| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | 0.142353 |
| IGF2 | insulin-like growth factor 2 | 0.125705 |
| DSCAM | Down syndrome cell adhesion molecule | 0.123618 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.122107 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.112272 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0896923 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0858383 |
| GOLGB1 | golgin B1 | 0.0830036 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0773443 |
| DSPP | dentin sialophosphoprotein | 0.0761661 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0701502 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0692364 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0684159 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0649597 |
| FNIP1 | folliculin interacting protein 1 | 0.0644343 |
| RTN4 | reticulon 4 | 0.0643232 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0638536 |
| ZNF638 | zinc finger protein 638 | 0.0636552 |
| SQSTM1 | sequestosome 1 | 0.0626964 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0601936 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0593714 |
| TENM3 | teneurin transmembrane protein 3 | 0.0567729 |
| ERBIN | erbb2 interacting protein | 0.0554292 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0548516 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0546958 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0546851 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0517539 |
| RAB10 | RAB10, member RAS oncogene family | 0.0494093 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0493819 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0486274 |
| INTS6 | integrator complex subunit 6 | 0.0485141 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0484085 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0477686 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0476294 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0474241 |
| LAMA4 | laminin, alpha 4 | 0.0473652 |
| ANXA2 | annexin A2 | 0.0471332 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0462606 |
| CUL4A | cullin 4A | 0.0461515 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0461494 |
| CANX | calnexin | 0.0453443 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.044208 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0440189 |
| HMGA2 | high mobility group AT-hook 2 | 0.0435999 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0433613 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0432347 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0431422 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0429938 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0426488 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0422321 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0407916 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0407696 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0405785 |
| HMGA1 | high mobility group AT-hook 1 | 0.0402958 |
| ATXN7 | ataxin 7 | 0.040237 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0399765 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0393909 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0382143 |
| CTBP2 | C-terminal binding protein 2 | 0.0381909 |
| LMO7 | LIM domain 7 | 0.0379225 |
| SMAD3 | SMAD family member 3 | 0.0378198 |
| PRELID2 | PRELI domain containing 2 | 0.0375832 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0371866 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0365773 |
| MYO1E | myosin IE | 0.0362574 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0360217 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.034848 |
| STC1 | stanniocalcin 1 | 0.0346262 |
| H3-3B | H3.3 histone B | 0.0345679 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0345231 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0345046 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0341194 |
| APP | amyloid beta (A4) precursor protein | 0.0339291 |
| CERS6 | ceramide synthase 6 | 0.0338524 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0338243 |
| MED13 | mediator complex subunit 13 | 0.0336828 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0336412 |
| SYT1 | synaptotagmin I | 0.0332016 |
| HDAC8 | histone deacetylase 8 | 0.0329839 |
| LSAMP | limbic system-associated membrane protein | 0.0329663 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0329095 |
| TXNIP | thioredoxin interacting protein | 0.0325957 |
| ADIPOR2 | adiponectin receptor 2 | 0.0325417 |
| DST | dystonin | 0.0320879 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0320125 |
| GLG1 | golgi glycoprotein 1 | 0.0318748 |
| DENND5B | DENN/MADD domain containing 5B | 0.0314122 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0305583 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0302817 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0300945 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0300523 |
| TXNRD1 | thioredoxin reductase 1 | 0.0296806 |
| BBX | bobby sox homolog (Drosophila) | 0.0296408 |
| PCNX4 | pecanex 4 | 0.0294036 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.029273 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0286491 |
| EGFR | epidermal growth factor receptor | 0.0279768 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0279647 |
| CUX1 | cut-like homeobox 1 | 0.0276775 |
| PGK1 | phosphoglycerate kinase 1 | 0.0272888 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.291398 |
| EFNA5 | ephrin-A5 | -0.220681 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.150027 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.148618 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.118118 |
| GPC6 | glypican 6 | -0.113307 |
| RPS6 | ribosomal protein S6 | -0.105097 |
| ASPH | aspartate beta-hydroxylase | -0.103055 |
| TMSB10 | thymosin beta 10 | -0.100373 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0969912 |
| VCL | vinculin | -0.0956953 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0860285 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0803229 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0725696 |
| SMYD3 | SET and MYND domain containing 3 | -0.0718411 |
| COL5A2 | collagen, type V, alpha 2 | -0.0712431 |
| RORA | RAR-related orphan receptor A | -0.0695544 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0685152 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0681885 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0667384 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0661043 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0650776 |
| MT2A | metallothionein 2A | -0.0632232 |
| NHSL1 | NHS-like 1 | -0.0619591 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0613762 |
| OGA | O-GlcNAcase | -0.0608216 |
| PTMA | prothymosin, alpha | -0.0600015 |
| SETD5 | SET domain containing 5 | -0.0579762 |
| FAM13A | family with sequence similarity 13, member A | -0.0558175 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0555688 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0535608 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0521922 |
| CDH13 | cadherin 13 | -0.0521658 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0520284 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0511115 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0504904 |
| RAD51B | RAD51 paralog B | -0.0495445 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0476965 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0463912 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.045967 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0459195 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0451504 |
| DTNA | dystrobrevin, alpha | -0.0446775 |
| FN1 | fibronectin 1 | -0.0443446 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0442486 |
| RPL23 | ribosomal protein L23 | -0.0441397 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0440691 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0426105 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.040604 |
| PKM | pyruvate kinase, muscle | -0.0401869 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0391752 |
| VIM | vimentin | -0.038582 |
| STAG2 | stromal antigen 2 | -0.0375119 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0367121 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0365776 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0360742 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0356561 |
| USP15 | ubiquitin specific peptidase 15 | -0.0351211 |
| RPS8 | ribosomal protein S8 | -0.0344692 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0339492 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.033731 |
| ACTG1 | actin gamma 1 | -0.0325096 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0323149 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0311489 |
| RPS23 | ribosomal protein S23 | -0.0281466 |
| MYOF | myoferlin | -0.0281174 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.027729 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0268898 |
| TOP1 | topoisomerase (DNA) I | -0.0266431 |
| ZNF292 | zinc finger protein 292 | -0.0262105 |
| RPLP2 | ribosomal protein, large, P2 | -0.0259136 |
| GOLGA4 | golgin A4 | -0.0254983 |
| COG5 | component of oligomeric golgi complex 5 | -0.025387 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0249944 |
| RPS13 | ribosomal protein S13 | -0.0241588 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0235293 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0233184 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0233006 |
| RPS27A | ribosomal protein S27a | -0.0231289 |
| RPL26 | ribosomal protein L26 | -0.0230019 |
| BPTF | bromodomain PHD finger transcription factor | -0.0229588 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.022653 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0221636 |
| RPL35A | ribosomal protein L35a | -0.0220874 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.021882 |
| RPS3 | ribosomal protein S3 | -0.0215553 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0208555 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0205443 |
| RPL11 | ribosomal protein L11 | -0.0198771 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0197521 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0195409 |
| DENND1A | DENN/MADD domain containing 1A | -0.0194028 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0191503 |
| RPS12 | ribosomal protein S12 | -0.018752 |
| RPL36 | ribosomal protein L36 | -0.0186454 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0172136 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0168859 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0157675 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0155544 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.015474 |
