 |
| PRELID2 | PRELI domain containing 2 | 0.0252311 |
| HLA-A | major histocompatibility complex, class I, A | 0.0250997 |
| FAM13A | family with sequence similarity 13, member A | 0.0247629 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0247607 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0247301 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0245394 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0244707 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0237236 |
| DTNA | dystrobrevin, alpha | 0.0232719 |
| PDE10A | phosphodiesterase 10A | 0.0229843 |
| VIM | vimentin | 0.0228273 |
| GRAMD1B | GRAM domain containing 1B | 0.0222527 |
| SVIL | supervillin | 0.0219831 |
| PKM | pyruvate kinase, muscle | 0.0219273 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0215075 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0202652 |
| CDCP1 | CUB domain containing protein 1 | 0.0196644 |
| MAGEA4 | melanoma antigen family A4 | 0.0195758 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0195184 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.019218 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0191337 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0190563 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0188628 |
| TRIM9 | tripartite motif containing 9 | 0.0188227 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0187956 |
| SET | SET nuclear proto-oncogene | 0.0185058 |
| CALD1 | caldesmon 1 | 0.0183086 |
| HOMER1 | homer scaffolding protein 1 | 0.0182926 |
| NEBL | nebulette | 0.0180565 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0178255 |
| PNN | pinin, desmosome associated protein | 0.0177666 |
| NRDC | nardilysin convertase | 0.0176943 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0176117 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0175695 |
| SYT1 | synaptotagmin I | 0.0175038 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0174701 |
| SMIM44 | small integral membrane protein 44 | 0.0174685 |
| DSPP | dentin sialophosphoprotein | 0.0174305 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0169891 |
| TPM4 | tropomyosin 4 | 0.0169348 |
| PTMS | parathymosin | 0.0167828 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0167303 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0165848 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0165741 |
| ANXA5 | annexin A5 | 0.0164857 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0161916 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0160549 |
| CCDC88A | coiled-coil domain containing 88A | 0.0159384 |
| PFN1 | profilin 1 | 0.0159072 |
| VMP1 | vacuole membrane protein 1 | 0.0157242 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0157083 |
| TBK1 | TANK-binding kinase 1 | 0.0156838 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0156642 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0156091 |
| FHIT | fragile histidine triad | 0.0155877 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0155526 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0154107 |
| RAI14 | retinoic acid induced 14 | 0.0153695 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0153607 |
| LUZP1 | leucine zipper protein 1 | 0.0152386 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0152174 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0152007 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0151757 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0151319 |
| NUP58 | nucleoporin 58 | 0.0148708 |
| KDM2B | lysine (K)-specific demethylase 2B | 0.0148273 |
| ZNF148 | zinc finger protein 148 | 0.0147925 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0147885 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0145188 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0144628 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0144437 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.134553 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0989098 |
| RAD51B | RAD51 paralog B | -0.0796279 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0732688 |
| NF1 | neurofibromin 1 | -0.0598324 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0580511 |
| USP34 | ubiquitin specific peptidase 34 | -0.055585 |
| ACTG1 | actin gamma 1 | -0.0516546 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0512478 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0511939 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0499341 |
| CAVIN1 | caveolae associated protein 1 | -0.0488725 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0474119 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0457016 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0452148 |
| FBXO11 | F-box protein 11 | -0.0436661 |
| NABP1 | nucleic acid binding protein 1 | -0.0432594 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0421931 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0410965 |
| RPS21 | ribosomal protein S21 | -0.0407763 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0390829 |
| RPS3 | ribosomal protein S3 | -0.0379131 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0372243 |
| RPL12 | ribosomal protein L12 | -0.0370011 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0369309 |
| GPHN | gephyrin | -0.036879 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0360741 |
| RPL23 | ribosomal protein L23 | -0.0359206 |
| PTK2 | protein tyrosine kinase 2 | -0.0357273 |
| RPS8 | ribosomal protein S8 | -0.035446 |
| TMSB10 | thymosin beta 10 | -0.0346508 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0343506 |
| RPLP0 | ribosomal protein, large, P0 | -0.0331935 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0323922 |
| TXNRD1 | thioredoxin reductase 1 | -0.0321297 |
| AHNAK | AHNAK nucleoprotein | -0.0314828 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0312574 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0307914 |
| SRP72 | signal recognition particle 72kDa | -0.0305746 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0302139 |
| RPL37 | ribosomal protein L37 | -0.0299659 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0298353 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0297813 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0295831 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.029548 |
| AEBP2 | AE binding protein 2 | -0.0293588 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.02917 |
| BBX | bobby sox homolog (Drosophila) | -0.0288731 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0288475 |
| LRRC23 | leucine rich repeat containing 23 | -0.028538 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0284189 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.028304 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0280987 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0279977 |
| RPL37A | ribosomal protein L37a | -0.0279403 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0278144 |
| UBC | ubiquitin C | -0.0278138 |
| CLTC | clathrin, heavy chain (Hc) | -0.0276065 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0271674 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0268707 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0268282 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0266851 |
| MCL1 | myeloid cell leukemia 1 | -0.0265491 |
| OGA | O-GlcNAcase | -0.0263861 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0262791 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0262766 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0262648 |
| PCNX1 | pecanex 1 | -0.0260732 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0254895 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0254542 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0250989 |
| RACK1 | receptor for activated C kinase 1 | -0.0250956 |
| TMEM131 | transmembrane protein 131 | -0.0249088 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0247926 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0247732 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0245948 |
| DENND1A | DENN/MADD domain containing 1A | -0.0245188 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0244743 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0243069 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0242572 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0240957 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0240909 |
| RPS29 | ribosomal protein S29 | -0.023678 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0235216 |
| R3HDM2 | R3H domain containing 2 | -0.023407 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.023039 |
| ZNF217 | zinc finger protein 217 | -0.0227308 |
| PKP4 | plakophilin 4 | -0.0227292 |
| RPL6 | ribosomal protein L6 | -0.0226384 |
| RPL26 | ribosomal protein L26 | -0.0221766 |
| RPL13A | ribosomal protein L13a | -0.0221622 |
| CDK13 | cyclin-dependent kinase 13 | -0.0221122 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0219678 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0218559 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0216774 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0214111 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | -0.0213684 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0211921 |
| RPS27 | ribosomal protein S27 | -0.0211246 |
| WDR70 | WD repeat domain 70 | -0.0210955 |
