| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tucidinostat_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.0897715 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.066759 |
| UBC | ubiquitin C | 0.0652405 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.051473 |
| H1-0 | H1.0 linker histone | 0.0464533 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0457243 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0453438 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.045037 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0433798 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0429019 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0424429 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0416706 |
| FLNB | filamin B, beta | 0.0411653 |
| SDC4 | syndecan 4 | 0.0406857 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0386659 |
| RPL4 | ribosomal protein L4 | 0.0371429 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0367312 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0365791 |
| PTMA | prothymosin, alpha | 0.0344829 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0343984 |
| GOLGB1 | golgin B1 | 0.0322352 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0306854 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0298686 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.029803 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0296717 |
| MAP1B | microtubule-associated protein 1B | 0.0295697 |
| RREB1 | ras responsive element binding protein 1 | 0.0292652 |
| RPL35A | ribosomal protein L35a | 0.0291143 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0290115 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0278704 |
| SERINC5 | serine incorporator 5 | 0.0275287 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0273863 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0272349 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0269719 |
| VIM | vimentin | 0.0269085 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0267419 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0265639 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0256394 |
| FNIP1 | folliculin interacting protein 1 | 0.0255337 |
| RTN3 | reticulon 3 | 0.0251792 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0249613 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0243366 |
| RNF213 | ring finger protein 213 | 0.0240602 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0236876 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0234799 |
| MSI2 | musashi RNA-binding protein 2 | 0.0233804 |
| PHF21A | PHD finger protein 21A | 0.023178 |
| VEGFA | vascular endothelial growth factor A | 0.0230491 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0226528 |
| EGR1 | early growth response 1 | 0.0225285 |
| RAD51B | RAD51 paralog B | 0.0223022 |
| HLA-A | major histocompatibility complex, class I, A | 0.0222984 |
| PALLD | palladin, cytoskeletal associated protein | 0.0222442 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0222112 |
| CTBP2 | C-terminal binding protein 2 | 0.0221436 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.022031 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0218329 |
| INTS6 | integrator complex subunit 6 | 0.0216542 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0215011 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0214552 |
| RAI14 | retinoic acid induced 14 | 0.0209665 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0206942 |
| CAVIN1 | caveolae associated protein 1 | 0.0204109 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.019971 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0199592 |
| TUFT1 | tuftelin 1 | 0.0197011 |
| GOLPH3L | golgi phosphoprotein 3-like | 0.0196745 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.019635 |
| TUSC3 | tumor suppressor candidate 3 | 0.0195706 |
| TPM4 | tropomyosin 4 | 0.0191561 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0190513 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0189078 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0188347 |
| RBM47 | RNA binding motif protein 47 | 0.0187597 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0186989 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0186113 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0185024 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0183265 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0182101 |
| RCOR1 | REST corepressor 1 | 0.0179829 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0179785 |
| FBXO11 | F-box protein 11 | 0.0175707 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0171787 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0167903 |
| FAM168A | family with sequence similarity 168, member A | 0.0167624 |
| AHNAK | AHNAK nucleoprotein | 0.0166839 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0163259 |
| AFMID | arylformamidase | 0.0161951 |
| COPA | coatomer protein complex, subunit alpha | 0.0161361 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0160119 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0158722 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0158363 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0158253 |
| RPS29 | ribosomal protein S29 | 0.015769 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0157438 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0157221 |
| UBAP2 | ubiquitin associated protein 2 | 0.0156722 |
| DENND5B | DENN/MADD domain containing 5B | 0.0156058 |
| HDAC9 | histone deacetylase 9 | 0.0155796 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0155145 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.285624 |
| ASPH | aspartate beta-hydroxylase | -0.187471 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.185624 |
| NDRG1 | N-myc downstream regulated 1 | -0.168568 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.154485 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.141348 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.123153 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112615 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0963987 |
| LAMC2 | laminin, gamma 2 | -0.0942163 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0884178 |
| S100A6 | S100 calcium binding protein A6 | -0.0804135 |
| TXNRD1 | thioredoxin reductase 1 | -0.0699348 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0695156 |
| HMGB2 | high mobility group box 2 | -0.0669394 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0638636 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0637319 |
| TMSB10 | thymosin beta 10 | -0.0630478 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.060858 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.060664 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0573231 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0571696 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0566798 |
| HMGA1 | high mobility group AT-hook 1 | -0.0524965 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0522928 |
| LDHA | lactate dehydrogenase A | -0.051561 |
| RPL34 | ribosomal protein L34 | -0.0510163 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0495974 |
| LMO7 | LIM domain 7 | -0.0488905 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.047459 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0473523 |
| TMSB4X | thymosin beta 4, X-linked | -0.0473275 |
| DSG2 | desmoglein 2 | -0.0471514 |
| MT2A | metallothionein 2A | -0.0469914 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0467918 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0458565 |
| RPL32 | ribosomal protein L32 | -0.0458074 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.045296 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0452009 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0451586 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0448866 |
| RPL12 | ribosomal protein L12 | -0.0446132 |
| PAPOLA | poly(A) polymerase alpha | -0.0444635 |
| RPL7 | ribosomal protein L7 | -0.0444393 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0441749 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0435895 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0432478 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0428382 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0425849 |
| RPS3 | ribosomal protein S3 | -0.0423056 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0420139 |
| RPLP0 | ribosomal protein, large, P0 | -0.0418534 |
| CDK17 | cyclin-dependent kinase 17 | -0.0417415 |
| TFG | TRK-fused gene | -0.041497 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0408884 |
| RPLP2 | ribosomal protein, large, P2 | -0.0395518 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0392868 |
| MKI67 | marker of proliferation Ki-67 | -0.0387992 |
| EPCAM | epithelial cell adhesion molecule | -0.0385166 |
| RACK1 | receptor for activated C kinase 1 | -0.0384109 |
| RPS2 | ribosomal protein S2 | -0.0383874 |
| CLINT1 | clathrin interactor 1 | -0.0380466 |
| NCKAP1 | NCK-associated protein 1 | -0.037809 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0377779 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0376631 |
| PGK1 | phosphoglycerate kinase 1 | -0.0376297 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0363951 |
| ARRDC3 | arrestin domain containing 3 | -0.0361092 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0360748 |
| RASA2 | RAS p21 protein activator 2 | -0.0354527 |
| RPS19 | ribosomal protein S19 | -0.034384 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0343201 |
| YBX3 | Y box binding protein 3 | -0.0342591 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0339683 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0337693 |
| GPX4 | glutathione peroxidase 4 | -0.0337492 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0335451 |
| ATP13A3 | ATPase type 13A3 | -0.0332383 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0330545 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0328951 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0328043 |
| NAV2 | neuron navigator 2 | -0.0327512 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0326654 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0321694 |
| NEK7 | NIMA-related kinase 7 | -0.0320058 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0318624 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.031682 |
| RPL11 | ribosomal protein L11 | -0.0316421 |
| ANLN | anillin, actin binding protein | -0.0314147 |
| CCNL1 | cyclin L1 | -0.0311499 |
| S100A10 | S100 calcium binding protein A10 | -0.030919 |
| ADAR | adenosine deaminase, RNA-specific | -0.0309183 |
| CLTC | clathrin, heavy chain (Hc) | -0.0308853 |
| ECT2 | epithelial cell transforming 2 | -0.0303547 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0303489 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0303215 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.030212 |
| OSMR | oncostatin M receptor | -0.0299927 |
| KRT7 | keratin 7, type II | -0.0299202 |
| MYO6 | myosin VI | -0.0296312 |
