| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tucidinostat_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.152271 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.075305 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0613814 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.056841 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0537115 |
| INTS6 | integrator complex subunit 6 | 0.052801 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.049972 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0476288 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.047056 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0443731 |
| LSAMP | limbic system-associated membrane protein | 0.0430753 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0426288 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0409021 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0408383 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0357498 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0350059 |
| PRELID2 | PRELI domain containing 2 | 0.0328796 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0327448 |
| VCL | vinculin | 0.0324967 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0323827 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0309199 |
| SMAD2 | SMAD family member 2 | 0.030893 |
| FMNL2 | formin-like 2 | 0.0303695 |
| AUTS2 | autism susceptibility candidate 2 | 0.0303293 |
| EGR1 | early growth response 1 | 0.0296772 |
| FNDC3A | fibronectin type III domain containing 3A | 0.028359 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0282409 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0275769 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0271607 |
| COL5A2 | collagen, type V, alpha 2 | 0.0264962 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0254827 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.025385 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0251116 |
| DST | dystonin | 0.0249115 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0244332 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0244306 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.024143 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0240682 |
| GRB10 | growth factor receptor-bound protein 10 | 0.02403 |
| NRXN3 | neurexin 3 | 0.0239725 |
| ATXN1 | ataxin 1 | 0.0236931 |
| GPC6 | glypican 6 | 0.0232316 |
| MACROD2 | MACRO domain containing 2 | 0.0229102 |
| BMP6 | bone morphogenetic protein 6 | 0.0229046 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0225683 |
| AEBP2 | AE binding protein 2 | 0.0225266 |
| UNC5D | unc-5 homolog D (C. elegans) | 0.0222139 |
| PCNX2 | pecanex 2 | 0.0214907 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0212317 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0210621 |
| IER3 | immediate early response 3 | 0.0204042 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.019372 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0193219 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.0190104 |
| SVIL | supervillin | 0.0188464 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0187276 |
| GLCCI1 | glucocorticoid induced 1 | 0.0184275 |
| DNER | delta/notch-like EGF repeat containing | 0.018423 |
| HDAC9 | histone deacetylase 9 | 0.0183417 |
| EPHA4 | EPH receptor A4 | 0.0182749 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.018106 |
| CADM2 | cell adhesion molecule 2 | 0.0180922 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0180592 |
| WWOX | WW domain containing oxidoreductase | 0.0177719 |
| SYT1 | synaptotagmin I | 0.0176742 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0176068 |
| SLC38A2 | solute carrier family 38, member 2 | 0.017406 |
| RPL9 | ribosomal protein L9 | 0.0170959 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.017004 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0168541 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0166593 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0164772 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0163433 |
| PRKCA | protein kinase C, alpha | 0.0161489 |
| CNTN1 | contactin 1 | 0.0160584 |
| RAD51B | RAD51 paralog B | 0.0159792 |
| NBEA | neurobeachin | 0.0159736 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0158921 |
| FAM168A | family with sequence similarity 168, member A | 0.0157232 |
| ANGPTL4 | angiopoietin-like 4 | 0.0155353 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0153945 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0152811 |
| POTEF | POTE ankyrin domain family, member F | 0.0151915 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0149598 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0149232 |
| RAB31 | RAB31, member RAS oncogene family | 0.0149145 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0148286 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.014659 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0145997 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0145342 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0144121 |
| CDK14 | cyclin-dependent kinase 14 | 0.0144059 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0143125 |
| CUX1 | cut-like homeobox 1 | 0.014195 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0141889 |
| MYO1E | myosin IE | 0.0141697 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0140691 |
| FRMD5 | FERM domain containing 5 | 0.0140511 |
| MCL1 | myeloid cell leukemia 1 | 0.0138096 |
| OXSR1 | oxidative stress responsive 1 | 0.0138049 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.235253 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.159364 |
| EFNA5 | ephrin-A5 | -0.156848 |
| TXNRD1 | thioredoxin reductase 1 | -0.144781 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.139231 |
| ASPH | aspartate beta-hydroxylase | -0.138605 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.124609 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.124578 |
| FN1 | fibronectin 1 | -0.117819 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116273 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.102657 |
| CANX | calnexin | -0.0906655 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0730851 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0722636 |
| PTMA | prothymosin, alpha | -0.0708685 |
| PGK1 | phosphoglycerate kinase 1 | -0.0674429 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0666866 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0627781 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0610791 |
| GRAMD1B | GRAM domain containing 1B | -0.0584079 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.055473 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0535938 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0523406 |
| RTN4 | reticulon 4 | -0.0514329 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0504603 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.05031 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0492058 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0487391 |
| GOLGA4 | golgin A4 | -0.0458607 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.045255 |
| OGA | O-GlcNAcase | -0.0444163 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0444145 |
| NEK7 | NIMA-related kinase 7 | -0.0436946 |
| TNPO1 | transportin 1 | -0.0429937 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0424991 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0415896 |
| FTL | ferritin, light polypeptide | -0.0412591 |
| MATR3 | matrin 3 | -0.0411931 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0410369 |
| MFF | mitochondrial fission factor | -0.0407062 |
| SMYD3 | SET and MYND domain containing 3 | -0.0406158 |
| SPAG9 | sperm associated antigen 9 | -0.0404629 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0397426 |
| RBM39 | RNA binding motif protein 39 | -0.0391971 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0384013 |
| RPL12 | ribosomal protein L12 | -0.0380879 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0379109 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0379001 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0378886 |
| MYOF | myoferlin | -0.0377925 |
| VIM | vimentin | -0.0372074 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0363351 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0360124 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0358225 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0354005 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.03501 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0347101 |
| LDHA | lactate dehydrogenase A | -0.0344456 |
| CTSL | cathepsin L | -0.0338923 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0338246 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0335448 |
| PYGL | phosphorylase, glycogen, liver | -0.0333686 |
| TPR | translocated promoter region, nuclear basket protein | -0.0333441 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0332436 |
| ANXA1 | annexin A1 | -0.0332271 |
| RPS2 | ribosomal protein S2 | -0.0329725 |
| PTGR1 | prostaglandin reductase 1 | -0.0328181 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0326141 |
| MT2A | metallothionein 2A | -0.0320519 |
| CTSC | cathepsin C | -0.0318162 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0316918 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0314306 |
| SRGN | serglycin | -0.0313105 |
| TMSB10 | thymosin beta 10 | -0.0312918 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0309999 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0308331 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0307765 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0306907 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0306877 |
| CENPF | centromere protein F, 350/400kDa | -0.0302094 |
| CEP350 | centrosomal protein 350kDa | -0.0300701 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0300698 |
| B2M | beta-2-microglobulin | -0.0299237 |
| S100A6 | S100 calcium binding protein A6 | -0.0299132 |
| MKI67 | marker of proliferation Ki-67 | -0.0297429 |
| RPS6 | ribosomal protein S6 | -0.0296347 |
| RAB10 | RAB10, member RAS oncogene family | -0.0295374 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0293931 |
| RGS2 | regulator of G-protein signaling 2 | -0.0293672 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0289473 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0289238 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0285316 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0284973 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0283275 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0282659 |
| NCOR1 | nuclear receptor corepressor 1 | -0.028239 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0280862 |
| HDLBP | high density lipoprotein binding protein | -0.02789 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0278667 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0277497 |
