| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.116675 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0778769 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0569533 |
| JMJD1C | jumonji domain containing 1C | 0.052785 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0521348 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0506945 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0501303 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0464477 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0453468 |
| METAP2 | methionyl aminopeptidase 2 | 0.0429505 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0387815 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0377102 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0368739 |
| PLPP1 | phospholipid phosphatase 1 | 0.0368526 |
| TSC22D2 | TSC22 domain family, member 2 | 0.036291 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0357395 |
| NRG1 | neuregulin 1 | 0.0353175 |
| ITGAV | integrin, alpha V | 0.035049 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0343532 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0333412 |
| RBM25 | RNA binding motif protein 25 | 0.0330015 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0329915 |
| FAM171B | family with sequence similarity 171, member B | 0.0322753 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0319533 |
| ENAH | enabled homolog (Drosophila) | 0.0313999 |
| MEF2C | myocyte enhancer factor 2C | 0.0312536 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0300912 |
| NFIB | nuclear factor I/B | 0.0295973 |
| PCBP2 | poly(rC) binding protein 2 | 0.0292129 |
| RNF13 | ring finger protein 13 | 0.0285183 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.028414 |
| MEF2A | myocyte enhancer factor 2A | 0.0280237 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0277983 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0276226 |
| GOLGA4 | golgin A4 | 0.0271854 |
| FIGN | fidgetin | 0.0271508 |
| MEMO1 | mediator of cell motility 1 | 0.0270422 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0269307 |
| ZNF608 | zinc finger protein 608 | 0.0265083 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0261366 |
| FRMD5 | FERM domain containing 5 | 0.0260856 |
| CCNL1 | cyclin L1 | 0.0259752 |
| CDC14A | cell division cycle 14A | 0.025397 |
| USP34 | ubiquitin specific peptidase 34 | 0.0250948 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0249435 |
| RIGI | RNA sensor RIG-I | 0.024761 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0247184 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0245858 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0245355 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0245228 |
| CCNYL1 | cyclin Y-like 1 | 0.0242099 |
| SRPK2 | SRSF protein kinase 2 | 0.023933 |
| MATR3 | matrin 3 | 0.023655 |
| ETNK1 | ethanolamine kinase 1 | 0.0235762 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0232487 |
| TMEM135 | transmembrane protein 135 | 0.0232011 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0231497 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0231069 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.023053 |
| WDR43 | WD repeat domain 43 | 0.0230351 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0224572 |
| TMEM64 | transmembrane protein 64 | 0.0224355 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0224083 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0224021 |
| SLC25A2 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 | 0.0223279 |
| TOX | thymocyte selection-associated high mobility group box | 0.0223025 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0222016 |
| SALL4 | spalt-like transcription factor 4 | 0.0221776 |
| SFSWAP | splicing factor, suppressor of white-apricot family | 0.0221226 |
| TPM1 | tropomyosin 1 (alpha) | 0.0220813 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0209368 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0208015 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0207557 |
| TOP1 | topoisomerase (DNA) I | 0.0205655 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0205505 |
| FANCL | Fanconi anemia, complementation group L | 0.0203202 |
| SATB2 | SATB homeobox 2 | 0.0201876 |
| CPA6 | carboxypeptidase A6 | 0.0200682 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.019982 |
| SHROOM3 | shroom family member 3 | 0.0198903 |
| SLMAP | sarcolemma associated protein | 0.0197913 |
| OPHN1 | oligophrenin 1 | 0.0197262 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0196093 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.019498 |
| NFIA | nuclear factor I/A | 0.0194639 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0191494 |
| HEATR5A | HEAT repeat containing 5A | 0.0191128 |
| UBN2 | ubinuclein 2 | 0.01908 |
| FOXO1 | forkhead box O1 | 0.0188337 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0188054 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0187983 |
| CDV3 | CDV3 homolog (mouse) | 0.0187931 |
| CD2AP | CD2-associated protein | 0.0186855 |
| TFG | TRK-fused gene | 0.0186027 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 | 0.0185866 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0185743 |
| FYCO1 | FYVE and coiled-coil domain containing 1 | 0.0185313 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0185231 |
| APMAP | adipocyte plasma membrane associated protein | 0.0184496 |
| BNC2 | basonuclin 2 | 0.0182586 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.167734 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.151315 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.13201 |
| GPC3 | glypican 3 | -0.127412 |
| COL11A1 | collagen, type XI, alpha 1 | -0.116004 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11045 |
| RPS16 | ribosomal protein S16 | -0.0872813 |
| PTMA | prothymosin, alpha | -0.0760471 |
| RPS6 | ribosomal protein S6 | -0.0748096 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0733994 |
| COL3A1 | collagen, type III, alpha 1 | -0.0725772 |
| PGK1 | phosphoglycerate kinase 1 | -0.0719425 |
| RPL23 | ribosomal protein L23 | -0.0666277 |
| TMSB10 | thymosin beta 10 | -0.0665808 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0665231 |
| CALR | calreticulin | -0.0632055 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0610619 |
| ACTG1 | actin gamma 1 | -0.0608698 |
| RPLP1 | ribosomal protein, large, P1 | -0.0597732 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.059209 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0569111 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0564223 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0562413 |
| SMYD3 | SET and MYND domain containing 3 | -0.0562195 |
| PHIP | pleckstrin homology domain interacting protein | -0.0548871 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0539898 |
| RPLP0 | ribosomal protein, large, P0 | -0.0536186 |
| DST | dystonin | -0.0528136 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0526733 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0506306 |
| COL1A2 | collagen, type I, alpha 2 | -0.0499905 |
| PEG10 | paternally expressed 10 | -0.0498677 |
| RPS8 | ribosomal protein S8 | -0.0495487 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0470337 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.046652 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0462279 |
| GNAS | GNAS complex locus | -0.0461837 |
| RPS12 | ribosomal protein S12 | -0.0459931 |
| RPS13 | ribosomal protein S13 | -0.0458393 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0443846 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0439283 |
| SNX6 | sorting nexin 6 | -0.0432285 |
| YBX1 | Y box binding protein 1 | -0.0430341 |
| MAP4 | microtubule-associated protein 4 | -0.0423822 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0419406 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0416167 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0409113 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0405974 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0403652 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0403063 |
| RACK1 | receptor for activated C kinase 1 | -0.0399842 |
| LDHA | lactate dehydrogenase A | -0.0399469 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0398721 |
| RPL34 | ribosomal protein L34 | -0.0395812 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0394049 |
| CEP350 | centrosomal protein 350kDa | -0.0393672 |
| RPL5 | ribosomal protein L5 | -0.039349 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0390779 |
| DMD | dystrophin | -0.0382642 |
| RAI1 | retinoic acid induced 1 | -0.038022 |
| ENO1 | enolase 1, (alpha) | -0.0378821 |
| RPL35A | ribosomal protein L35a | -0.0375749 |
| NTM | neurotrimin | -0.0375708 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0369889 |
| TFRC | transferrin receptor | -0.0365589 |
| SSR1 | signal sequence receptor, alpha | -0.0360899 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0359691 |
| RPL7 | ribosomal protein L7 | -0.0357534 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0350977 |
| TPR | translocated promoter region, nuclear basket protein | -0.0349068 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0349031 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0341866 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | -0.0337183 |
| PARD3 | par-3 family cell polarity regulator | -0.0336758 |
| RPL36A | ribosomal protein L36a | -0.0336653 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0336578 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0334834 |
| RPS2 | ribosomal protein S2 | -0.0328312 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0327231 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0326864 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0324995 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0323509 |
| LYST | lysosomal trafficking regulator | -0.0322951 |
| RPL26 | ribosomal protein L26 | -0.0321052 |
| PTK2 | protein tyrosine kinase 2 | -0.032055 |
| HMGB2 | high mobility group box 2 | -0.0320168 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0319453 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0317409 |
| FST | follistatin | -0.0316908 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0315316 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0314129 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | -0.0309866 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0307614 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0306941 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0305219 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0305041 |
| ZNF609 | zinc finger protein 609 | -0.0304693 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0302406 |
| RPS21 | ribosomal protein S21 | -0.030163 |
| TRIM2 | tripartite motif containing 2 | -0.0301145 |
